Search Results - "Basketter, D A"

Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects by Peiser, M, Tralau, T, Heidler, J, Api, A M, Arts, J H; E, Basketter, D A, English, J, Diepgen, T L, Fuhlbrigge, R C, Gaspari, A A, Johansen, J D, Karlberg, A T, Kimber, I, Lepoittevin, J P, Liebsch, M, Maibach, H I, Martin, S F, Merk, H F, Platzek, T, Rustemeyer, T, Schnuch, A, Vandebriel, R J, White, I R, Luch, A

“…Contact allergies are complex diseases, and one of the important challenges for public health and immunology. The German 'Federal Institute for Risk…”
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T helper cell 2 immune skewing in pregnancy/early life: chemical exposure and the development of atopic disease and allergy by McFadden, J.P., Thyssen, J.P., Basketter, D.A., Puangpet, P., Kimber, I.

“…Summary During the last 50 years there has been a significant increase in Western societies of atopic disease and associated allergy. The balance between…”
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Why does allergic contact dermatitis exist? by McFadden, J.P., Puangpet, P., Basketter, D.A., Dearman, R.J., Kimber, I.

“…Summary The skin immune system’s propensity to produce allergic contact dermatitis (ACD) to harmless chemicals, while otherwise being an efficient defence…”
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Skin sensitization: strategies for the assessment and management of risk by Basketter, D.A.

“…Summary Allergic contact dermatitis (ACD) is to a considerable extent a preventable disease. Limitation can be achieved by correct identification of skin…”
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Inter-relationships between different classes of chemical allergens by Dearman, R. J., Basketter, D. A., Kimber, I

“…ABSTRACT Although allergic sensitization of the respiratory tract induced by chemicals is not as common as skin sensitization, it is nevertheless an important…”
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The Hapten-Atopy hypothesis II: the 'cutaneous hapten paradox' by McFadden, J. P., Dearman, R. J., White, J. M. L., Basketter, D. A., Kimber, I.

“…Cite this as: J. P. McFadden, R. J. Dearman, J. M. L. White, D. A. Basketter and I. Kimber, Clinical & Experimental Allergy, 2011 (41) 327–337. Summary One…”
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The local lymph node assay: past, present and future by Kimber, Ian, Dearman, R. J., Basketter, D. A., Ryan, C. A., Gerberick, G. F.

“…The local lymph node assay (LLNA) was developed originally as a method for the identification of chemicals that have the potential to cause skin sensitization…”
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The hapten-atopy hypothesis III: the potential role of airborne chemicals by McFadden, J.P., Basketter, D.A., Dearman, R.J., Puangpet, P., Kimber, I.

“…Summary One explanation for the large increase in the prevalence of atopic disease in developed countries during the last 50 years is the ‘hygiene hypothesis’…”
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Fragrance chemicals in domestic and occupational products by Rastogi, S. C., Heydorn, S., Johansen, J. D., Basketter, D. A.

“…Epidemiological studies have described an increasing prevalence of fragrance allergy and indicated an association with hand eczema. 59 domestic and…”
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Skin sensitization: Implications for integration of clinical data into hazard identification and risk assessment by Basketter, D A, White, I R, McFadden, J P, Kimber, I

“…Skin sensitization associated with allergic contact dermatitis is a common health problem and is an important consideration for toxicologists in safety…”
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Non-animal approaches in skin toxicology by Basketter, D. A.

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Ranking of hair dye substances according to predicted sensitization potency: quantitative structure-activity relationships by Søsted, H., Basketter, D. A., Estrada, E., Johansen, J. D., Patlewicz, G. Y.

“…Allergic contact dermatitis following the use of hair dyes is well known. Many chemicals are used in hair dyes and it is unlikely that all cases of hair dye…”
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A general population from Thailand: incidence of common allergens with emphasis on para-phenylenediamine by White, J. M. L., Gilmour, N. J., Jeffries, D., Duangdeeden, I., Kullavanijaya, P., Basketter, D. A., McFadden, J. P.

“…Summary Background Most studies on the prevalence of allergy to the permanent hair dye chemical para‐phenylenediamine (PPD) are reported from populations of…”
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Local lymph node assay — validation, conduct and use in practice by Basketter, D.A., Evans, P., Fielder, R.J., Gerberick, G.F., Dearman, R.J., Kimber, I.

“…The validation of alternative methods is a relatively new activity in toxicology. The local lymph node assay (LLNA), a novel method for the identification of…”
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Defining occupational and consumer exposure limits for enzyme protein respiratory allergens under REACH by Basketter, D.A, Broekhuizen, C, Fieldsend, M, Kirkwood, S, Mascarenhas, R, Maurer, K, Pedersen, C, Rodriguez, C, Schiff, H.-E

“…Abstract A wide range of substances have been recognized as sensitizing, either to the skin and/or to the respiratory tract. Many of these are useful…”
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p-Phenylenediamine allergy: the role of Bandrowski's base by White, J. M. L., Kullavanijaya, P., Duangdeeden, I., Zazzeroni, R., Gilmour, N. J., Basketter, D. A., McFadden, J. P.

“…Summary p‐Phenylenediamine (PPD) is a commonly used hair‐dye and a potent skin allergen. The mechanism of sensitization is unknown, as PPD is protein…”
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Irritant dermatitis, irritancy and its role in allergic contact dermatitis by Smith, H. R., Basketter, D. A., McFadden, J. P.

“…Summary Irritant contact dermatitis is the clinical result of sufficient inflammation arising from release of pro‐inflammatory cytokines from skin cells…”
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Analysis of para-phenylenediamine allergic patients in relation to strength of patch test reaction by Ho, S.G.Y., Basketter, D.A., Jefferies, D., Rycroft, R.J.G., White, I.R., Mcfadden, J.P.

“…Summary Background  Despite having a positive patch test reaction to para‐phenylenediamine (PPD), some patients continue to dye their hair, while others are…”
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Use of the local lymph node assay for the estimation of relative contact allergenic potency by Basketter, D. A., Blaikie, L., Dearman, R. J., Kimber, I., Ryan, C. A., Gerberick, G. F., Harvey, P., Evans, P., White, I. R., Rycroft, R. J. G.

“…The effective toxicological evaluation of skin sensitization demands that potential contact allergens are identified and that the likely risks of sensitization…”
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Classification of contact allergens according to potency: proposals by Kimber, I, Basketter, D.A, Butler, M, Gamer, A, Garrigue, J.-L, Gerberick, G.F, Newsome, C, Steiling, W, Vohr, H.-W

“…It is clear that contact allergens vary substantially with regard to the relative potency with which they are able to induce skin sensitisation. Considerations…”
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