Search Results - "Batchelor, A M"

A viable isolated tissue system: A tool for detailed MR measurements and controlled perturbation in physiologically stable tissue by Richardson, S., Siow, B., Batchelor, A. M., Lythgoe, M. F., Alexander, D. C.

“…In vivo magnetic resonance imaging (MRI) assessment of neuronal tissue is prone to artifacts such as movement, pulsatile flow, and tissue susceptibility…”
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Nitric oxide toxicity in CNS white matter: an in vitro study using rat optic nerve by Garthwaite, G, Goodwin, D.A, Batchelor, A.M, Leeming, K, Garthwaite, J

“…Excessive nitric oxide formation may contribute to the pathology occurring in diseases affecting central white matter, such as multiple sclerosis. The rat…”
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Potent and specific action of the mGlu1 antagonists YM‐298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices by Fukunaga, I, Yeo, C H, Batchelor, A M

“…Background and purpose: Specific and selective inhibitors for mGlu1 receptors are presently inadequate. A new generation of non‐competitive mGlu1 antagonists…”
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Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway by Batchelor, Andrew M, Garthwaite, John

“…In the classical view, a central neuron integrates incoming synaptic information by simple algebraic summation of the resultant bioelectrical signals that…”
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Synaptic activation of metabotropic glutamate receptors in the parallel fibre-Purkinje cell pathway in rat cerebellar slices by Batchelor, A M, Madge, D J, Garthwaite, J

“…Glutamate, the major excitatory neurotransmitter in the central nervous system, acts through two broad classes of receptors: ion channel-linked (ionotropic)…”
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TISS and mortality after discharge from intensive care by SMITH, L, ORTS, C. M, O'NEIL, I, BATCHELOR, A. M, GASCOIGNE, A. D, BAUDOUIN, S. V

“…To examine the effect of high levels of pre-intensive care unit (ICU) discharge care, as assessed by the Therapeutic Intervention Scoring System (TISS), on…”
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Mechanisms of ischaemic damage to central white matter axons: a quantitative histological analysis using rat optic nerve by Garthwaite, G., Brown, G., Batchelor, A.M., Goodwin, D.A., Garthwaite, J.

“…The mechanism of ischaemic injury to white matter axons was studied by transiently depriving rat optic nerves in vitro of oxygen and glucose. Light and…”
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Novel action of BAPTA series chelators on intrinsic K+ currents in rat hippocampal neurones by Lancaster, B., Batchelor, A. M.

“…Whole-cell recordings were made from rat CA1 neurones in brain slices. When electrodes contained diazo-2 (2 m m ) or dibromo BAPTA (1 m m ) a large…”
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Pharmacological Characterization of Synaptic Transmission through mGluRs in Rat Cerebellar Slices by BATCHELOR, A.M, KNÖPFEL, T, GASPARINI, F, GARTHWAITE, J

“…The mGluR-mediated EPSP at parallel fibre-Purkinje cell synapses in the cerebellum was blocked concentration-dependently and reversibly by antagonists acting…”
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Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis by Garthwaite, G., Batchelor, A. M., Goodwin, D. A., Hewson, A. K., Leeming, K., Ahmed, Z., Cuzner, M. L., Garthwaite, J.

“…Excessive nitric oxide (NO) production from the inducible isoform of nitric oxide synthase (iNOS) has been invoked as a causative factor in many…”
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Regulation of synaptic transmission in the mossy fibre-granule cell pathway of rat cerebellum by metabotropic glutamate receptors by Vetter, P, Garthwaite, J, Batchelor, A.M

“…The role of metabotropic glutamate receptors (mGluRs) in the mossy fibre-granule cell pathway in rat cerebellum was studied using slice preparations and…”
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Sleep-related breathing disorders following discharge from intensive care by CHISHTI, A, BATCHELOR, A. M, BULLOCK, R. E, FULTON, B, GASCOIGNE, A. D, BAUDOUIN, S. V

“…To determine the incidence of sleep-related breathing disorders and nocturnal hypoxaemia in patients discharged from ICU following prolonged mechanical…”
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Training and assessment of competency in the transfer of critically ill patients by Cosgrove, J. F., Kilner, A. J., Batchelor, A. M., Clarke, F., Bonner, S., Mensah, J.

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Novel synaptic potentials in cerebellar Purkinje cells: probable mediation by metabotropic glutamate receptors by Batchelor, A M, Garthwaite, J

“…Glutamate receptors of both the ionotropic (ion channel-linked) and metabotropic (enzyme-linked) categories are abundantly expressed by Purkinje cells in the…”
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A biplanar slice preparation for studying cerebellar synaptic transmission by Garthwaite, John, Batchelor, Andrew M.

“…Unlike certain other brain areas, notably the hippocampal formation, synaptic transmission in the cerebellum, a 3-dimensional anatomical structure, is not…”
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Selective blockade of N-methyl-D-aspartate receptor function by the nitric oxide donor, nitroprusside by East, S J, Batchelor, A M, Garthwaite, J

“…The N-methyl-D-aspartate (NMDA) receptor-mediated component of the synaptic response of cerebellar granule cells to mossy fibre stimulation was selectively…”
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Robertshaw double lumen tubes : a reappraisal thirty years on by CONACHER, I. D, HERREMA, I. H, BATCHELOR, A. M

“…A prospective analysis of 100 successive intubations with Robertshaw tubes in patients submitted for routine thoracic surgery is presented. Clinical guidelines…”
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The synaptic potential mediated by metabotropic glutamate receptors is not associated with a substantial elevation of cytosolic free calcium concentration in Purkinje cells by Batchelor, A M, Vranesic, I, Del Principe, F, Garthwaite, J, Knöpfel, T

“…Brief tetanic stimulation of parallel fibres can evoke a slow excitatory postsynaptic potential (EPSP) in cerebellar Purkinje cells that is mediated by…”
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Anaphylactoid or carcinoid? by Batchelor, A M, Conacher, I D

“…A patient with a carcinoid tumour and a history suggestive of carcinoid syndrome, but with no biochemical evidence in support, had a cardiovascular collapse…”
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Metabotropic glutamate receptor subtypes modulating neurotransmission at parallel fibre–Purkinje cell synapses in rat cerebellum by Neale, Stuart A., Garthwaite, John, M. Batchelor, Andrew

“…The actions of reportedly group-selective metabotropic glutamate (mGlu) receptor agonists and antagonists on neurotransmission at parallel fibre–Purkinje cell…”
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