Search Results - "Basheer, Haneen A."

Preparation and Characterization of Patch Loaded with Clarithromycin Nanovesicles for Transdermal Drug Delivery by Zaid Alkilani, Ahlam, Musleh, Batool, Hamed, Rania, Swellmeen, Lubna, Basheer, Haneen A

“…Clarithromycin (CLR), categorized as a Biopharmaceutical Classification System class II drug, has several gastrointestinal tract side effects and an extremely…”
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Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment by Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus, Falconer, Robert A.

“…Polysialic acid (polySia) is a unique carbohydrate polymer expressed on the surface of NCAM (neuronal cell adhesion molecule) in a number of cancers where it…”
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Development and Evaluation of an Innovative Approach Using Niosomes Based Polymeric Microneedles to Deliver Dual Antioxidant Drugs by Zaid Alkilani, Ahlam, Abo-Zour, Hadeel, Basheer, Haneen A, Abu-Zour, Hana, Donnelly, Ryan F

“…Ascorbic acid (AA) and caffeine (CAFF) work to protect cells from ultraviolet (UV) radiation and slow down the photoaging process of the skin. However,…”
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Transdermal Delivery System of Doxycycline-Loaded Niosomal Gels: Toward Enhancing Doxycycline Stability by Zaid Alkilani, Ahlam, Sharaire, Zaina, Hamed, Rania, Basheer, Haneen A.

“…Doxycycline (DOX) is an antimicrobial agent that is susceptible to photosensitivity and thermal degradation. It addition, it causes gastrointestinal side…”
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Formulation and Evaluation of Niosomal Alendronate Sodium Encapsulated in Polymeric Microneedles: In Vitro Studies, Stability Study and Cytotoxicity Study by Zaid Alkilani, Ahlam, Abu-Zour, Hana, Alshishani, Anas, Abu-Huwaij, Rana, Basheer, Haneen A, Abo-Zour, Hadeel

“…The aim of this study is to design and evaluate a transdermal delivery system for alendronate sodium (ALS) loaded with nanocarrier to improve its permeability…”
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Study of the Chemotactic Response of Multicellular Spheroids in a Microfluidic Device by Ayuso, Jose M, Basheer, Haneen A, Monge, Rosa, Sánchez-Álvarez, Pablo, Doblaré, Manuel, Shnyder, Steven D, Vinader, Victoria, Afarinkia, Kamyar, Fernández, Luis J, Ochoa, Ignacio

“…We report the first application of a microfluidic device to observe chemotactic migration in multicellular spheroids. A microfluidic device was designed…”
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Novel 2‑Aminobenzothiazole Derivatives: Docking, Synthesis, and Biological Evaluation as Anticancer Agents by Salih, Omar M., Al-Sha’er, Mahmoud A., Basheer, Haneen A.

“…Sixteen novel 2-aminobenzothiazole compounds with different amines or substituted piperazine moieties were designed, synthesized, and tested using various…”
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Agarose Spot as a Comparative Method for in situ Analysis of Simultaneous Chemotactic Responses to Multiple Chemokines by Ahmed, Mohaned, Basheer, Haneen A., Ayuso, Jose M., Ahmet, Djevdet, Mazzini, Marco, Patel, Roshan, Shnyder, Steven D., Vinader, Victoria, Afarinkia, Kamyar

“…We describe a novel protocol to quantitatively and simultaneously compare the chemotactic responses of cells towards different chemokines. In this protocol,…”
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Evaluation of Jordan's citizens' awareness of the emerging Coronavirus (COVID-19) disease: A mixed analysis of the symptoms, transmission, and preventive measures by Almazari, Inas, Bdeir, Roba, Basheer, Haneen A

“…This study aimed to evaluate Jordan citizens' awareness, knowledge, and practice concerning Coronavirus-19 (COVID-19) symptoms, routes of transmission, and…”
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Prevalence and Predictive Factors of Masked Depression and Anxiety among Jordanian and Palestinian Couples: A Cross-Sectional Study by Jaber, Deema, Basheer, Haneen A, Elsalem, Lina, Dweib, Mohammad, Khadra, Maysa, Abduljabbar, Rami, Ghazwi, Rawan, Alhamad, Hamza

“…Although anxiety and depression are among the most prevalent mental disorders worldwide, they continue to gain less attention than their physical counterparts…”
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CCR7 as a therapeutic target in Cancer by Salem, Anwar, Alotaibi, Mashael, Mroueh, Rima, Basheer, Haneen A., Afarinkia, Kamyar

“…The CCR7 chemokine axis is comprised of chemokine ligand 21 (CCL21) and chemokine ligand 19 (CCL19) acting on chemokine receptor 7 (CCR7). This axis plays two…”
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Discovery of new PKN2 inhibitory chemotypes via QSAR-guided selection of docking-based pharmacophores by Al-Sha’er, Mahmoud A., Basheer, Haneen A., Taha, Mutasem O.

“…Serine/threonine-protein kinase N2 (PKN2) plays an important role in cell cycle progression, cell migration, cell adhesion and transcription activation…”
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Niosomal Delivery of Celecoxib and Metformin for Targeted Breast Cancer Treatment by Basheer, Haneen A, Alhusban, Maram A, Zaid Alkilani, Ahlam, Alshishani, Anas, Elsalem, Lina, Afarinkia, Kamyar

“…Breast cancer continues to be a prominent worldwide health concern and requires continued investigation into innovative therapeutic approaches. Here, we report…”
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Formulation and Evaluation of Azithromycin-Loaded Niosomal Gel: Optimization, In Vitro Studies, Rheological Characterization, and Cytotoxicity Study by Zaid Alkilani, Ahlam, Hamed, Rania, Abdo, Hajer, Swellmeen, Lubna, Basheer, Haneen A., Wahdan, Walaa, Abu Kwiak, Amani D.

“…Several novel, innovative approaches for improving transdermal delivery of BCS class III drugs have been proposed. Despite their great aqueous solubility, BCS…”
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Novel Sulfonamide–Triazine Hybrid Derivatives: Docking, Synthesis, and Biological Evaluation as Anticancer Agents by Alelaimat, Mahmoud A., Al-Sha’er, Mahmoud A., Basheer, Haneen A.

“…The biological benefits of trisubstituted 1,3,5-triazine derivatives include their ability to reduce inflammation and fight cancer. A unique series of…”
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Targeting GSK-3β enzyme by diazepino-quinolone derivatives by Swellmeen, Lubna, Basheer, Haneen A, Uzrail, Amal, Sallam, Haneen, Al-Hiari, Yusuf, Alkilani, Ahlam

“…Purpose: To synthesize a heterocyclic system containing quinolone and diazepine scaffolds as GSK-3β inhibitor. Methods: The diazepino-quinoline derivatives…”
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Application of small molecule FPR1 antagonists in the treatment of cancers by Ahmet, Djevdet S., Basheer, Haneen A., Salem, Anwar, Lu, Di, Aghamohammadi, Amin, Weyerhäuser, Patrick, Bordiga, Andrea, Almeniawi, Juman, Rashid, Sabah, Cooper, Patricia A., Shnyder, Steven D., Vinader, Victoria, Afarinkia, Kamyar

“…The formylpeptide receptor-1 (FPR1) is a member of the chemotactic GPCR-7TM formyl peptide receptor family, whose principle function is in trafficking of…”
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Hypoxia modulates CCR7 expression in head and neck cancers by Basheer, Haneen A., Pakanavicius, Edvinas, Cooper, Patricia A., Shnyder, Steven D., Martin, Lisette, Hunter, Keith D., Vinader, Victoria, Afarinkia, Kamyar

“…•Under hypoxia, the expression of CCR7 is elevated in both in vitro and in vivo models.•There is a correlation between HIF-1α and CCR7 in all head and neck…”
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Genetic variation in the ADIPOQ gene and serum adiponectin increase the risk of bladder cancer by Elsalem, Lina, Alfaqih, Mahmoud A., Al Bashir, Samir, Halalsheh, Omar, Basheer, Haneen A., Mhedat, Khawla, Khader, Yousef, Pors, Klaus

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Prevalence and predictive factors for infertility-related stress among infertile couples: A cross-sectional study from Jordan and the occupied Palestinian territories by Jaber, Deema J, Basheer, Haneen A, Albsoul-Younes, Abla M, Elsalem, Lina M, Hamadneh, Jehan M, Dweib, Mohammad K, Ahmedah, Hanadi T

“…To assess the level of infertility-related stress, associated socio-economic, and demographic factors among infertile couples living in Jordan and those living…”
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