Search Results - "Bast, D. J."

Selection of Bacillus anthracis isolates resistant to antibiotics by Athamna, A., Athamna, M., Abu-Rashed, N., Medlej, B., Bast, D. J., Rubinstein, E.

“…Objective: Long-term therapy for anthrax might induce antimicrobial resistance in Bacillus anthracis. The aim of the present study was to investigate the…”
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In vitro post-antibiotic effect of fluoroquinolones, macrolides, β-lactams, tetracyclines, vancomycin, clindamycin, linezolid, chloramphenicol, quinupristin/dalfopristin and rifampicin on Bacillus anthracis by Athamna, A., Athamna, M., Medlej, B., Bast, D. J., Rubinstein, E.

“…Objectives: The aim of this study was to investigate in vitro the post-antibiotic effect (PAE) of 19 antibacterial agents against two strains of Bacillus…”
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First Report of the Visceral Leishmaniasis Vector Phlebotomus martini (Diptera: Psychodidae) in Tanzania by Clark, J. W., Kioko, E., Odemba, N., Ngere, F., Kamanza, J., Oyugi, E., Kerich, G., Kimbita, E., Bast, J. D.

“…Phlebotomus martini is a known vector of visceral leishmaniasis caused by Leishmania donovani in sub-Saharan Africa. The disease is known to be endemic in…”
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Prevalence and Mechanisms of Macrolide Resistance in Clinical Isolates of Group A Streptococci from Ontario, Canada by DE AZAVEDO, J. C. S, YEUNG, R. H, BAST, D. J, DUNCAN, C. L, BORGIA, S. B, LOW, D. E

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Genetic Locus for Streptolysin S Production by Group A Streptococcus by NIZET, V, BEALL, B, BAST, D. J, DATTA, V, KILBURN, L, LOW, D. E, DE AZAVEDO, J. C. S

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Fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae : Contributions of type II topoisomerase mutations and efflux to levels of resistance by BAST, Darrin J, LOW, Donald E, DUNCAN, Carla L, KILBURN, Laurie, MANDELL, Lionel A, DAVIDSON, Ross J, DE AZAVEDO, Joyce C. S

“…We report on amino acid substitutions in the quinolone resistance-determining region of type II topisomerases and the prevalence of reserpine-inhibited efflux…”
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The identification of three biologically relevant globotriaosyl ceramide receptor binding sites on the Verotoxin 1 B subunit by Bast, D. J., Banerjee, L., Clark, C., Read, R. J., Brunton, J. L.

“…The Verotoxin 1 (VT1) B subunit binds to the glycosphingolipid receptor globotriaosylceramide (Gb3). Receptor‐binding specificity is associated with the…”
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Activity of BMS-284756, a Novel Des-Fluoro(6) Quinolone, against Staphylococcus aureus, Including Contributions of Mutations to Quinolone Resistance by LOW, D. E, MULLER, M, DUNCAN, C. L, WILLEY, B. M, DE AZAVEDO, J. C, MCGEER, A, KREISWIRTH, B. N, PONG-PORTER, S, BAST, D. J

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Streptococcus iniae Virulence Is Associated with a Distinct Genetic Profile by FULLER, Jeffrey D, BAST, Darrin J, NIZET, Victor, LOW, Donald E, DE AZAVEDO, Joyce C. S

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Murine antibody responses to the verotoxin 1 B subunit: demonstration of major histocompatibility complex dependence and an immunodominant epitope involving phenylalanine 30 by BAST, D. J, SANDHU, J, HOZUMI, N, BARBER, B, BRUNTON, J

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Short-Course Therapy of Gemifloxacin Effective Against Pneumococcal Pneumonia in Mice by Bast, D.J., Dresser, L., Duncan, C.L., Walker, S.E., Mandell, L.A., Low, D.E., De Azavedo, J.C.S.

“…Standard 7-14 day (d) courses of antimicrobial therapy for community-acquired pneumonia (CAP) are thought to have contributed to the emergence of resistant…”
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Toxicity and immunogenicity of a verotoxin 1 mutant with reduced globotriaosylceramide receptor binding in rabbits by BAST, D. J, BRUNTON, J. L, KARMALI, M. A, RICHARDSON, S. E

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Relative Potential for Selection of Quinolone-Resistance- Determining-Region Mutations in Streptococcus pneumoniae by Gemifloxacin, Gatifloxacin and Moxifloxacin by De Azavedo, J.C.S., Duncan, C.L., Kilburn, L., Downar, J., Kong, B., Lad, S., Low, D.E., Bast, D.J.

“…Serial passage of a clinical isolate of Streptococcus pneumoniae, in the presence of moxifloxacin, gatifloxacin or gemifloxacin, gave rise to resistant…”
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Interspecies Recombination Contributes Minimally to Fluoroquinolone Resistance in Streptococcus pneumoniae by BAST, Darrin J, DE AZAVEDO, Joyce C. S, TAM, Tiffany Y, KILBURN, Laurie, DUNCAN, Carla, MANDELL, Lionel A, DAVIDSON, Ross J, LOW, Donald E

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A Nosocomial Outbreak of Fluoroquinolone-Resistant Streptococcus pneumoniae by Weiss, Karl, Restieri, C., Gauthier, Richard, Laverdière, Michel, McGeer, Allison, Davidson, Ross J., Kilburn, Laurie, Bast, Darrin J., de Azavedo, Joyce, Low, Donald E.

“…Over the course of a 20-month period, in a hospital respiratory ward in which ciprofloxacin was often used as empirical antimicrobial therapy for lower…”
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Identification of a Streptolysin S-Associated Gene Cluster and Its Role in the Pathogenesis of Streptococcus iniae Disease by FULLER, Jeffrey D, CAMUS, Alvin C, DUNCAN, Carla L, NIZET, Victor, BAST, Darrin J, THUNE, Ronald L, LOW, Donald E, DE AZAVEDO, Joyce C. S

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Type II topoisomerase mutations in Bacillus anthracis associated with high-level fluoroquinolone resistance by Bast, Darrin J., Athamna, Abed, Duncan, Carla L., de Azavedo, Joyce C. S., Low, Donald E., Rahav, Galia, Farrell, David, Rubinstein, Ethan

“…Objectives: To identify and characterize the mechanisms of high-level fluoroquinolone resistance in two strains of Bacillus anthracis following serial passage…”
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Antipneumococcal Activity of Ertapenem Compared with Gatifloxacin in a Temperature-Sensitive Murine Model of Acute Pneumonia by De Azavedo, J.C.S., Dresser, L., Duncan, C.L., Walker, S.E., Low, D.E., Bast, D.J.

“…Fluoroquinolone-resistance among pneumococci is low; however the number of solates with a single ParC mutation has increased. Consequently, more potent agents…”
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Daily concentrations of gonadotrophins and prolactin in the serum of pregnant or lactating hamsters by Bast, J D, Greenwald, G S

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A comprehensive profile of peripheral progesterone levels in cyclic hamsters sequentially bled at 2-hr intervals by Bast, J D

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