Search Results - "Bass, Steven H"

An improved ternary vector system for Agrobacterium-mediated rapid maize transformation by Anand, Ajith, Bass, Steven H., Wu, Emily, Wang, Ning, McBride, Kevin E., Annaluru, Narayana, Miller, Michael, Hua, Mo, Jones, Todd J.

“…Key message A simple and versatile ternary vector system that utilizes improved accessory plasmids for rapid maize transformation is described. This system…”
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Directed evolution of gene-shuffled IFN-α molecules with activity profiles tailored for treatment of chronic viral diseases by Brideau-Andersen, Amy D, Huang, Xiaojian, Sun, Siu-Chi Chang, Chen, Teddy T, Stark, Diane, Sas, Ian J, Zadik, Linda, Dawes, Glenn N, Guptill, Douglas R, McCord, Robert, Govindarajan, Sridhar, Roy, Ajoy, Yang, Shumin, Gao, Judy, Chen, Yong Hong, Skartved, Niels Jørgen Ø, Pedersen, Annette K, Lin, David, Locher, Christopher P, Rebbapragada, Indrani, Jensen, Anne Dam, Bass, Steven H, Nissen, Torben L. Straight, Viswanathan, Sridhar, Foster, Graham R, Symons, Julian A, Patten, Phillip A

“…Type I IFNs are unusually pleiotropic cytokines that bind to a single heterodimeric receptor and have potent antiviral, antiproliferative, and immune…”
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ASP2408 and ASP2409, novel CTLA4-Ig variants with CD86-selective ligand binding activity and improved immunosuppressive potency, created by directed evolution by Oshima, Shinsuke, Karrer, Erik E., Paidhungat, Madan M., Neighbors, Margaret, Chapin, Steven J., Fan, Rong A., Reed, Margaret A., Wu, Kuoting, Wong, Clifford, Chen, Yonghong, Whitlow, Marc, Anderson, Francisco A., Bam, Rujuta A., Zhang, Qian, Larsen, Brent R., Viswanathan, Sridhar, Devens, Bruce H., Bass, Steven H., Higashi, Yasuyuki

“…Abstract The CTLA4-Ig therapeutics abatacept and belatacept inhibit CD28-mediated T cell activation by binding CD80 (B7-1) and CD86 (B7-2) co-stimulatory…”
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Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor by de Vos, Abraham M, Wiesmann, Christian, Ultsch, Mark H, Bass, Steven H

“…Nerve growth factor (NGF) is involved in a variety of processes involving signalling, such as cell differentiation and survival, growth cessation and apoptosis…”
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Selecting high-affinity binding proteins by monovalent phage display by Lowman, Henry B, Bass, Steven H, Simpson, Nancy, Wells, James A

“…Variants of human growth hormone (hGH) with increased affinity and specificity for the hGH receptor were isolated using an improved phage display system…”
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Application of the E. coli trp promoter by BASS, Steven H, YANSURA, Daniel G

“…The Escherichia coli tryptophan (trp) promoter has been used extensively for the high level production of proteins on a small and large scale. This regulated…”
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Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC by Ultsch, M H, Wiesmann, C, Simmons, L C, Henrich, J, Yang, M, Reilly, D, Bass, S H, de Vos, A M

“…The Trk receptors and their neurotrophin ligands control development and maintenance of the nervous system. The crystal structures of the ligand binding domain…”
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A Systematic Mutational Analysis of Hormone-Binding Determinants in the Human Growth Hormone Receptor by Bass, Steven H., Mulkerrin, Michael G., Wells, James A.

“…A mutational strategy is presented that allowed us to identify hormone-binding determinants in the extracellular portion of the human growth hormone receptor…”
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Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC 1 1Edited by I. A. Wilson by Ultsch, Mark H, Wiesmann, Christian, Simmons, Laura C, Henrich, Jill, Yang, Maria, Reilly, Dorothea, Bass, Steven H, de Vos, Abraham M

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The molecular basis for growth hormone-receptor interactions by Wells, J A, Cunningham, B C, Fuh, G, Lowman, H B, Bass, S H, Mulkerrin, M G, Ultsch, M, deVos, A M

“…High-resolution mutational and structural analyses of purified components have revealed a great deal about the molecular basis for growth hormone action. The…”
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Neutrophil Adhesiveness During Prostacyclin and Heparin Hemodialysis by Spagnuolo, Philip J., Bass, Steven H., Smith, Michael C., Danviriyasup, Kowit, Dunn, Michael J.

“…We evaluated neutrophil adhesive function in patients undergoing chronic hemodialysis using either prostacyclin or heparin as antithrombotic agents. Patients…”
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