Search Results - "Bates, Chris"

Development and validation of an electronic frailty index using routine primary care electronic health record data by Clegg, Andrew, Bates, Chris, Young, John, Ryan, Ronan, Nichols, Linda, Ann Teale, Elizabeth, Mohammed, Mohammed A, Parry, John, Marshall, Tom

“…frailty is an especially problematic expression of population ageing. International guidelines recommend routine identification of frailty to provide…”
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HIV infection and COVID-19 death: a population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform by Bhaskaran, Krishnan, Rentsch, Christopher T, MacKenna, Brian, Schultze, Anna, Mehrkar, Amir, Bates, Chris J, Eggo, Rosalind M, Morton, Caroline E, Bacon, Sebastian C J, Inglesby, Peter, Douglas, Ian J, Walker, Alex J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Forbes, Harriet J, Curtis, Helen J, Hulme, William J, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen J W, Smeeth, Liam, Goldacre, Ben

“…Whether HIV infection is associated with risk of death due to COVID-19 is unclear. We aimed to investigate this association in a large-scale population-based…”
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Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February by Grint, Daniel J, Wing, Kevin, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Evans, Stephen Jw, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Ys, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, Blomquist, Paula, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Goldacre, Ben, Smeeth, Liam, Eggo, Rosalind M

“…The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is…”
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Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform by Bhaskaran, Krishnan, Bacon, Sebastian, Evans, Stephen JW, Bates, Chris J, Rentsch, Christopher T, MacKenna, Brian, Tomlinson, Laurie, Walker, Alex J, Schultze, Anna, Morton, Caroline E, Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M, Inglesby, Peter, Douglas, Ian J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Curtis, Helen J, Hulme, William J, Parry, John, Hester, Frank, Harper, Sam, Spiegelhalter, David, Smeeth, Liam, Goldacre, Ben

“…Mortality from COVID-19 shows a strong relationship with age and pre-existing medical conditions, as does mortality from other causes. We aimed to investigate…”
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Diet quality is associated with all-cause mortality in adults aged 65 years and older by McNaughton, Sarah A, Bates, Chris J, Mishra, Gita D

“…Diet quality indices assess compliance with dietary guidelines and represent a measure of healthy dietary patterns. Few studies have compared different…”
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Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England by Grint, Daniel J, Wing, Kevin, Houlihan, Catherine, Gibbs, Hamish P, Evans, Stephen J W, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Y S, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Smeeth, Liam, Goldacre, Ben, Eggo, Rosalind M

“…Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) alpha variant (B.1.1.7) is associated with higher transmissibility than…”
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Healthcare utilisation in people with long COVID: an OpenSAFELY cohort study by Lin, Liang-Yu, Henderson, Alasdair D, Carlile, Oliver, Dillingham, Iain, Butler-Cole, Ben F C, Marks, Michael, Briggs, Andrew, Jit, Mark, Tomlinson, Laurie A, Bates, Chris, Parry, John, Bacon, Sebastian C J, Goldacre, Ben, Mehrkar, Amir, MacKenna, Brian, Eggo, Rosalind M, Herrett, Emily

“…Long COVID potentially increases healthcare utilisation and costs. However, its impact on the NHS remains to be determined. This study aims to assess the…”
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Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY by Green, Amelia, Curtis, Helen, Hulme, William, Williamson, Elizabeth, McDonald, Helen, Bhaskaran, Krishnan, Rentsch, Christopher, Schultze, Anna, MacKenna, Brian, Mahalingasivam, Viyaasan, Tomlinson, Laurie, Walker, Alex, Fisher, Louis, Massey, Jon, Andrews, Colm, Hopcroft, Lisa, Morton, Caroline, Croker, Richard, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Evans, David, Inglesby, Peter, Hickman, George, Ward, Tom, Davy, Simon, Mathur, Rohini, Tazare, John, Eggo, Rosalind, Wing, Kevin, Wong, Angel, Forbes, Harriet, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Evans, Stephen, Smeeth, Liam, Goldacre, Ben

“…While the vaccines against COVID-19 are highly effective, COVID-19 vaccine breakthrough is possible despite being fully vaccinated. With SARS-CoV-2 variants…”
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The Epidemiology of Chickenpox in England, 2016-2022: An Observational Study Using General Practitioner Consultations by Bardsley, Megan, Loveridge, Paul, Bednarska, Natalia G, Smith, Sue, Morbey, Roger A, Amirthalingam, Gayatri, Elson, William H, Bates, Chris, de Lusignan, Simon, Todkill, Daniel, Elliot, Alex J

“…Chickenpox is a common childhood disease caused by varicella-zoster virus (VZV). VZV vaccination is not part of the UK childhood immunisation programme, but…”
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Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients' records at source using OpenSAFELY by Andrews, Colm D, Mathur, Rohini, Massey, Jon, Park, Robin, Curtis, Helen J, Hopcroft, Lisa, Mehrkar, Amir, Bacon, Seb, Hickman, George, Smith, Rebecca, Evans, David, Ward, Tom, Davy, Simon, Inglesby, Peter, Dillingham, Iain, Maude, Steven, O'Dwyer, Thomas, Butler-Cole, Ben F C, Bridges, Lucy, Bates, Chris, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, Goldacre, Ben, MacKenna, Brian, Tomlinson, Laurie A, Walker, Alex J, Hulme, William J

“…Ethnicity is known to be an important correlate of health outcomes, particularly during the COVID-19 pandemic, where some ethnic groups were shown to be at…”
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Utilising primary care electronic health records to deliver the ALABAMA randomised controlled trial of penicillin allergy assessment by Ahmed, Shadia, Fielding, Joanne, Porter, Catherine E, Armitage, Kelsey F, Wanat, Marta, Bates, Chris, Engonidou, Lazarina, West, Robert M, Yu, Ly-Mee, Galal, Ushma, Howard, Philip, Butler, Christopher C, Savic, Sinisa, Boards, Jenny, Tonkin-Crine, Sarah, Parry, John, Pavitt, Sue A, Sandoe, Jonathan T

“…Use of electronic health records (EHR) to provide real-world data for research is established, but using EHR to deliver randomised controlled trials (RCTs)…”
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MULTIPLE HEALTH BEHAVIORS AND MORTALITY RISK IN OLDER ADULTS by Hamer, Mark, Bates, Chris J., Mishra, Gita D.

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Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65 by Schultze, Anna, Nightingale, Emily, Evans, David, Hulme, William, Rosello, Alicia, Bates, Chris, Cockburn, Jonathan, MacKenna, Brian, Curtis, Helen J, Morton, Caroline E, Croker, Richard, Bacon, Seb, McDonald, Helen I, Rentsch, Christopher T, Bhaskaran, Krishnan, Mathur, Rohini, Tomlinson, Laurie A, Williamson, Elizabeth J, Forbes, Harriet, Tazare, John, Grint, Daniel, Walker, Alex J, Inglesby, Peter, DeVito, Nicholas J, Mehrkar, Amir, Hickman, George, Davy, Simon, Ward, Tom, Fisher, Louis, Green, Amelia CA, Wing, Kevin, Wong, Angel YS, McManus, Robert, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen JW, Douglas, Ian J, Smeeth, Liam, Eggo, Rosalind M, Goldacre, Ben, Leon, David A

“…Residents in care homes have been severely impacted by COVID-19. We describe trends in the mortality risk among residents of care homes compared to private…”
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Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic: an efficient cluster randomised controlled trial using the OpenSAFELY platform by Ainsworth, Ben, Horwood, Jeremy, Walter, Scott R, Miller, Sascha, Chalder, Melanie, De Vocht, Frank, Denison-Day, James, Elwenspoek, Martha M C, Curtis, Helen J, Bates, Chris, Mehrkar, Amir, Bacon, Seb, Goldacre, Ben, Craggs, Pippa, Amlôt, Richard, Francis, Nick, Little, Paul, Macleod, John, Moore, Michael, Morton, Kate, Rice, Cathy, Sterne, Jonathan, Stuart, Beth, Towler, Lauren, Willcox, Merlin L, Yardley, Lucy

“…Germ Defence ( www.germdefence.org ) is an evidence-based interactive website that promotes behaviour change for infection control within households. To…”
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Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults' primary care records in England through OpenSAFELY by Fisher, Louis, Curtis, Helen J, Croker, Richard, Wiedemann, Milan, Speed, Victoria, Wood, Christopher, Brown, Andrew, Hopcroft, Lisa E M, Higgins, Rose, Massey, Jon, Inglesby, Peter, Morton, Caroline E, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Hickman, George, Macdonald, Orla, Lewis, Tom, Wood, Marion, Myers, Martin, Samuel, Miriam, Conibere, Robin, Baqir, Wasim, Sood, Harpreet, Drury, Charles, Collison, Kiren, Bates, Chris, Evans, David, Dillingham, Iain, Ward, Tom, Davy, Simon, Smith, Rebecca M, Hulme, William, Green, Amelia, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, O'Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, MacKenna, Brian, Goldacre, Ben

“…The COVID-19 pandemic has had a significant impact on delivery of NHS care. We have developed the OpenSAFELY Service Restoration Observatory (SRO) to develop…”
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Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study by Wong, Angel Y S, Tomlinson, Laurie A, Brown, Jeremy P, Elson, William, Walker, Alex J, Schultze, Anna, Morton, Caroline E, Evans, David, Inglesby, Peter, MacKenna, Brian, Bhaskaran, Krishnan, Rentsch, Christopher T, Powell, Emma, Williamson, Elizabeth, Croker, Richard, Bacon, Seb, Hulme, William, Bates, Chris, Curtis, Helen J, Mehrkar, Amir, Cockburn, Jonathan, McDonald, Helen I, Mathur, Rohini, Wing, Kevin, Forbes, Harriet, Eggo, Rosalind M, Evans, Stephen J W, Smeeth, Liam, Goldacre, Ben, Douglas, Ian J

“…Thromboembolism has been reported as a consequence of severe COVID-19. Although warfarin is a commonly used anticoagulant, it acts by antagonising vitamin K,…”
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Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform by Bhaskaran, Krishnan, Rentsch, Christopher T, Hickman, George, Hulme, William J, Schultze, Anna, Curtis, Helen J, Wing, Kevin, Warren-Gash, Charlotte, Tomlinson, Laurie, Bates, Chris J, Mathur, Rohini, MacKenna, Brian, Mahalingasivam, Viyaasan, Wong, Angel, Walker, Alex J, Morton, Caroline E, Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M, Inglesby, Peter, Douglas, Ian J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen Jw, Bacon, Sebastian, Smeeth, Liam, Goldacre, Ben

“…There is concern about medium to long-term adverse outcomes following acute Coronavirus Disease 2019 (COVID-19), but little relevant evidence exists. We aimed…”
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OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic by Curtis, Helen J, MacKenna, Brian, Walker, Alex J, Croker, Richard, Mehrkar, Amir, Morton, Caroline, Bacon, Seb, Hickman, George, Inglesby, Peter, Bates, Chris, Evans, David, Ward, Tom, Cockburn, Jonathan, Davy, Simon, Bhaskaran, Krishnan, Schultze, Anna, Rentsch, Christopher T, Williamson, Elizabeth, Hulme, William, Tomlinson, Laurie, Mathur, Rohini, Drysdale, Henry, Eggo, Rosalind M, Wong, Angel Yun, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Smeeth, Liam, Goldacre, Ben

“…BackgroundEarly in the COVID-19 pandemic, the National Health Service (NHS) recommended that appropriate patients anticoagulated with warfarin should be…”
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Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY by Wiedemann, Milan, Speed, Victoria, Cunningham, Christine, Higgins, Rose, Curtis, Helen J, Andrews, Colm, Fisher, Louis, Hopcroft, Lisa, Rentsch, Christopher T, Mahalingasivam, Viyaasan, Tomlinson, Laurie, Morton, Caroline, Samuel, Miriam, Green, Amelia, Wood, Christopher, Brown, Andrew D, Massey, Jon, Walters, Caroline, Smith, Rebecca M, Inglesby, Peter, Evans, David, Maude, Steven, Dillingham, Iain, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, McManus, Richard J, Goldacre, Ben, MacKenna, Brian

“…BackgroundThe COVID-19 pandemic disrupted cardiovascular disease management in primary care in England.ObjectiveTo describe the impact of the pandemic on blood…”
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Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP by Cunningham, Christine, Fisher, Louis, Wood, Christopher, Speed, Victoria, Brown, Andrew D, Curtis, Helen, Higgins, Rose, Croker, Richard, Butler-Cole, Ben FC, Evans, David, Inglesby, Peter, Dillingham, Iain, Bacon, Sebastian CJ, Beech, Elizabeth, Hand, Kieran, Davy, Simon, Ward, Tom, Hickman, George, Bridges, Lucy, O'Dwyer, Thomas, Maude, Steven, Smith, Rebecca M, Mehrkar, Amir, Hart, Liam C, Bates, Chris, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Goldacre, Ben, MacKenna, Brian

“…ObjectiveTo investigate the effect of the covid-19 pandemic on the number of patients with group A streptococcal infections and related antibiotic…”
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