Search Results - "Baska, Rose Ann"

Discovery of N-Isoxazolyl Biphenylsulfonamides as Potent Dual Angiotensin II and Endothelin A Receptor Antagonists by Murugesan, Natesan, Tellew, John E, Gu, Zhengxiang, Kunst, Bridgette L, Fadnis, Leena, Cornelius, Lyndon A, Baska, Rose Ann F, Yang, Yifan, Beyer, Sophie M, Monshizadegan, Hossain, Dickinson, Kenneth E, Panchal, Balkrushna, Valentine, Maria T, Chong, Saeho, Morrison, Richard A, Carlson, Kenneth E, Powell, James R, Moreland, Suzanne, Barrish, Joel C, Kowala, Mark C, Macor, John E

“…The ETA receptor antagonist (2) (N-(3,4-dimethyl-5-isoxazolyl)-4‘-(2-oxazolyl)-[1,1‘-biphenyl]-2-sulfonamide, BMS-193884) shares the same biphenyl core as a…”
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Discovery of 4′-[(Imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/Angiotensin II receptor antagonists by Tellew, John E, Baska, Rose Ann F, Beyer, Sophie M, Carlson, Kenneth E, Cornelius, Lyndon A, Fadnis, Leena, Gu, Zhengxiang, Kunst, Bridgette L, Kowala, Mark C, Monshizadegan, Hossain, Murugesan, Natesan, Ryan, Carol S, Valentine, Maria T, Yang, Yifan, Macor, John E

“…A series of 4′-[(imidazol-1-yl)methyl]biphenylsulfonamides has potent antagonist activity against both angiotensin II AT 1 and endothelin ET A receptors. Such…”
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Dual Angiotensin II and Endothelin A Receptor Antagonists:  Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics by Murugesan, Natesan, Gu, Zhengxiang, Fadnis, Leena, Tellew, John E, Baska, Rose Ann F, Yang, Yifan, Beyer, Sophie M, Monshizadegan, Hossain, Dickinson, Kenneth E, Valentine, Maria T, Humphreys, W. Griffith, Lan, Shih-Jung, Ewing, William R, Carlson, Kenneth E, Kowala, Mark C, Zahler, Robert, Macor, John E

“…In a previous report we demonstrated that merging together key structural elements present in an AT1 receptor antagonist (1, irbesartan) with key structural…”
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Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension by Kowala, Mark C, Murugesan, Natesan, Tellew, John, Carlson, Kenneth, Monshizadegan, Hossain, Ryan, Carol, Gu, Zhengxiang, Kane, Bridgette, Fadnis, Leena, Baska, Rose Ann, Beyer, Sophie, Arthur, Susan, Dickinson, Kenneth, Zhang, Donglu, Perrone, Mark, Ferrer, Pam, Giancarli, Mary, Baumann, Jergen, Bird, Eileen, Panchal, Balkrushna, Yang, Yifan, Trippodo, Nick, Barrish, Joel, Macor, John E

“…Angiotensin II and endothelin-1 activate their respective AT(1) and ET(A) receptors on vascular smooth muscle cells, producing vasoconstriction, and both…”
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Identification of [ 3H]P1075 binding sites and P1075-activated K + currents in ovine choroid plexus cells by Dickinson, Kenneth E.J, Baska, Rose Ann, Cohen, Robert B, Bryson, Catherine C, Smith, Mark A, Schroeder, Kirk, Lodge, Nicholas J

“…This study examined the pharmacological characteristics of binding sites for the potent K + channel opener [ 3H]P1075, as well as the functional effects of…”
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