Search Results - "Baskcomb, Linda"

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair by Polo, Sophie E., Blackford, Andrew N., Chapman, J. Ross, Baskcomb, Linda, Gravel, Serge, Rusch, Andre, Thomas, Anoushka, Blundred, Rachel, Smith, Philippa, Kzhyshkowska, Julia, Dobner, Thomas, Taylor, A. Malcolm R., Turnell, Andrew S., Stewart, Grant S., Grand, Roger J., Jackson, Stephen P.

“…DNA double-strand break (DSB) signaling and repair are critical for cell viability, and rely on highly coordinated pathways whose molecular organization is…”
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Stratification of Wilms tumor by genetic and epigenetic analysis by Scott, Richard H, Murray, Anne, Baskcomb, Linda, Turnbull, Clare, Loveday, Chey, Al-Saadi, Reem, Williams, Richard, Breatnach, Fin, Gerrard, Mary, Hale, Juliet, Kohler, Janice, Lapunzina, Pablo, Levitt, Gill A, Picton, Sue, Pizer, Barry, Ronghe, Milind D, Traunecker, Heidi, Williams, Denise, Kelsey, Anna, Vujanic, Gordan M, Sebire, Neil J, Grundy, Paul, Stiller, Charles A, Pritchard-Jones, Kathy, Douglas, Jenny, Rahman, Nazneen

“…Somatic defects at five loci, WT1, CTNNB1, WTX, TP53 and the imprinted 11p15 region, are implicated in Wilms tumor, the commonest childhood kidney cancer. In…”
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Constitutional 11p15 abnormalities, including heritable imprinting center mutations, cause nonsyndromic Wilms tumor by Douglas, Jenny, Maher, Eamonn R, Cook, Jackie A, Barker, Karen, Craft, Alan, Baskcomb, Linda, Gerrard, Mary, Rahman, Nazneen, Scott, Richard H, Levitt, Gill A, Hanks, Sandra, Picton, Sue, Huxter, Nikki, Williams, Denise, Stiller, Charles A, Pritchard-Jones, Kathy, Kohler, Janice A, Ronghe, Milind D, Pizer, Barry, Pujol, Pascal, Birch, Jillian M

“…Constitutional abnormalities at the imprinted 11p15 growth regulatory region cause syndromes characterized by disordered growth, some of which include a risk…”
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PHOX2B analysis in non-syndromic neuroblastoma cases shows novel mutations and genotype-phenotype associations by McConville, Carmel, Reid, Sarah, Baskcomb, Linda, Douglas, Jenny, Rahman, Nazneen

“…Neuroblastoma (NB) is an embryonal tumor originating from neural crest cells and is one of the most common solid tumors of childhood. Recently, constitutional…”
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Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4 by Polo, Sophie E, Kaidi, Abderrahmane, Baskcomb, Linda, Galanty, Yaron, Jackson, Stephen P

“…The chromatin remodelling factor chromodomain helicase DNA‐binding protein 4 (CHD4) is a catalytic subunit of the NuRD transcriptional repressor complex. Here,…”
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Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response by Beli, Petra, Lukashchuk, Natalia, Wagner, Sebastian A., Weinert, Brian T., Olsen, Jesper V., Baskcomb, Linda, Mann, Matthias, Jackson, Stephen P., Choudhary, Chunaram

“…The regulatory networks of the DNA damage response (DDR) encompass many proteins and posttranslational modifications. Here, we use mass spectrometry-based…”
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A genome wide linkage search for breast cancer susceptibility genes by Smith, Paula, McGuffog, Lesley, Easton, Douglas F., Mann, Graham J., Pupo, Gulietta M., Newman, Beth, Chenevix-Trench, Georgia, Szabo, Csilla, Southey, Melissa, Renard, Hélène, Odefrey, Fabrice, Lynch, Henry, Stoppa-Lyonnet, Dominique, Couch, Fergus, Hopper, John L., Giles, Graham G., McCredie, Margaret R. E., Buys, Saundra, Andrulis, Irene, Senie, Ruby, Goldgar, David E., Oldenburg, Rogier, Kroeze-Jansema, Karin, Kraan, Jaennelle, Meijers-Heijboer, Hanne, Klijn, Jan G. M., van Asperen, Christi, van Leeuwen, Inge, Vasen, Hans F. A., Cornelisse, Cees J., Devilee, Peter, Baskcomb, Linda, Seal, Sheila, Barfoot, Rita, Mangion, Jon, Hall, Anita, Edkins, Sarah, Rapley, Elizabeth, Wooster, Richard, Chang-Claude, Jenny, Eccles, Diana, Evans, D. Gareth, Futreal, P. Andrew, Nathanson, Katherine L., Weber, Barbara L., Rahman, Nazneen, Stratton, Michael R.

“…Mutations in known breast cancer susceptibility genes account for a minority of the familial aggregation of the disease. To search for further breast cancer…”
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Evaluation of RAD50 in familial breast cancer predisposition by Tommiska, Johanna, Seal, Sheila, Renwick, Anthony, Barfoot, Rita, Baskcomb, Linda, Jayatilake, Hiran, Bartkova, Jirina, Tallila, Jonna, Kaare, Milja, Tamminen, Anitta, Heikkilä, Päivi, Evans, D. Gareth, Eccles, Diana, Aittomäki, Kristiina, Blomqvist, Carl, Bartek, Jiri, Stratton, Michael R., Nevanlinna, Heli, Rahman, Nazneen

“…The genes predisposing to familial breast cancer are largely unknown, but 5 of the 6 known genes are involved in DNA damage repair. RAD50 is part of a highly…”
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