Search Results - "Batabyal Subrata"

Sensitization of ON-bipolar cells with ambient light activatable multi-characteristic opsin rescues vision in mice by Batabyal, Subrata, Gajjeraman, Sivakumar, Pradhan, Sanjay, Bhattacharya, Sulagna, Wright, Weldon, Mohanty, Samarendra

“…Gene therapy-based treatment such as optogenetics offers a potentially powerful way to bypass damaged photoreceptors in retinal degenerative diseases and use…”
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OCT guided micro-focal ERG system with multiple stimulation wavelengths for characterization of ocular health by Carlson, Michael, Kim, Sanghoon, Aparicio-Domingo, Silvia, Li, Kang V., Puig, Ben, Batabyal, Subrata, Canto-Soler, M. Valeria, Mohanty, Samarendra

“…Inherited retinal disorders and dry age-related macular degeneration are characterized by the degeneration and death of different types of photoreceptors at…”
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Publisher Correction: OCT guided micro-focal ERG system with multiple stimulation wavelengths for characterization of ocular health by Carlson, Michael, Kim, Sanghoon, Aparicio-Domingo, Silvia, Li, Kang V., Puig, Ben, Batabyal, Subrata, Canto-Soler, M. Valeria, Mohanty, Samarendra

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Engineered sensor actuator modulator as aqueous humor outflow actuator for gene therapy of primary open-angle glaucoma by Mohanty, Samarendra, Batabyal, Subrata, Idigo, Chinenye, Narcisse, Darryl, Kim, Sanghoon, Al-Saad, Houssam, Carlson, Michael, Tchedre, Kissaou, Dibas, Adnan

“…Glaucoma, a blinding eye disease with optic neuropathy, is usually associated with elevated intraocular pressure (IOP). The currently available pharmacological…”
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Response of heterologously expressed pressure sensor-actuator-modulator macromolecule to external mechanical stress by Batabyal, Subrata, Idigo, Chinenye, Narcisse, Darryl, Dibas, Adnan, Mohanty, Samarendra

“…Cells from different organs in the body experience a range of mechanical and osmotic pressures that change in various diseases, including neurological,…”
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Biodistribution of adeno‐associated virus type 2 carrying multi‐characteristic opsin in dogs following intravitreal injection by Tchedre, Kissaou T., Batabyal, Subrata, Galicia, Melissa, Narcisse, Darryl, Mustafi, Sourajit Mitra, Ayyagari, Ananta, Chavala, Sai, Mohanty, Samarendra K.

“…Gene therapy of retinal diseases using recombinant adeno‐associated virus (rAAV) vector‐based delivery has shown clinical success, and clinical trials based on…”
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Monitoring Visual Cortical Activities During Progressive Retinal Degeneration Using Functional Bioluminescence Imaging by Narcisse, Darryl, Mustafi, Sourajit M, Carlson, Michael, Kim, Sanghoon, Batabyal, Subrata, Wright, Weldon, Mohanty, Samarendra K

“…Mouse models of inherited retinal degenerative diseases such as retinitis pigmentosa are characterized by degeneration of photoreceptors, which hinders the…”
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Bioluminescent Multi-Characteristic Opsin for Simultaneous Optical Stimulation and Continuous Monitoring of Cortical Activities by Narcisse, Darryl, Mustafi, Sourajit Mitra, Carlson, Michael, Batabyal, Subrata, Kim, Sanghoon, Wright, Weldon, Kumar Mohanty, Samarendra

“…Stimulation and continuous monitoring of neural activities at cellular resolution are required for the understanding of the sensory processing of stimuli and…”
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Vitamin B2 in Nanoscopic Environments under Visible Light: Photosensitized Antioxidant or Phototoxic Drug? by Chaudhuri, Siddhi, Batabyal, Subrata, Polley, Nabarun, Pal, Samir Kumar

“…Vitamin B2 has been studied as a conventional antioxidant (in the dark) since its discovery in 1926. The effect of visible light on vitamin B2-containing food…”
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Near-Infrared Laser-Based Spatially Targeted Nano-enhanced Optical Delivery of Therapeutic Genes to Degenerated Retina by Batabyal, Subrata, Gajjeraman, Sivakumar, Tchedre, Kissaou, Dibas, Adnan, Wright, Weldon, Mohanty, Samarendra

“…Non-viral delivery of therapeutic genes into targeted areas of retina is essential for re-functionalizing the retinal circuitry. While a focused ultrafast…”
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Broad-Band Activatable White-Opsin by Batabyal, Subrata, Cervenka, Gregory, Ha, Ji Hee, Kim, Young-Tae, Mohanty, Samarendra

“…Currently, the use of optogenetic sensitization of retinal cells combined with activation/inhibition has the potential to be an alternative to retinal implants…”
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Optical delivery of multiple opsin-encoding genes leads to targeted expression and white-light activation by Dhakal, Kamal, Batabyal, Subrata, Wright, Weldon, Kim, Young-tae, Mohanty, Samarendra

“…In photodegenerative diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), progressive loss of vision occurs as a result of…”
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An improved microfluidics approach for monitoring real-time interaction profiles of ultrafast molecular recognition by Batabyal, Subrata, Rakshit, Surajit, Kar, Shantimoy, Pal, Samir Kumar

“…Our study illustrates the development of a microfluidics (MF) platform combining fluorescence microscopy and femtosecond/picosecond-resolved spectroscopy to…”
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Dynamical perspective of protein-DNA interaction by Batabyal Subrata, Choudhury Susobhan, Sao Dilip, Mondol Tanumoy, Kumar Pal Samir

“…The interactions between protein-DNA are essential for various biological activities. In this review, we provide an overview of protein-DNA interactions that…”
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Layer-specific nanophotonic delivery of therapeutic opsin-encoding genes into retina by Batabyal, Subrata, Kim, Sanghoon, Wright, Weldon, Mohanty, Samarendra

“…In recent time, gene therapy has proven to be a promising remedial approach for treating visual disorders either by replacement of nonfunctioning gene(s) or by…”
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Safety of intravitreally delivered AAV2 vector‐mediated multi‐characteristic opsin genetic construct in wild type beagle dogs by Mohanty, Samarendra, Batabyal, Subrata, Ayyagari, Ananta, Sharif, Najam A.

“…Background A novel adeno‐associated virus 2 (AAV2)‐carried multi‐characteristic opsin (MCO) (MCO‐010) is undergoing several clinical trials as a novel…”
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Ultrafast laser-assisted spatially targeted optoporation into cortical axons and retinal cells in the eye by Batabyal, Subrata, Kim, Young-Tae, Mohanty, Samarendra

“…Visualization and assessment of the cellular structure and function require localized delivery of the molecules into specific cells in restricted spatial…”
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Laser‐assisted targeted gene delivery to degenerated retina improves retinal function by Batabyal, Subrata, Kim, Sanghoon, Wright, Weldon, Mohanty, Samarendra

“…Delivery of therapeutic genes into retina is proving to reverse degeneration and restore vision, however, viral vector‐based gene delivery is prone to…”
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Pharmacologic fibroblast reprogramming into photoreceptors restores vision by Mahato, Biraj, Kaya, Koray Dogan, Fan, Yan, Sumien, Nathalie, Shetty, Ritu A., Zhang, Wei, Davis, Delaney, Mock, Thomas, Batabyal, Subrata, Ni, Aiguo, Mohanty, Samarendra, Han, Zongchao, Farjo, Rafal, Forster, Michael J., Swaroop, Anand, Chavala, Sai H.

“…Photoreceptor loss is the final common endpoint in most retinopathies that lead to irreversible blindness, and there are no effective treatments to restore…”
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Vitamin B 2 in Nanoscopic Environments under Visible Light: Photosensitized Antioxidant or Phototoxic Drug? by Chaudhuri, Siddhi, Batabyal, Subrata, Polley, Nabarun, Pal, Samir Kumar

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