Search Results - "Bates, Evelyn A."

Bilirubin Levels Are Negatively Correlated with Adiposity in Obese Men and Women, and Its Catabolized Product, Urobilin, Is Positively Associated with Insulin Resistance by Kipp, Zachary A, Xu, Mei, Bates, Evelyn A, Lee, Wang-Hsin, Kern, Philip A, Hinds, Jr, Terry D

“…Bilirubin levels in obese humans and rodents have been shown to be lower than in their lean counterparts. Some studies have proposed that the glucuronyl UGT1A1…”
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Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease by Bates, Evelyn A, Kipp, Zachary A, Martinez, Genesee J, Badmus, Olufunto O, Soundarapandian, Mangala M, Foster, Donald, Xu, Mei, Creeden, Justin F, Greer, Jennifer R, Morris, Andrew J, Stec, David E, Hinds, Jr, Terry D

“…Several population studies have observed lower serum bilirubin levels in patients with non-alcoholic fatty liver disease (NAFLD). Yet, treatments to target…”
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Loss of Carnitine Palmitoyltransferase 1a Reduces Docosahexaenoic Acid-Containing Phospholipids and Drives Sexually Dimorphic Liver Disease in Mice by Zelows, Mikala M., Cady, Corissa, Dharanipragada, Nikitha, Mead, Anna E., Kipp, Zachary A., Bates, Evelyn A., Varadharajan, Venkateshwari, Banerjee, Rakhee, Park, Se-Hyung, Shelman, Nathan R., Clarke, Harrison A., Hawkinson, Tara R., Medina, Terrymar, Sun, Ramon C., Lydic, Todd A., Hinds, Terry D., Brown, J. Mark, Softic, Samir, Graf, Gregory A., Helsley, Robert N.

“…Genome and epigenome wide association studies identified variants in carnitine palmitoyltransferase 1a (CPT1a) that associate with lipid traits. The goal of…”
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Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content by Kipp, Zachary A, Martinez, Genesee J, Bates, Evelyn A, Maharramov, Agil B, Flight, Robert M, Moseley, Hunter N B, Morris, Andrew J, Stec, David E, Hinds, Jr, Terry D

“…Studies have indicated that increasing plasma bilirubin levels might be useful for preventing and treating hepatic lipid accumulation that occurs with…”
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Loss of hepatic PPARα in mice causes hypertension and cardiovascular disease by Badmus, Olufunto O, Kipp, Zachary A, Bates, Evelyn A, da Silva, Alexandre A, Taylor, Lucy C, Martinez, Genesee J, Lee, Wang-Hsin, Creeden, Justin F, Hinds, Jr, Terry D, Stec, David E

“…The leading cause of death in patients with nonalcoholic fatty liver disease (NAFLD) is cardiovascular disease (CVD). However, the mechanisms are unknown. Mice…”
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FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells by Bates, Evelyn A., Kipp, Zachary A., Lee, Wang-Hsin, Martinez, Genesee J., Weaver, Lauren, Becker, Kathryn N., Pauss, Sally N., Creeden, Justin F., Anspach, Garrett B., Helsley, Robert N., Xu, Mei, Bruno, Maria E.C., Starr, Marlene E., Hinds, Terry D.

“…Liver fibrosis commences with liver injury stimulating transforming growth factor beta (TGFβ) activation of hepatic stellate cells (HSCs), causing scarring and…”
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Glucocorticoid resistance remodels liver lipids and prompts lipogenesis, eicosanoid, and inflammatory pathways by Martinez, Genesee J., Kipp, Zachary A., Lee, Wang-Hsin, Bates, Evelyn A., Morris, Andrew J., Marino, Joseph S., Hinds, Terry D.

“…We have previously demonstrated that the glucocorticoid receptor β (GRβ) isoform induces hepatic steatosis in mice fed a normal chow diet. The GRβ isoform…”
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Knockdown of Ketohexokinase Versus Inhibition of Its Kinase Activity Exert Divergent Effects on Fructose Metabolism by Park, Se-Hyung, Fadhul, Taghreed, Conroy, Lindsey R, Clarke, Harrison A, Sun, Ramon C, Wallenius, Kristina, Boucher, Jeremie, O'Mahony, Gavin, Boianelli, Alessandro, Persson, Marie, Jung, Sunhee, Jang, Cholsoon, Loria, Analia S, Martinez, Genesee J, Kipp, Zachary A, Bates, Evelyn A, Hinds, Jr, Terry D, Divanovic, Senad, Softic, Samir

“…Excessive fructose intake is a risk factor for the development of obesity and its complications. Targeting ketohexokinase (KHK), the first enzyme of fructose…”
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