Search Results - "Basinger, M A"

Association between increased atrial natriuretic peptide and reduced cisplatin nephrotoxicity in rats by Ormond, P M, Basinger, M A, Jones, M M, Hande, K R

“…Plasma atrial natriuretic peptide (ANP) concentrations were monitored in two experimental models of protection from cisplatin nephrotoxicity. Sprague-Dawley…”
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L-methionine antagonism of cis-platinum nephrotoxicity by Basinger, M A, Jones, M M, Holscher, M A

“…L-Methionine administered simultaneously with cis-platinum (CDDP) iv results in a significant reduction of the nephrotoxicity normally associated with CDDP…”
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Thiol and thioether suppression of cis-platinum-induced nephrotoxicity in rats bearing the Walker 256 carcinosarcoma by Jones, M M, Basinger, M A

“…An examination of eighteen thiols and thio ethers revealed that the simultaneous administration of several of these with cis-platinum (CDDP) at 7.5 mg/kg (25…”
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Coadministration of dimethyl sulfoxide reduces cisplatin nephrotoxicity by Jones, M M, Basinger, M A, Field, L, Holscher, M A

“…The administration of dimethyl sulfoxide with cisplatin at a mole ratio of 200:1 results in a considerable reduction in the nephrotoxicity produced when…”
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Effect of chelate treatments on kidney, bone and brain lead levels of lead-intoxicated mice by Jones, M M, Basinger, M A, Gale, G R, Atkins, L M, Smith, A B, Stone, A

“…The effects of chelating agent treatment with meso-2,3-dimercaptosuccinic acid (DMSA), Na2CaEDTA, Na2ZnEDTA, and Na3ZnDTPA on the organ lead levels of…”
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Mobilization of lead in mice by administration of monoalkyl esters of meso-2,3-dimercaptosuccinic acid by Walker, Jr, E M, Stone, A, Milligan, L B, Gale, G R, Atkins, L M, Smith, A B, Jones, M M, Singh, P K, Basinger, M A

“…The following six monoalkyl esters of meso-2,3-dimercaptosuccinic acid (DMSA) were synthesized and evaluated for relative activities in mobilizing lead from…”
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Enhancement of iron excretion via monoanionic 3-hydroxypyrid-4-ones by Molenda, John Josef, Jones, Mark M, Basinger, Mark A

“…The ability of 3-hydroxypyrid-4-ones bearing either a carboxylic acid or sulfonic acid group to mobilize iron into the bile and urine of normal rats has been…”
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Relative effectiveness of some compounds for the control of cisplatin-induced nephrotoxicity by Jones, M M, Basinger, M A, Holscher, M A

“…Several procedures which have been reported as effective for the control of cisplatin induced nephrotoxicity were compared in the Sprague-Dawley rat using the…”
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Prevention of cisplatin nephrotoxicity by exogenous atrial natriuretic peptide by Deegan, Patricia M., Basinger, Mark A., Jones, Mark M., Hande, Kenneth R.

“…The ability of atrial natriuretic peptide (ANP) to prevent cisplatin-induced nephrotoxicity was compared to the protective effect of 3% NaCl. ANP (1 μ/kg/min),…”
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Thioether suppression of cisplatin nephrotoxicity in the rat by Jones, M M, Basinger, M A, Holscher, M A

“…Six compounds containing a thioether group were examined as agents for the reduction of the nephrotoxicity caused by cisplatin (CDDP) in the rat. Of these,…”
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A comparative study of the influence of vicinal dithiols and a dithiocarbamate on the biliary excretion of cadmium in rat by Jones, M M, Cherian, M G, Singh, P K, Basinger, M A, Jones, S G

“…The effect of two vicinal dithiols, 2,3-dimercaptopropan-1-ol (BAL) and N-(2,3-dimercaptopropyl)phthalamidic acid (DMPA), and a dithiocarbamate, sodium…”
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The role of the renin-angiotensin system in cisplatin nephrotoxicity by Deegan, P M, Nolan, C, Ryan, M P, Basinger, M A, Jones, M M, Hande, K R

“…The role of the renin-angiotensin system (RAS) in the pathogenesis of cisplatin nephrotoxicity was evaluated in an experimental rat model using a specific,…”
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The relative nephrotoxicity of cisplatin, cis-[Pt(NH3)2(guanosine)2]2+, and the hydrolysis product of cisplatin in the rat by JONES, M. M, BASINGER, M. A, BEATY, J. A, HOLSCHER, M. A

“…An examination of the comparative nephrotoxicity in the rat of cisplatin, its hydrolysis product (mostly cis-[Pt(NH3)2Cl(H2O)]+ under the conditions applied),…”
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Design of in vivo Cadmium-Mobilizing Agents: Synthesis and Properties of Monobenzyl meso-2,3-Dimercaptosuccinate by Jones, Mark M, Singh, Pramod K, Basinger, Mark A, Gale, Glen R, Smith, Alayne B, Harris, Wesley R

“…A novel method for the synthesis of monoesters of meso-2,3-dimercaptosuccinic acid (DMSA) is presented which utilizes the reaction of the vicinal…”
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Control of nephrotoxicity in the rat during repeated cis-platinum treatments by Jones, M M, Basinger, M A

“…The nephrotoxicity of cis-platinum (CDDP) in the rat can be controlled throughout a series of weekly administrations of CDDP (each of 5 mg kg-1, i.v.) for at…”
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Antidotes for gold (sodium bis[thiosulfato]gold[I]) intoxication in mice by Basinger, M A, Gibbs, S J, Forti, R L, Mitchell, W M, Jones, M M

“…Eight compounds were examined to determine their relative efficacy as antidotes in acute gold intoxication in mice after the intraperitoneal injection of 200…”
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Dependence on chelating agent properties of nephrotoxicity and testicular damage in male mice during cadmium decorporation by Jones, S G, Holscher, M A, Basinger, M A, Jones, M M

“…An examination of the histopathological appearance of the kidneys of mice treated with cadmium chloride (s.c.) and simultaneously given 1 of 3 chelating agents…”
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N-benzyl-N-lactyl dithiocarbamate treatment of mice after chronic cadmium administration by GALE, G. R, WALKER, E. M, SMITH, A. B, JONES, M. M, STONE, A, BASINGER, M. A, SINGH, P. K

“…Administration of N-benzyl-N-lactyl dithiocarbamate (BLDTC) to mice after chronic cadmium (Cd) administration evoked a prompt, dose-dependent reduction of the…”
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Meso-2,3-dimercaptosuccinic acid and sodium N-benzyl-N-dithiocarboxy-D-glucamine as antagonists for cadmium intoxication by JONES, M. M, BASINGER, M. A, TOPPING, R. J, GALE, G. R, JONES, S. G, HOLSCHER, M. A

“…Orally administered meso-2,3-dimercaptosuccinic acid (DMSA) is an effective antagonist for acute oral cadmium chloride (1 mmol/kg) intoxication in mice when…”
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Antagonists for acute oral cadmium chloride intoxication by Basinger, M A, Jones, M M, Holscher, M A, Vaughn, W K

“…An examination has been carried out on the relative efficacy of a number of chelating agents when acting as antagonists for oral cadmium chloride intoxication…”
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