Search Results - "Bates, G P"

Fluid losses and hydration status of industrial workers under thermal stress working extended shifts by Brake, D J, Bates, G P

“…Aims: To assess whether workers under significant thermal stress necessarily dehydrated during their exposure and whether “involuntary dehydration” was…”
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Formation of Polyglutamine Inclusions in Non-CNS Tissue by Sathasivam, Kirupa, Hobbs, Carl, Turmaine, Mark, Mangiarini, Laura, Mahal, Amarbirpal, Bertaux, Fabien, Wanker, Erich E., Doherty, Pat, Davies, Stephen W., Bates, Gillian P.

“…Huntington's disease (HD) is one of a class of inherited progressive neurodegenerative disorders that are caused by a CAG/polyglutamine repeat expansion. We…”
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Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain by DiFiglia, Marian, Sapp, Ellen, Chase, Kathryn O., Davies, Stephen W., Bates, Gillian P., Vonsattel, J. P., Aronin, Neil

“…The cause of neurodegeneration in Huntington's disease (HD) is unknown. Patients with HD have an expanded NH$_2$-terminal polyglutamine region in huntingtin…”
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Impaired Glutamate Uptake in the R6 Huntington's Disease Transgenic Mice by Liévens, J.-C., Woodman, B., Mahal, A., Spasic-Boscovic, O., Samuel, D., Kerkerian-Le Goff, L., Bates, G.P.

“…Huntington's disease (HD) is a late-onset neurodegenerative disease for which the mutation is CAG/polyglutamine repeat expansion. The R6 mouse lines expressing…”
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A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis by Hoff, William van't, Bates, Gillian P, Antignac, Corinne, Jean, Geneviève, Forestier, Lionel, Gribouval, Olivier, Whitmore, Scott A, Town, Margaret, Broyer, Michel, Cherqui, Stèphanie, Attard, Marlene, Callen, David F

“…Nephropathic cystinosis, an autosomal recessive disorder resulting from defective lysosomal transport of cystine, is the most common inherited cause of renal…”
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Inclusion formation in Huntington's disease R6/2 mouse muscle cultures by Orth, M., Cooper, J. M., Bates, G. P., Schapira, A. H. V.

“…Huntington's disease (HD) is an autosomal dominant disorder caused by an expansion in the number of glutamine repeats in the N‐terminal region of the…”
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Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation by Mangiarini, Laura, Sathasivam, Kirupa, Mahal, Amarbirpal, Mott, Richard, Seller, Mary, Bates, Gillian P

“…Six inherited neurodegenerative diseases are caused by a CAG/polyglutamine expansion, including spinal and bulbar muscular atrophy (SBMA), Huntington's disease…”
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Ultrastructural Localization and Progressive Formation of Neuropil Aggregates in Huntington's Disease Transgenic Mice by Li, He, Li, Shi-Hua, Cheng, Anna L., Mangiarini, Laura, Bates, Gillian P., Li, Xiao-Jiang

“…How aggregates of polyglutamine proteins are involved in the neurological symptoms of glutamine repeat diseases is unknown. We show that huntingtin aggregates…”
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Sequence Comparison of Human and Yeast Telomeres Identifies Structurally Distinct Subtelomeric Domains by Flint, J., Bates, G. P., Clark, K., Dorman, A., Willingham, D., Roe, B. A., Micklem, G., Higgs, D. R., Louis, E. J.

“…We have sequenced and compared DNA from the ends of three human chromosomes: 4p, 16p and 22q. In all cases the pro-terminal regions are subdivided by…”
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Heat exhaustion in a deep underground metalliferous mine by Donoghue, A Michael, Sinclair, Murray J, Bates, Graham P

“…OBJECTIVES To examine the incidence, clinical state, personal risk factors, haematology, and biochemistry of heat exhaustion occurring at a deep underground…”
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Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions? by Davies, Stephen W, Beardsall, Kathryn, Turmaine, Mark, DiFiglia, Marian, Aronin, Neil, Bates, Gillian P

“…Neuronal intranuclear inclusions have been found in the brain of a transgenic mouse model of Huntington's disease and in necropsy brain tissue of patients with…”
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Inter- and intra-specific variation within the genus Psoroptes (Acari: Psoroptidae) by Bates, P.G.

“…In this paper the taxonomy and relative importance of various species within the genus Psoroptes are reviewed with respect to inter- and intra-specific…”
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Fatigue in industrial workers under thermal stress on extended shift lengths by Brake, D. J., Bates, G. P.

“…A field investigation to examine the fatigue levels in industrial workers working extended (10, 12 and 12.5 h) shifts under significant levels of thermal…”
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Amyloid-like inclusions in Huntington’s disease by McGowan, D.P., van Roon-Mom, W., Holloway, H., Bates, G.P., Mangiarini, L., Cooper, G.J.S., Faull, R.L.M., Snell, R.G.

“…Huntington’s disease is a progressive, autosomal dominantly inherited, neurodegenerative disease that is characterized by involuntary movements (chorea),…”
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Transgenic Models of Huntington's Disease by Bates, Gillian P., Mangiarini, Laura, Mahal, Amarbirpal, Davies, Stephen W.

“…CAG/polyglutamine expansion has been shown to form the molecular basis of an increasing number of inherited neurodegenerative diseases. The mutation is likely…”
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Brain Neurotransmitter Deficits in Mice Transgenic for the Huntington’s Disease Mutation by Reynolds, Gavin P., Dalton, Caroline F., Tillery, Claire L., Mangiarini, Laura, Davies, Stephen W., Bates, Gillian P.

“…: Huntington’s disease (HD) is associated with an expansion in the CAG repeat sequence of a gene on chromosome 4, resulting in a neurodegenerative process…”
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The risk of heat exhaustion at a deep underground metalliferous mine in relation to body-mass index and predicted VO2max by DONOGHUE, A. M, BATES, G. P

“…The risk of heat exhaustion at a deep underground metalliferous mine was assessed in relation to the body-mass index (BMI) and predicted maximal oxygen uptake…”
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The Risk of Heat Exhaustion at a Deep Underground Metalliferous Mine in Relation to Surface Temperatures by Donoghue, A. M., Bates, G. P.

“…The risk of heat exhaustion at a deep underground metalliferous mine was assessed in relation to thermal conditions prevailing on the surface. For each day of…”
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Suberoylanilide Hydroxamic Acid, a Histone Deacetylase Inhibitor, Ameliorates Motor Deficits in a Mouse Model of Huntington's Disease by Hockly, Emma, Richon, Victoria M., Woodman, Benjamin, Smith, Donna L., Zhou, Xianbo, Rosa, Eddie, Sathasivam, Kirupa, Ghazi-Noori, Shabnam, Mahal, Amarbirpal, Philip A. S. Lowden, Steffan, Joan S., Marsh, J. Lawrence, Thompson, Leslie M., Lewis, Cathryn M., Marks, Paul A., Bates, Gillian P.

“…Huntington's disease (HD) is an inherited, progressive neurological disorder that is caused by a CAG/polyglutamine repeat expansion and for which there is no…”
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The Huntington's Disease Protein Interacts with p53 and CREB-Binding Protein and Represses Transcription by Steffan, Joan S., Kazantsev, Aleksey, Spasic-Boskovic, Olivera, Greenwald, Marilee, Zhu, Ya-Zhen, Gohler, Heike, Wanker, Erich E., Bates, Gillian P., Housman, David E., Thompson, Leslie M.

“…Huntington's Disease (HD) is caused by an expansion of a polyglutamine tract within the huntingtin (htt) protein. Pathogenesis in HD appears to include the…”
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