Search Results - "Bashenko, Yulia"
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A molecular signature in blood identifies early Parkinson's disease
Published in Molecular neurodegeneration (31-05-2012)“…The search for biomarkers in Parkinson's disease (PD) is crucial to identify the disease early and monitor the effectiveness of neuroprotective therapies. We…”
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2
Processing and activation of latent heparanase occurs in lysosomes
Published in Journal of cell science (01-05-2004)“…Heparanase is a heparan sulfate degrading endoglycosidase participating in extracellular matrix degradation and remodeling. Heparanase is synthesized as a 65…”
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3
Heparanase Uptake Is Mediated by Cell Membrane Heparan Sulfate Proteoglycans
Published in The Journal of biological chemistry (15-10-2004)“…Heparanase is a mammalian endoglycosidase that degrades heparan sulfate (HS) at specific intrachain sites, an activity that is strongly implicated in cell…”
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4
High-dose acetaminophen inhibits the lethal effect of doxorubicin in HepG2 cells: the role of P-glycoprotein and mitogen-activated protein kinase p44/42 pathway
Published in The Journal of pharmacology and experimental therapeutics (01-09-2007)“…Doxorubicin (DOX) is a widely used chemotherapeutic drug for human hepatocellular carcinoma (HCC). A major limitation to its effectiveness is the development…”
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5
Transforming growth factor-alpha stimulates enterocyte proliferation and accelerates intestinal recovery following methotrexate-induced intestinal mucositis in a rat and a cell culture model
Published in Pediatric surgery international (01-12-2008)“…Purpose Recent evidence suggests that transforming growth factor-alpha (TGF-α) enhances enterocyte proliferation and exerts a gut trophic effect. The purpose…”
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Dietary palmitic acid modulates intestinal re-growth after massive small bowel resection in a rat
Published in Pediatric surgery international (01-12-2008)“…Purpose Among factors promoting intestinal adaptation after bowel resection, dietary fatty acids have a special role. The purpose of the present study was to…”
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Crystalloid or colloid resuscitation of uncontrolled hemorrhagic shock after moderate splenic injury
Published in Shock (Augusta, Ga.) (01-03-2000)“…Using a standardized moderate splenic injury (MSI) model of uncontrolled hemorrhagic shock, we studied the effect of vigorous crystalloid or colloid fluid…”
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8
Heparanase induces vascular endothelial growth factor expression : Correlation with p38 phosphorylation levels and Src activation
Published in Cancer research (Chicago, Ill.) (01-02-2006)“…Heparanase is an endo-beta-D-glucuronidase involved in cleavage of heparan sulfate moieties and hence participates in extracellular matrix (ECM) degradation…”
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Heparanase affects adhesive and tumorigenic potential of human glioma cells
Published in Cancer research (Chicago, Ill.) (15-11-2003)“…Heparanase is an endo-beta-glucuronidase responsible for the cleavage of heparan sulfate, participating in extracellular matrix degradation and remodeling…”
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Parenteral but Not Enteral Omega-3 Fatty Acids (Omegaven) Modulate Intestinal Regrowth After Massive Small Bowel Resection in Rats
Published in JPEN. Journal of parenteral and enteral nutrition (01-09-2010)“…Background: The purpose of the present study was to evaluate the effects of ω-3 fatty acids (Omegaven) on early intestinal adaptation in rats with short bowel…”
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11
Effect of Oral Insulin on Diabetes-Induced Intestinal Mucosal Growth in Rats
Published in Digestive diseases and sciences (01-09-2011)“…Background To evaluate the intestinal response to the induction of diabetes and to oral insulin (OI) administration in a rat. Methods Male Sprague–Dawley rats…”
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12
Involvement of the Multidrug Resistance P‐Glycoprotein in Acetaminophen‐Induced Toxicity in Hepatoma‐Derived HepG2 and Hep3B Cells
Published in Basic & clinical pharmacology & toxicology (01-09-2006)“…: Acetaminophen overdose causes severe hepatic failure. Although the mechanisms of acetaminophen hepatotoxicity have been well investigated, little is known…”
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13
Effect of simvastatin on intestinal recovery following gut ischemia–reperfusion injury in a rat
Published in Pediatric surgery international (2010)“…Background Pleiotropic (lipid lowering-independent) effects of statins are attributed to their antiinflammatory, antioxidant, and/or vascular actions…”
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14
Heparanase pretreatment attenuates endotoxin-induced acute lung injury in rats
Published in Shock (Augusta, Ga.) (01-08-2007)“…A central event of systemic inflammation and septic organ injury is infiltration of tissues with polymorphonuclear neutrophils, likely modulated by the…”
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Nutritional supplementation with transforming growth factor-beta inhibits intestinal adaptation after massive small bowel resection in a rat
Published in Pediatric surgery international (01-02-2011)“…Introduction Transforming growth factor beta (TGF-β) has been shown to affect epithelial cell differentiation and proliferation through epithelial-mesenchymal…”
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Effect of transforming growth factor-alpha on enterocyte apoptosis is correlated with EGF receptor expression along the villus-crypt axis during methotrexate-induced intestinal mucositis in a rat
Published in Apoptosis (London) (01-11-2008)“…The purpose of the present study was to evaluate the effect of transforming-growth factor-alpha (TGF-α) on enterocyte apoptosis following methotrexate (MTX)…”
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17
Crystalloid and colloid resuscitation of uncontrolled hemorrhagic shock following massive splenic injury
Published in Shock (Augusta, Ga.) (01-11-2001)“…Using a standardized massive splenic injury (MSI) model of uncontrolled hemorrhagic shock we studied the effect of vigorous crystalloid or colloid fluid…”
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18
Reduced rate of bacterial translocation and improved variables of natural killer cell and T-cell activity in rats surviving controlled hemorrhagic shock and treated with hypertonic saline
Published in Critical care medicine (01-04-2002)“…OBJECTIVE To examine the effect of hypertonic saline on bacterial translocation and the number and function of natural killer and T cells in controlled…”
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Improved survival in uncontrolled hemorrhagic shock induced by massive splenic injury in the proestrus phase of the reproductive cycle in the female rat
Published in Shock (Augusta, Ga.) (01-11-2003)“…Estrogen has a protective effect in adverse circulatory conditions such as trauma-hemorrhage and ischemia-reperfusion. In the present investigation…”
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Continuous fluid resuscitation for treatment of uncontrolled hemorrhagic shock following massive splenic injury in rats
Published in Shock (Augusta, Ga.) (01-12-2002)“…We have previously observed that bolus fluid resuscitation in uncontrolled hemorrhagic shock induced by solid organ injury leads to increased blood loss and…”
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