Search Results - "Basu, Ritwika S"

Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation by Basu, Ritwika S., Sherman, Michael B., Gagnon, Matthieu G.

“…During translation initiation, initiation factor 2 (IF2) holds initiator transfer RNA (fMet-tRNA i fMet ) in a specific orientation in the peptidyl (P) site of…”
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Structural Basis of Transcription Initiation by Bacterial RNA Polymerase Holoenzyme by Basu, Ritwika S., Warner, Brittany A., Molodtsov, Vadim, Pupov, Danil, Esyunina, Daria, Fernández-Tornero, Carlos, Kulbachinskiy, Andrey, Murakami, Katsuhiko S.

“…The bacterial RNA polymerase (RNAP) holoenzyme containing σ factor initiates transcription at specific promoter sites by de novo RNA priming, the first step of…”
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8-Oxoguanine DNA Glycosylase1 conceals oxidized guanine in nucleoprotein-associated RNA of respiratory syncytial virus by Pan, Lang, Wang, Ke, Hao, Wenjing, Xue, Yaoyao, Zheng, Xu, Basu, Ritwika S, Hazra, Tapas K, Islam, Azharul, Hosakote, Yashoda, Tian, Bing, Gagnon, Matthieu G, Ba, Xueqing, Boldogh, Istvan

“…Respiratory syncytial virus (RSV), along with other prominent respiratory RNA viruses such as influenza and SARS-CoV-2, significantly contributes to the global…”
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Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography by Basu, Ritwika S., Murakami, Katsuhiko S.

“…The challenge for structural biology is to understand atomic-level macromolecular motions during enzymatic reaction. X-ray crystallography can reveal high…”
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Mechanistic insights into the alternative ribosome recycling by HflXr by Seely, Savannah M, Basu, Ritwika S, Gagnon, Matthieu G

“…During stress conditions such as heat shock and antibiotic exposure, ribosomes stall on messenger RNAs, leading to inhibition of protein synthesis. To…”
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