Search Results - "Baskin, David"

Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target by Abdelfattah, Nourhan, Kumar, Parveen, Wang, Caiyi, Leu, Jia-Shiun, Flynn, William F., Gao, Ruli, Baskin, David S., Pichumani, Kumar, Ijare, Omkar B., Wood, Stephanie L., Powell, Suzanne Z., Haviland, David L., Parker Kerrigan, Brittany C., Lang, Frederick F., Prabhu, Sujit S., Huntoon, Kristin M., Jiang, Wen, Kim, Betty Y. S., George, Joshy, Yun, Kyuson

“…A major rate-limiting step in developing more effective immunotherapies for GBM is our inadequate understanding of the cellular complexity and the molecular…”
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Obituary. Robert G. Grossman, MD, 1933-2021 by Britz, Gavin W, Baskin, David S

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MP-Pt(IV): A MAOB-Sensitive Mitochondrial-Specific Prodrug for Treating Glioblastoma by Raghavan, Sudhir, Baskin, David S, Sharpe, Martyn A

“…We have previously reported the and efficacy of N,N-bis(2-chloroethyl)-2-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)propenamide (MP-MUS), a prodrug that targeted…”
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Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells by Hambarde, Shashank, Manalo, Jeanne M., Baskin, David S., Sharpe, Martyn A., Helekar, Santosh A.

“…Raising reactive oxygen species (ROS) levels in cancer cells to cause macromolecular damage and cell death is a promising anticancer treatment strategy…”
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Combinational Targeting Offsets Antigen Escape and Enhances Effector Functions of Adoptively Transferred T Cells in Glioblastoma by Hegde, Meenakshi, Corder, Amanda, Chow, Kevin KH, Mukherjee, Malini, Ashoori, Aidin, Kew, Yvonne, Zhang, Yi Jonathan, Baskin, David S, Merchant, Fatima A, Brawley, Vita S, Byrd, Tiara T, Krebs, Simone, Wu, Meng Fen, Liu, Hao, Heslop, Helen E, Gottachalk, Stephen, Yvon, Eric, Ahmed, Nabil

“…Preclinical and early clinical studies have demonstrated that chimeric antigen receptor (CAR)-redirected T cells are highly promising in cancer therapy. We…”
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Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma by Wheeler, Lee A, Manzanera, Andrea G, Bell, Susan D, Cavaliere, Robert, McGregor, John M, Grecula, John C, Newton, Herbert B, Lo, Simon S, Badie, Behnam, Portnow, Jana, Teh, Bin S, Trask, Todd W, Baskin, David S, New, Pamela Z, Aguilar, Laura K, Aguilar-Cordova, Estuardo, Chiocca, E Antonio

“…Despite aggressive standard of care (SOC) treatment, survival of malignant gliomas remains very poor. This Phase II, prospective, matched controlled,…”
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Acquisition of Immune Privilege in GBM Tumors: Role of Prostaglandins and Bile Salts by Sharpe, Martyn A, Baskin, David S, Johnson, Ryan D, Baskin, Alexandra M

“…Based on the postulate that glioblastoma (GBM) tumors generate anti-inflammatory prostaglandins and bile salts to gain immune privilege, we analyzed 712 tumors…”
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Hijacking Sexual Immuno-Privilege in GBM-An Immuno-Evasion Strategy by Sharpe, Martyn A, Baskin, David S, Jenson, Amanda V, Baskin, Alexandra M

“…Regulatory T-cells (Tregs) are immunosuppressive T-cells, which arrest immune responses to 'Self' tissues. Some immunosuppressive Tregs that recognize seminal…”
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Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells by Sharpe, Martyn A., Baskin, David S., Pichumani, Kumar, Ijare, Omkar B., Helekar, Santosh A.

“…Electromagnetic fields (EMF) raise intracellular levels of reactive oxygen species (ROS) that can be toxic to cancer cells. Because weak magnetic fields…”
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Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3 by Sharpe, Martyn A, Baskin, David S

“…Monoamine oxidases A and B (MAOA and MAOB) are highly expressed in many cancers. Here we investigated the level of MAOB in gliomas and confirmed its high…”
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Advances in gene therapy for high-grade glioma: a review of the clinical evidence by Goldman, Matthew J, Baskin, Alexandra M, Sharpe, Martyn A, Baskin, David S

“…High-grade glioma (HGG) is one of the most deadly and difficult cancers to treat. Despite intense research efforts, there has not been a significant…”
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Case Report: End-Stage Recurrent Glioblastoma Treated With a New Noninvasive Non-Contact Oncomagnetic Device by Baskin, David S., Sharpe, Martyn A., Nguyen, Lisa, Helekar, Santosh A.

“…Alternating electric field therapy has been approved for glioblastoma (GBM). We have preclinical evidence for anticancer effects in GBM cell cultures and mouse…”
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Glioblastoma Presenting with Pure Alexia and Palinopsia Involving the Left Inferior Occipital Gyrus and Visual Word Form Area Evaluated with Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Tractography by Huang, Meng, Baskin, David S, Fung, Steve

“…Background Rapid word recognition and reading fluency is a specialized cortical process governed by the visual word form area (VWFA), which is localized to the…”
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Fractionated Stereotactic Radiotherapy for Pituitary Adenomas: Single-Center Experience in 75 Consecutive Patients by Barber, Sean M, Teh, Bin S, Baskin, David S

“…BACKGROUND:Early results of postoperative fractionated stereotactic radiotherapy (FSRT) for functional and nonfunctional pituitary adenomas appear promising,…”
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Retinal Hemifield Slide Phenomenon as a Presenting Symptom of Pituitary Abscess 2 Months After Pituitary Adenoma Resection by Schwartz, Lindsey, Raviskanthan, Subahari, Mortensen, Peter W., Baskin, David S., Lee, Andrew G.

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Ex Vivo 1H NMR study of pituitary adenomas to differentiate various immunohistochemical subtypes by Ijare, Omkar B., Baskin, David S., Pichumani, Kumar

“…Pituitary adenomas (PAs) are benign growths arising from epithelial cells in the adenohypophysis of the pituitary gland. To date, there has been no detailed…”
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Superior Petrosal Vein Sacrifice During Microvascular Decompression: Perioperative Complication Rates and Comparison with Venous Preservation by Liebelt, Brandon D., Barber, Sean M., Desai, Viren R., Harper, Richard, Zhang, Jonathan, Parrish, Rob, Baskin, David S., Trask, Todd, Britz, Gavin W.

“…To investigate potential effect of sacrifice of the superior petrosal vein (SPV) on postoperative complications after microvascular decompression (MVD)…”
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A "Clickable" Probe for Active MGMT in Glioblastoma Demonstrates Two Discrete Populations of MGMT by Raghavan, Sudhir, Baskin, David S, Sharpe, Martyn A

“…Various pathways can repair DNA alkylation by chemotherapeutic agents such as temozolomide (TMZ). The enzyme O -methylguanine methyltransferase (MGMT) removes…”
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Method for noninvasive whole-body stimulation with spinning oscillating magnetic fields and its safety in mice by Hambarde, Shashank, Nguyen, Lisa, Manalo, Jeanne, John, Blessy, Baskin, David S., Helekar, Santosh A.

“…We recently reported shrinkage of untreatable recurrent glioblastoma (GBM) in an end-stage patient using noninvasive brain stimulation with a spinning…”
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Selective induction of rapid cytotoxic effect in glioblastoma cells by oscillating magnetic fields by Helekar, Santosh A., Hambarde, Shashank, Ijare, Omkar B., Pichumani, Kumar, Baskin, David S., Sharpe, Martyn A.

“…Purpose The mechanisms underlying anticancer effects of electromagnetic fields are poorly understood. An alternating electric field-generating therapeutic…”
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