Search Results - "Basson, Bruce"

Exenatide twice daily versus glimepiride for prevention of glycaemic deterioration in patients with type 2 diabetes with metformin failure (EUREXA): an open-label, randomised controlled trial by Gallwitz, Baptist, Prof, Guzman, Juan, MD, Dotta, Francesco, MD, Guerci, Bruno, MD, Simó, Rafael, MD, Basson, Bruce R, MSc, Festa, Andreas, MD, Kiljański, Jacek, MD, Sapin, Hélène, MSc, Trautmann, Michael, MD, Schernthaner, Guntram, Prof

“…Summary Background Glycaemic control deteriorates progressively over time in patients with type 2 diabetes. Options for treatment escalation remain…”
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Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial by Vincent, Jean-Louis, Angus, Derek C, Artigas, Antonio, Kalil, Andre, Basson, Bruce R, Jamal, Hassan H, Johnson, Gerald, Bernard, Gordon R

“…OBJECTIVETo assess morbidity in patients with severe sepsis managed with and without drotrecogin alfa (activated). DESIGNAnalysis of secondary end points in a…”
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Long-term olanzapine treatment : Weight change and weight-related health factors in schizophrenia by KINON, Bruce J, BASSON, Bruce R, GILMORE, Julie A, TOLLEFSON, Gary D

“…Weight change and the weight-related health factors of nonfasting serum glucose, serum cholesterol, and diastolic blood pressure levels were analyzed in…”
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Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia by Kerlin, Bryce A., Yan, S. Betty, Isermann, Berend H., Brandt, John T., Sood, Rashmi, Basson, Bruce R., Joyce, David E., Weiler, Hartmut, Dhainaut, Jean-Francois

“…Sepsis is associated with systemic inflammation, coagulopathy, and disrupted protein C (PC) pathway function. The effect of prothrombotic polymorphism, factor…”
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Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis by Angus, Derek C, Linde-Zwirble, Walter T, Clermont, Gilles, Ball, Daniel E, Basson, Bruce R, Ely, E Wesley, Laterre, Pierre-Francois, Vincent, Jean-Louis, Bernard, Gordon, van Hout, Ben

“…OBJECTIVETo assess the cost-effectiveness of drotrecogin alfa (activated) therapy, which was recently shown to reduce mortality in severe sepsis…”
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Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone by BASSON, Bruce R, KINON, Bruce J, TAYLOR, Cindy C, SZYMANSKI, Keith A, GILMORE, Julie A, TOLLEFSON, Gary D

“…Clinical factors predicting weight change in patients with schizophrenia and related disorders during acute treatment with the antipsychotic drugs olanzapine,…”
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Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial by DHAINAUT, Jean-Francois, LATERRE, Pierre-Francois, VINCENT, Jean-Louis, JANES, Jonathan M, BERNARD, Gordon R, ARTIGAS, Antonio, BAKKER, Jan, RIESS, Hanno, BASSON, Bruce R, CHARPENTIER, Julien, UTTERBACK, Barbara G

“…Based on the results of the PROWESS trial the European Agency for the Evaluation of Medicinal Products has recently approved drotrecogin alfa (activated) for…”
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The Effect of Raloxifene after Discontinuation of Long-Term Alendronate Treatment of Postmenopausal Osteoporosis by Michalská, Dana, Stepan, Jan J., Basson, Bruce R., Pavo, Imre

“…Objective: The aim of this study was to compare bone mineral density (BMD) and biochemical markers of bone turnover in patients receiving long-term alendronate…”
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Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis by Dhainaut, Jean-François, Yan, S Betty, Margolis, Benjamin D, Lorente, José A, Russell, James A, Freebairn, Ross C, Spapen, Herbert D, Riess, Hanno, Basson, Bruce, Johnson, 3rd, Gerald, Kinasewitz, Gary T

“…Drotrecogin alfa (activated) improved survival in patients with severe sepsis in PROWESS, a double-blind, study of 1690 adult patients randomized to…”
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Antipsychotic treatment and sexual functioning in first-time neuroleptic-treated schizophrenic patients by Bitter, István, Basson, Bruce R, Dossenbach, Martin R

“…The present study examined sexual functioning among first-time treated schizophrenia patients at the time that they initiated antipsychotic treatment, and…”
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Efficacy and Treatment Satisfaction with On-Demand Tadalafil (Cialis ®) in Men with Erectile Dysfunction by Skoumal, René, Chen, Juza, Kula, Krzysztof, Breza, Jan, Calomfirescu, Nicolae, Basson, Bruce R, Kopernicky, Vladimir

“…Objective: Tadalafil (Cialis ®) is an inhibitor of phosphodiesterase type 5, which mediates relaxation of vascular smooth muscle in the corpus cavernosum thus…”
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Effects of Once‐Daily Tadalafil on Treatment Satisfaction, Psychosocial Outcomes, Spontaneous Erections, and Measures of Endothelial Function in Men With Erectile Dysfunction But Naive to Phosphodiesterase Type 5 Inhibitors by Porst, Hartmut, Brock, Gerald B., Kula, Krzysztof, Moncada, Ignacio, Montorsi, Francesco, Basson, Bruce R., Kinchen, Kraig, Aversa, Antonio

“…: Previous studies established the efficacy of once‐daily tadalafil for men with erectile dysfunction. However, no trial has focused on the effects of such…”
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A randomized phase II trial of sequential gemcitabine plus vinorelbine followed by gemcitabine plus ifosfamide versus gemcitabine plus cisplatin in the treatment of chemo-naive patients with stages III and IV non-small cell lung cancer (NSCLC) by Grigorescu, Alexandru, Ciuleanu, Tudor, Firoiu, Elena, Muresan, Delia Ruta, Teodorescu, Gabriela, Basson, Bruce R

“…Summary Background Third-generation platinum-based combinations are established as first-line treatment for advanced non-small cell lung cancer (NSCLC)…”
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Strategies for switching from conventional antipsychotic drugs or risperidone to olanzapine by KINON, Bruce J, BASSON, Bruce R, GILMORE, Julie A, MALCOLM, Sandra, STAUFFER, Virginia L

“…This study compared the efficacy and safety of 4 therapeutically relevant strategies for switching clinically stable patients from a conventional antipsychotic…”
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Is there a real difference between the first onset of efficacy for atypical antipsychotic monotherapies in acute bipolar mania? by Treuer, Tamas, Basson, Bruce R

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The Comparative Peripheral Anticholinergic-Like Adverse Event Profiles of Olanzapine and Risperidone by Kennedy, John S., Bymaster, Frank P., Basson, Bruce R., Gilmore, Julie A., Tran, Pierre V.

“…OBJECTIVE: To test the hypothesis that reported in vitro muscarinic receptor affinity differences between olanzapine and risperidone would be reflected in…”
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Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569] by Kinasewitz, Gary T, Yan, S Betty, Basson, Bruce, Comp, Philip, Russell, James A, Cariou, Alain, Um, Suzane L, Utterback, Barbara, Laterre, Pierre-Francois, Dhainaut, Jean-François

“…PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis) was a phase III, randomized, double blind, placebo controlled,…”
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Is There a Real Difference Between the First Onset of Efficacy for Atypical Antipsychotic Monotherapies in Acute Bipolar Mania?/Dr. Keck Replies by Treuer, Tamas, Basson, Bruce R, Keck, Paul E

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Efficacy and Treatment Satisfaction with on-demand Tadalafil (Cialis®) in men with erectile dysfunction. Commentary by SKOUMAL, René, CHEN, Juza, KULA, Krzysztof, BREZA, Jan, CALOMFIRESCU, Nicolae, BASSON, Bruce R, KOPERNICK, Vladimir, MONTORSI, F

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Rapid reduction in hyperprolactinemia upon switching treatment to olanzapine from conventional antipsychotic drugs or risperidone by Kinon, Bruce J., Basson, Bruce, Wang, Jeff, Malcolm, Sandra K.

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