Search Results - "Basile, Vittoria"
-
1
Oligometastatic adrenocortical carcinoma: the role of image-guided thermal ablation
Published in European radiology (01-12-2020)“…Objectives To evaluate the impact of image-guided ablation of liver and lung metastases from adrenocortical carcinoma (ACC). Methods Patients with…”
Get full text
Journal Article -
2
Sex Differences on Mitotane Concentration and Treatment Outcome in Patients with Adrenocortical Carcinoma
Published in Life (Basel, Switzerland) (23-03-2021)“…(1) Background: In clinical settings, data regarding sex are rarely investigated. In women, factors such as body size and composition, hormonal variations,…”
Get full text
Journal Article -
3
Sex-Based Evaluation of Lipid Profile in Postoperative Adjuvant Mitotane Treatment for Adrenocortical Carcinoma
Published in Biomedicines (03-08-2022)“…Background: A wide interindividual variability in mitotane concentrations and treatment-related dyslipidemia have been reported. Here, we aimed to underline…”
Get full text
Journal Article -
4
Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma
Published in Cells (Basel, Switzerland) (04-04-2020)“…Adrenocortical carcinoma (ACC) is a rare cancer with poor prognosis. Mitotane, the standard treatment for ACC, impairs adrenocortical steroid biosynthesis and…”
Get full text
Journal Article -
5
Sorveglianza vs terapia adiuvante del carcinoma corticosurrenalico: nuovi fattori prognostici
Published in L'Endocrinologo (2023)Get full text
Journal Article -
6
La strategia nell’uso del mitotane
Published in L'Endocrinologo (2020)Get full text
Journal Article -
7
Pregnancy in patients with adrenocortical carcinoma: a case-based discussion
Published in Reviews in endocrine & metabolic disorders (01-02-2023)“…Although adrenocortical carcinoma (ACC) during pregnancy is rare, a retrospective review of a case series at our hospital revealed that almost one third of our…”
Get full text
Journal Article -
8
Lung ultrasound for the early diagnosis of COVID-19 pneumonia: an international multicenter study
Published in Intensive care medicine (01-04-2021)“…Purpose To analyze the application of a lung ultrasound (LUS)-based diagnostic approach to patients suspected of COVID-19, combining the LUS likelihood of…”
Get full text
Journal Article -
9
Decision-making for adrenocortical carcinoma: surgical, systemic, and endocrine management options
Published in Expert review of anticancer therapy (02-11-2018)“…Introduction: Adrenocortical carcinoma (ACC) is a rare tumor characterized by poor prognosis in most cases. Moreover, in most cases ACC produces an excess of…”
Get full text
Journal Article -
10
Cardiometabolic Disease Burden and Steroid Excretion in Benign Adrenal Tumors : A Cross-Sectional Multicenter Study
Published in Annals of internal medicine (01-03-2022)“…Benign adrenal tumors are commonly discovered on cross-sectional imaging. Mild autonomous cortisol secretion (MACS) is regularly diagnosed, but its effect on…”
Get full text
Journal Article -
11
Unwanted Hormonal and Metabolic Effects of Postoperative Adjuvant Mitotane Treatment for Adrenocortical Cancer
Published in Cancers (14-09-2020)“…Mitotane is widely used for the treatment of adrenocortical cancer (ACC), although the drug-related toxicity complicates its use. The aim of this study is to…”
Get full text
Journal Article -
12
The management of postoperative disease recurrence in patients with adrenocortical carcinoma: a retrospective study in 106 patients
Published in European journal of endocrinology (10-01-2023)“…The management of adrenocortical carcinoma (ACC) recurrences remains controversial, and we present herein our experience with postoperative ACC recurrences…”
Get full text
Journal Article -
13
Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study
Published in The lancet. Diabetes & endocrinology (01-09-2020)“…Cross-sectional imaging regularly results in incidental discovery of adrenal tumours, requiring exclusion of adrenocortical carcinoma (ACC). However,…”
Get full text
Journal Article -
14
Germline NGS targeted analysis in adult patients with sporadic adrenocortical carcinoma
Published in European journal of cancer (1990) (01-07-2024)“…Adrenocortical carcinoma (ACC) is a rare cancer that arises sporadically or due to hereditary syndromes. Data on germline variants (GVs) in sporadic ACC are…”
Get full text
Journal Article -
15
-
16
New Findings on Presentation and Outcome of Patients With Adrenocortical Cancer: Results From a National Cohort Study
Published in The journal of clinical endocrinology and metabolism (18-09-2023)“…Abstract Context Because of the rarity of adrenocortical cancer (ACC), only a few population-based studies are available, and they reported limited details in…”
Get full text
Journal Article -
17
Activity and safety of temozolomide in advanced adrenocortical carcinoma patients
Published in European journal of endocrinology (01-12-2019)“…Objective Temozolomide has shown a significant anti-proliferative activity on adrenocortical cancer (ACC) cells in vitro. Design On the basis of these results…”
Get full text
Journal Article -
18
Adjuvant mitotane therapy is beneficial in non-metastatic adrenocortical carcinoma at high risk of recurrence
Published in European journal of endocrinology (01-06-2019)“…Objective Many patients with adrenocortical carcinoma (ACC) suffer from tumor recurrence despite radical surgery. Evidence on the post-operative use of…”
Get full text
Journal Article -
19
Adjuvant mitotane versus surveillance in low-grade, localised adrenocortical carcinoma (ADIUVO): an international, multicentre, open-label, randomised, phase 3 trial and observational study
Published in The lancet. Diabetes & endocrinology (01-10-2023)“…Adjuvant treatment with mitotane is commonly used after resection of adrenocortical carcinoma; however, treatment remains controversial, particularly if risk…”
Get full text
Journal Article -
20
Effects of mitotane on the hypothalamic–pituitary–adrenal axis in patients with adrenocortical carcinoma
Published in European journal of endocrinology (01-10-2017)“…Objective Mitotane, a drug used to treat adrenocortical cancer (ACC), inhibits multiple enzymatic steps of adrenocortical steroid biosynthesis, potentially…”
Get full text
Journal Article