Search Results - "Batchelder, Erika M"
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The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
Published in Cell research (01-01-2012)“…Metabolism is vital to every aspect of cell function, yet the metabolome of induced pluripotent stem cells (iPSCs) remains largely unexplored. Here we report,…”
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Differential requirements for clathrin-dependent endocytosis at sites of cell-substrate adhesion
Published in Molecular biology of the cell (01-09-2010)“…Clathrin-dependent endocytosis is a major route for the cellular import of macromolecules and occurs at the interface between the cell and its surroundings…”
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Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (02-10-2012)“…Generation of human induced pluripotent stem cells (hiPSCs) by the expression of specific transcription factors depends on successful epigenetic reprogramming…”
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Rapid and highly efficient generation of induced pluripotent stem cells from human umbilical vein endothelial cells
Published in PloS one (16-05-2011)“…The ability to induce somatic cells to pluripotency by ectopic expression of defined transcription factors (e.g. KLF-4, OCT4, SOX2, c-MYC, or KOSM) has…”
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Generation of a Drug-inducible Reporter System to Study Cell Reprogramming in Human Cells
Published in The Journal of biological chemistry (23-11-2012)“…Reprogramming of somatic cells into induced pluripotent stem cells is achieved by the expression of defined transcription factors. In the last few years,…”
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Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming
Published in Nature communications (01-01-2013)“…Recent studies indicate that human-induced pluripotent stem cells contain genomic structural variations and point mutations in coding regions. However, these…”
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7
Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (02-10-2012)“…Generation of human induced pluripotent stem cells (hiPSCs) by the expression of specific transcription factors depends on successful epigenetic reprogramming…”
Get full text
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