Search Results - "Basu, Upamanyu"
-
1
An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses
Published in PLoS pathogens (01-08-2015)“…Adeno-associated viruses (AAV) have evolved to exploit the dynamic reorganization of host cell machinery during co-infection by adenoviruses and other helper…”
Get full text
Journal Article -
2
Negotiating peace in North-East India: asymmetric federalism at work
Published in Round table (London) (02-09-2024)Get full text
Journal Article -
3
Comment on "Virtues and limitations of Pittsburgh green for ozone detection" by C. C. Beltrán, E. A. Palmer, B. R. Buckley and F. Iza, Chem. Commun., 2015, 51, 1579
Published in Chemical communications (Cambridge, England) (07-03-2016)“…We previously developed Pittsburgh Green homoallyl ether to quantify trace ozone. Independently, problems were reported when the method was used for excess…”
Get more information
Journal Article -
4
Fluorogenic Probe Using a Mislow–Evans Rearrangement for Real‐Time Imaging of Hydrogen Peroxide
Published in Angewandte Chemie International Edition (28-09-2020)“…Hydrogen peroxide (H2O2) mediates the biology of wound healing, apoptosis, inflammation, etc. H2O2 has been fluorometrically imaged with protein‐ or…”
Get full text
Journal Article -
5
Total Synthesis of Meayamycin B
Published in Journal of organic chemistry (03-04-2020)“…Meayamycin B is currently the most potent modulator of the splicing factor 3b subunit 1 and used by dozens of research groups. However, current supply for this…”
Get full text
Journal Article -
6
Inhibition of Splicing Factor SF3B1: Evaluating Effects on Iron Metabolism in K562 and CD34+ Cells
Published in Blood (06-12-2014)“…Somatic mutations in the RNA splicing factor SF3B1 have been found in hematopoietic cells from patients with myelodysplastic syndrome. The association is…”
Get full text
Journal Article -
7
Development of a New Enantioselective Reduction of Ketone and Fluorogenic Detection of Hydrogen Peroxide
Published 01-01-2017“…Aberrant splicing related mutations are related to many diseases including cancers while reactive oxygen species (ROS) imbalance is linked to oxidative…”
Get full text
Dissertation -
8
41. U2 snRNP Spliceosome Proteins Block Recombinant AAV Vector Transduction
Published in Molecular therapy (01-05-2015)Get full text
Journal Article -
9
Abstract 4336: Spliceosome inhibition as a novel therapeutic option in acute leukemia
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Spliceosome targeting is a novel therapeutic strategy, showing promising results in solid tumors and hematological malignancies. Aberrant splicing of…”
Get full text
Journal Article -
10
An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses: e1005082
Published in PLoS pathogens (01-08-2015)“…Adeno-associated viruses (AAV) have evolved to exploit the dynamic reorganization of host cell machinery during co-infection by adenoviruses and other helper…”
Get full text
Journal Article -
11
Spliceosome Inhibitor Meayamycin B As a Novel Potential Chemotherapeutic Agent in ALL and AML
Published in Blood (06-12-2014)“…Introduction The process of pre-mRNA splicing is gaining attention as a contributor to anticancer drug resistance and as a promising novel therapeutic target…”
Get full text
Journal Article -
12
Fluorogenic Probe Using a Mislow–Evans Rearrangement for Real‐Time Imaging of Hydrogen Peroxide
Published in Angewandte Chemie (28-09-2020)“…Hydrogen peroxide (H2O2) mediates the biology of wound healing, apoptosis, inflammation, etc. H2O2 has been fluorometrically imaged with protein‐ or…”
Get full text
Journal Article