Search Results - "Bassil, AK"

Little or no ability of obestatin to interact with ghrelin or modify motility in the rat gastrointestinal tract by Bassil, A K, Häglund, Y, Brown, J, Rudholm, T, Hellström, P M, Näslund, E, Lee, K, Sanger, G J

“…Background and purpose: Obestatin, encoded by the ghrelin gene may inhibit gastrointestinal (GI) motility. This activity was re‐investigated. Experimental…”
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The relationship between the effects of short‐chain fatty acids on intestinal motility in vitro and GPR43 receptor activation by Dass, N. B., John, A. K., Bassil, A. K., Crumbley, C. W., Shehee, W. R., Maurio, F. P., Moore, G. B. T., Taylor, C. M., Sanger, G. J.

“…The G protein‐coupled receptors, GPR41 and GPR43, are activated by short‐chain fatty acids (SCFAs), with distinct rank order potencies. This study investigated…”
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Inhibition of colonic motility and defecation by RS‐127445 suggests an involvement of the 5‐HT 2B receptor in rodent large bowel physiology by Bassil, AK, Taylor, CM, Bolton, VJN, Gray, KM, Brown, JD, Cutler, L, Summerfield, SG, Bruton, G, Winchester, WJ, Lee, K, Sanger, GJ

“…Background:  5‐HT 2B receptors are localized within the myenteric nervous system, but their functions on motor/sensory neurons are unclear. To explore the role…”
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Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin by Dass, N.B, Munonyara, M, Bassil, A.K, Hervieu, G.J, Osbourne, S, Corcoran, S, Morgan, M, Sanger, G.J

“…The peptide hormone ghrelin is known to be present within stomach and, to a lesser extent, elsewhere in gut. Although reports suggest that gastric function may…”
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Prokineticin-2, motilin, ghrelin and metoclopramide: Prokinetic utility in mouse stomach and colon by Bassil, Anna K., Dass, Narinder B., Murray, Charles D., Muir, Alison, Sanger, Gareth J.

“…The ability of agents described as gastrointestinal prokinetics (prokineticin-2, [Nle 13]-motilin, ghrelin), to modulate nerve-mediated contractions of mouse…”
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Inhibition of colonic motility and defecation by RS‐127445 suggests an involvement of the 5‐HT2B receptor in rodent large bowel physiology by Bassil, AK, Taylor, CM, Bolton, VJN, Gray, KM, Brown, JD, Cutler, L, Summerfield, SG, Bruton, G, Winchester, WJ, Lee, K, Sanger, GJ

“…Background:  5‐HT2B receptors are localized within the myenteric nervous system, but their functions on motor/sensory neurons are unclear. To explore the role…”
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5‐HT 4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle by Cellek, S., John, A. K., Thangiah, R., Dass, N. B., Bassil, A. K., Jarvie, E. M., Lalude, O., Vivekanandan, S., Sanger, G. J.

“…Abstract  Previous studies have demonstrated mixed inhibitory and facilitatory effects of 5‐hydroxytryptamine‐4 (5‐HT 4 ) receptor agonists on electrical field…”
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