Search Results - "Basudan, Ahmed"

Breast Cancer Incidence Patterns in the Saudi Female Population: A 17-Year Retrospective Analysis by Basudan, Ahmed M

“…Background and Objectives: Breast cancer is considered the most commonly diagnosed type of cancer among women globally and in Saudi Arabia. This study aimed to…”
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The Role of Immune Checkpoint Inhibitors in Cancer Therapy by Basudan, Ahmed M.

“…Over the years, immune checkpoint inhibitors (CPIs) have become a powerful treatment strategy in the field of cancer immunotherapy. In the last decade, the…”
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Epidemic dropsy toxin, sanguinarine chloride, stimulates sucrose-sensitive hemolysis and breakdown of membrane phospholipid asymmetry in human erythrocytes by Alfhili, Mohammad A., Alsughayyir, Jawaher, Basudan, Ahmed B.

“…Sanguinarine (SGN) is a benzophenathridine alkaloid extracted from Sanguinaria canadensis plant. SGN is incriminated in epidemic dropsy (ED) characterized by…”
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Geraniin inhibits whole blood IFN-γ and IL-6 and promotes IL-1β and IL-8, and stimulates calcium-dependent and sucrose-sensitive erythrocyte death by Alsughayyir, Jawaher, Alshaiddi, Wafa, Alsubki, Roua, Alshammary, Amal, Basudan, Ahmed M., Alfhili, Mohammad A.

“…Correlations between circulating cytokine levels and disease states are well established, and pharmacological modulation of the immune response is thus an…”
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Induction of hemolysis and eryptosis by occupational pollutant nickel chloride is mediated through calcium influx and p38 MAP kinase signaling by Alfhili, Mohammad A, Alamri, Hassan S, Alsughayyir, Jawaher, Basudan, Ahmed M

“…Nickel (Ni) is an abundant environmental hazard and an occupational pollutant. Exposure to Ni compounds is prevalent in electroplating workers and in the…”
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Physcion Induces Hemolysis and Premature Phosphatidylserine Externalization in Human Erythrocytes by Akiel, Maaged, Alsughayyir, Jawaher, Basudan, Ahmed M., Alamri, Hassan S., Dera, Ayed, Barhoumi, Tlili, Subayyil, Abdullah M. Al, Basmaeil, Yasser S., Aldakheel, Fahad M., Alakeel, Raid, Ghneim, Hazem K., Al-Sheikh, Yazeed A., Alraey, Yasser, Asiri, Saeed, Alfhili, Mohammad A.

“…The prevalence of cancer-associated anemia (CIA) is high, and the mechanisms governing its development remain poorly understood. Eryptosis, the suicidal cell…”
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Calcium-oxidative stress signaling axis and casein kinase 1α mediate eryptosis and hemolysis elicited by novel p53 agonist inauhzin by Alfhili, Mohammad A., Alsalmi, Essa, Aljedai, Abdullah, Alsughayyir, Jawaher, Abudawood, Manal, Basudan, Ahmed M.

“…Inauhzin (INZ) is a novel p53 agonist with antitumor activity. Anemia is a common side effect of chemotherapy and may arise from red blood cell (RBC) hemolysis…”
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Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets by Varešlija, Damir, Priedigkeit, Nolan, Fagan, Ailís, Purcell, Siobhan, Cosgrove, Nicola, O'Halloran, Philip J, Ward, Elspeth, Cocchiglia, Sinéad, Hartmaier, Ryan, Castro, Carlos A, Zhu, Li, Tseng, George C, Lucas, Peter C, Puhalla, Shannon L, Brufsky, Adam M, Hamilton, Ronald L, Mathew, Aju, Leone, Jose P, Basudan, Ahmed, Hudson, Lance, Dwyer, Róisín, Das, Sudipto, O'Connor, Darran P, Buckley, Patrick G, Farrell, Michael, Hill, Arnold D K, Oesterreich, Steffi, Lee, Adrian V, Young, Leonie S

“…Breast cancer brain metastases (BrMs) are defined by complex adaptations to both adjuvant treatment regimens and the brain microenvironment. Consequences of…”
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Antiproliferative Wnt inhibitor wogonin prevents eryptosis following ionophoric challenge, hyperosmotic shock, oxidative stress, and metabolic deprivation by Alfhili, Mohammad A., Basudan, Ahmed M., Alsughayyir, Jawaher

“…Anemia is a common complication of chemotherapy and may arise due to premature or suicidal death of red blood cells (RBCs). Prevention of RBC death thus lends…”
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Reprogramming of erythrocyte lifespan by NFκB‐TNFα naphthoquinone antagonist β‐lapachone is regulated by calcium overload and CK1α by Alfhili, Mohammad A., Alsughayyir, Jawaher, Basudan, Ahmed M.

“…The pathophysiology of chemotherapy‐associated anemia, prevalent in at least 75% of patients, remains difficult to establish. Chemotherapy‐related anemia is…”
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Association of the HALP Score with Dyslipidemia: A Large, Nationwide Retrospective Study by Alshuweishi, Yazeed, Basudan, Ahmed M, Alfaifi, Mohammed, Daghistani, Hussam, Alfhili, Mohammad A

“…Background and Objectives: Dyslipidemia is a major risk factor for cardiovascular disease (CVD). The identification of new biomarkers that may enhance the risk…”
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Bioymifi, a novel mimetic of TNF-related apoptosis-induced ligand (TRAIL), stimulates eryptosis by Alfhili, Mohammad A., Basudan, Ahmed M., Aljaser, Feda S., Dera, Ayed, Alsughayyir, Jawaher

“…Tumor necrosis factor-related apoptosis-induced ligand (TRAIL) is a cytokine that initiates apoptosis upon binding to death receptor 5 (DR5) on cancer cells…”
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Comprehensive Retrospective Analysis of Colorectal Cancer Incidence Patterns in Saudi Arabia by Basudan, Ahmed M, Basuwdan, Abdulrahman Mohammed, Abudawood, Manal, Farzan, Raed, Alfhili, Mohammad A

“…Colorectal cancer (CRC) is the commonest cancer in Saudi males and the third most common in Saudi females. Although CRC represents a major public health…”
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A Comprehensive Two-Decade Analysis of Lymphoma Incidence Patterns in Saudi Arabia by Basudan, Ahmed M, Althani, Mohammed, Abudawood, Manal, Farzan, Raed, Alshuweishi, Yazeed, Alfhili, Mohammad A

“…Lymphomas account for approximately 10% of all cancer cases among the Saudi population. Even when separated, Hodgkin lymphoma (HL) and non-Hodgkin lymphoma…”
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Cichorins D-F: Three New Compounds from Cichorium intybus and Their Biological Effects by Khan, Muhammad Farooq, Nasr, Fahd A, Noman, Omar M, Alyhya, Nouf Abdulaziz, Ali, Iftikhar, Saoud, Mohamad, Rennert, Robert, Dube, Mthandazo, Hussain, Wahid, Green, Ivan R, Basudan, Omer Ahmed M, Ullah, Riaz, Anazi, Shamsa Hilal, Hussain, Hidayat

“…L., (chicory) is employed in various traditional medicines to treat a wide range of diseases and disorders. In the current investigation, two new naphthalane…”
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Monocyte-Lymphocyte Ratio and Dysglycemia: A Retrospective, Cross-Sectional Study of the Saudi Population by Alfhili, Mohammad A, Alsughayyir, Jawaher, Basudan, Ahmed M, Alsubki, Roua, Alqahtani, Saleh, Awan, Zuhier A, Algethami, Mohammed R, Al-Sheikh, Yazeed A

“…Background: Abnormalities in fasting blood glucose (FBG) resulting in hypoglycemia (OG), impaired fasting glycemia (IFG), or hyperglycemia (HG) arise from…”
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Patterns of 25-Hydroxyvitamin D3, Calcium Status, and Anemia in the Saudi Population: A Cross-Sectional Study by Alfhili, Mohammad A, Basudan, Ahmed M, Alfaifi, Mohammed, Awan, Zuhier A, Algethami, Mohammed R, Alsughayyir, Jawaher

“…Emerging evidence suggests an intricate relationship between vitamin D, Ca , and inflammation-driven anemia. We, thus, investigated the patterns of serum…”
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Stimulation of calcium influx and CK1α by NF‐κB antagonist [6]‐Gingerol reprograms red blood cell longevity by Alamri, Hassan S., Alsughayyir, Jawaher, Akiel, Maaged, Al‐Sheikh, Yazeed A., Basudan, Ahmed M., Dera, Ayed, Barhoumi, Tlili, Basuwdan, Abdulrahman M., Alfhili, Mohammad A.

“…Chemotherapy‐induced anemia (CIA) is a major obstacle in cancer management. Although the mechanisms governing CIA are poorly understood, recent efforts have…”
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Reduced platelet-lymphocyte ratio in a Saudi population with impaired fasting glycemia and hyperglycemia by Alfhili, Mohammad A., Alsughayyir, Jawaher, Basudan, Ahmed, Alfaifi, Mohammed, Awan, Zuhier A., Algethami, Mohammed R., Al-Sheikh, Yazeed A.

“…Diabetes mellitus (DM) is an inflammatory disorder characterized by elevated fasting blood glucose (FBG) with life-threatening complications. However, the…”
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Novel Nuclear Localization of Fatty Acid Synthase Correlates with Prostate Cancer Aggressiveness by Madigan, Allison A, Rycyna, Kevin J, Parwani, Anil V, Datiri, Yeipyeng J, Basudan, Ahmed M, Sobek, Kathryn M, Cummings, Jessica L, Basse, Per H, Bacich, Dean J, O'Keefe, Denise S

“…Fatty acid synthase is up-regulated in a variety of cancers, including prostate cancer. Up-regulation of fatty acid synthase not only increases production of…”
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