Search Results - "Bastin, Mark E"
-
1
Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants
Published in Cerebral cortex (New York, N.Y. 1991) (01-08-2018)“…Abstract Sex differences in the human brain are of interest for many reasons: for example, there are sex differences in the observed prevalence of psychiatric…”
Get full text
Journal Article -
2
Ageing and brain white matter structure in 3,513 UK Biobank participants
Published in Nature communications (15-12-2016)“…Quantifying the microstructural properties of the human brain’s connections is necessary for understanding normal ageing and disease. Here we examine brain…”
Get full text
Journal Article -
3
Total MRI load of cerebral small vessel disease and cognitive ability in older people
Published in Neurobiology of aging (01-10-2015)“…Abstract Cerebral small vessel disease (SVD) may cause cognitive dysfunction. We tested the association between the combined presence of magnetic resonance…”
Get full text
Journal Article -
4
The effect of network thresholding and weighting on structural brain networks in the UK Biobank
Published in NeuroImage (Orlando, Fla.) (01-05-2020)“…Whole-brain structural networks can be constructed using diffusion MRI and probabilistic tractography. However, measurement noise and the probabilistic nature…”
Get full text
Journal Article -
5
Associations between vascular risk factors and brain MRI indices in UK Biobank
Published in European heart journal (21-07-2019)“…Abstract Aims Several factors are known to increase risk for cerebrovascular disease and dementia, but there is limited evidence on associations between…”
Get full text
Journal Article -
6
An epigenetic predictor of death captures multi-modal measures of brain health
Published in Molecular psychiatry (01-08-2021)“…Individuals of the same chronological age exhibit disparate rates of biological ageing. Consequently, a number of methodologies have been proposed to determine…”
Get full text
Journal Article -
7
DNA methylation and brain structure and function across the life course: A systematic review
Published in Neuroscience and biobehavioral reviews (01-06-2020)“…•60 studies of association between DNAm and human brain MRI were identified.•Differential DNAm is associated with brain structure and function throughout…”
Get full text
Journal Article -
8
Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA–DTI working group
Published in NeuroImage (Orlando, Fla.) (01-11-2013)“…The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium was set up to analyze brain measures and genotypes from multiple sites across the…”
Get full text
Journal Article -
9
Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data
Published in Scientific reports (17-07-2017)“…Previous reports of altered grey and white matter structure in Major Depressive Disorder (MDD) have been inconsistent. Recent meta-analyses have, however,…”
Get full text
Journal Article -
10
Brain connectivity changes underlying depression and fatigue in relapsing-remitting multiple sclerosis: A systematic review
Published in PloS one (29-03-2024)“…Multiple Sclerosis (MS) is an autoimmune disease affecting the central nervous system, characterised by neuroinflammation and neurodegeneration. Fatigue and…”
Get full text
Journal Article -
11
Association between preterm brain injury and exposure to chorioamnionitis during fetal life
Published in Scientific reports (01-12-2016)“…Preterm infants are susceptible to inflammation-induced white matter injury but the exposures that lead to this are uncertain. Histologic chorioamnionitis…”
Get full text
Journal Article -
12
General factors of white matter microstructure from DTI and NODDI in the developing brain
Published in NeuroImage (Orlando, Fla.) (01-07-2022)“…Preterm birth is closely associated with diffuse white matter dysmaturation inferred from diffusion MRI and neurocognitive impairment in childhood. Diffusion…”
Get full text
Journal Article -
13
Predicting sex, age, general cognition and mental health with machine learning on brain structural connectomes
Published in Human brain mapping (01-04-2023)“…There is an increasing expectation that advanced, computationally expensive machine learning (ML) techniques, when applied to large population‐wide…”
Get full text
Journal Article -
14
Processing speed and the relationship between Trail Making Test-B performance, cortical thinning and white matter microstructure in older adults
Published in Cortex (01-10-2017)“…Part B of the Trail Making Test (TMT-B) is widely used as a quick and easy to administer measure of executive dysfunction. The current study investigated the…”
Get full text
Journal Article -
15
Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data
Published in NeuroImage (Orlando, Fla.) (01-05-2015)“…The degree to which genetic factors influence brain connectivity is beginning to be understood. Large-scale efforts are underway to map the profile of genetic…”
Get full text
Journal Article Web Resource -
16
Diffusion tensor MRI tractography reveals increased fractional anisotropy (FA) in arcuate fasciculus following music-cued motor training
Published in Brain and cognition (01-08-2017)“…•The neuroplasticity effects of music-cued motor training were investigated.•Participants completed left-handed motor training with or without musical…”
Get full text
Journal Article -
17
Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age
Published in Nature communications (10-02-2020)“…Identifying biological correlates of late life cognitive function is important if we are to ascertain biomarkers for, and develop treatments to help reduce,…”
Get full text
Journal Article -
18
Strong intercorrelations among global graph-theoretic indices of structural connectivity in the human brain
Published in NeuroImage (Orlando, Fla.) (15-07-2023)“…•Global network metrics are used to measure organizational properties of the brain.•Many metrics are highly correlated with each other and with topology-free…”
Get full text
Journal Article -
19
Prenatal methadone exposure is associated with altered neonatal brain development
Published in NeuroImage clinical (01-01-2018)“…Methadone is used for medication-assisted treatment of heroin addiction during pregnancy. The neurodevelopmental outcome of children with prenatal methadone…”
Get full text
Journal Article -
20
A general factor of brain white matter integrity predicts information processing speed in healthy older people
Published in The Journal of neuroscience (02-06-2010)“…Human white matter integrity has been related to information processing speed, but it is unknown whether impaired integrity results from localized processes or…”
Get full text
Journal Article