Search Results - "Bates, Steven E."

DNA Advanced Glycation End Products (DNA-AGEs) Are Elevated in Urine and Tissue in an Animal Model of Type 2 Diabetes by Jaramillo, Richard, Shuck, Sarah C, Chan, Yin S, Liu, Xueli, Bates, Steven E, Lim, Punnajit P, Tamae, Daniel, Lacoste, Sandrine, O’Connor, Timothy R, Termini, John

“…More precise identification and treatment monitoring of prediabetic/diabetic individuals will require additional biomarkers to complement existing diagnostic…”
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Mutation Analysis in Cultured Cells of Transgenic Rodents by Besaratinia, Ahmad, Zheng, Albert, Bates, Steven E, Tommasi, Stella

“…To comply with guiding principles for the ethical use of animals for experimental research, the field of mutation research has witnessed a shift of interest…”
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Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C by Besaratinia, Ahmad, Kim, Sang-in, Bates, Steven E, Pfeifer, Gerd P

“…An increasingly popular theory ascribes UVA (>320-400 nm) carcinogenicity to the ability of this wavelength to trigger intracellular photosensitization…”
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DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells by Luo, Li Z, Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L, Park, Sang-Won, Bates, Steven E, Zeng, Xianmin, Iverson, Linda E, O'Connor, Timothy R

“…The potential for human disease treatment using human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells (iPSCs), also…”
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Nucleotide Excision Repair Eliminates Unique DNA-Protein Cross-links from Mammalian Cells by Baker, David J., Wuenschell, Gerald, Xia, Liqun, Termini, John, Bates, Steven E., Riggs, Arthur D., O’Connor, Timothy R.

“…DNA-protein cross-links (DPCs) present a formidable obstacle to cellular processes because they are “superbulky” compared with the majority of chemical…”
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Gamma irradiation does not induce detectable changes in DNA methylation directly following exposure of human cells by Lahtz, Christoph, Bates, Steven E, Jiang, Yong, Li, Arthur X, Wu, Xiwei, Hahn, Maria A, Pfeifer, Gerd P

“…Environmental chemicals and radiation have often been implicated in producing alterations of the epigenome thus potentially contributing to cancer and other…”
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Spontaneous and photosensitization-induced mutations in primary mouse cells transitioning through senescence and immortalization by Caliri, Andrew W., Tommasi, Stella, Bates, Steven E., Besaratinia, Ahmad

“…To investigate the role of oxidative stress–induced DNA damage and mutagenesis in cellular senescence and immortalization, here we profiled spontaneous and…”
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Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization by Tommasi, Stella, Zheng, Albert, Weninger, Annette, Bates, Steven E., Li, Xuejun Arthur, Wu, Xiwei, Hollstein, Monica, Besaratinia, Ahmad

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Correction: DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells by Luo, Li Z., Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L., Park, Sang-Won, Bates, Steven E., Zeng, Xianmin, Iverson, Linda E., O'Connor, Timothy R.

“…The author's affiliation is 2 Department of Stem Cell Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United…”
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Limited mutagenicity of electronic cigarettes in mouse or human cells in vitro by Tommasi, Stella, Bates, Steven E., Behar, Rachel Z., Talbot, Prue, Besaratinia, Ahmad

“…•E-cig are increasingly popular among adult chronic smokers and adolescent never smokers.•The carcinogenic potential of e-cig use in humans is unknown.•E-cig…”
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UVB irradiation does not directly induce detectable changes of DNA methylation in human keratinocytes [version 1; peer review: 2 approved] by Lahtz, Christoph, Kim, Sang-In, Bates, Steven E, Li, Arthur X, Wu, Xiwei, Pfeifer, Gerd P

“…Unprotected exposure to UVB radiation from the sun and the resulting DNA damage are thought to be responsible for physiological changes in the skin and for a…”
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Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization by Tommasi, Stella, Zheng, Albert, Weninger, Annette, Bates, Steven E, Li, Xuejun Arthur, Wu, Xiwei, Hollstein, Monica, Besaratinia, Ahmad

“…Progression to malignancy requires that cells overcome senescence and switch to an immortal phenotype. Thus, exploring the genetic and epigenetic changes that…”
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Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts by Nay, Stephanie L., Lee, Dong-Hyun, Bates, Steven E., O’Connor, Timothy R.

“…► Alkbh2 and Alkbh3 are Fe(II)/α-ketoglutarate-dependent dioxygenases both protect primary MEFs from cytotoxic alkylation damage. ► Only Alkbh2 protects…”
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Human 3-Methyladenine-DNA Glycosylase: Effect of Sequence Context on Excision, Association with PCNA, and Stimulation by AP Endonuclease by Xia, Liqun, Zheng, Li, Lee, Hyun-Wook, Bates, Steven E., Federico, Laura, Shen, Binghui, O'Connor, Timothy R.

“…Human 3-methyladenine-DNA glycosylase (MPG protein) is involved in the base excision repair (BER) pathway responsible mainly for the repair of small DNA base…”
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Classical cytogenetics: karyotyping techniques by Bates, Steven E

“…Classical cytogenetics by karyotyping has been utilized in clinical research laboratories for more than 50 years and remains the key method used in the stem…”
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Similar Mutagenicity of Photoactivated Porphyrins and Ultraviolet A Radiation in Mouse Embryonic Fibroblasts:  Involvement of Oxidative DNA Lesions in Mutagenesis by Besaratinia, Ahmad, Bates, Steven E, Synold, Timothy W, Pfeifer, Gerd P

“…Ultraviolet A (UVA) radiation is implicated in the etiology of human skin cancer. However, the underlying mechanism of carcinogenicity for UVA is not fully…”
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Mutational signature of the proximate bladder carcinogen N-hydroxy-4-acetylaminobiphenyl: Inconsistency with the p53 mutational spectrum in bladder cancer by BESARATINIA, Ahmad, BATES, Steven E, PFEIFER, Gerd P

“…We studied the mutagenicity of the proximate bladder carcinogen, N-hydroxy-4-acetylaminobiphenyl (N-OH-AABP) in embryonic fibroblasts of the Big Blue mouse…”
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Repair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts by Bates, Steven E., Zhou, Ning Ye, Federico, Laura E., Xia, Liqun, O'Connor, Timothy R.

“…The progression of a normal cell to senescence in vivo and in vitro is accompanied by a reduction in the length of the telomeres, the chromosome capping…”
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Efficient Repair of Cyclobutane Pyrimidine Dimers at Mutational Hot Spots is Restored in Complemented Xeroderma Pigmentosum Group C and Trichothiodystrophy/Xeroderma Pigmentosum Group D Cells by Zhou, Ning Ye, Bates, Steven E, Bouziane, Mohammed, Stary, Anne, Sarasin, Alain, O'Connor, Timothy R

“…Xeroderma pigmentosum (XP) and trichothiodystrophy (TTD) are rare heritable diseases. Patients suffering from XP and 50% of TTD afflicted individuals are…”
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Correction: DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells by Luo, Li Z., Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L., Park, Sang-Won, Bates, Steven E., Zeng, Xianmin, Iverson, Linda E., O'Connor, Timothy R.

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