Search Results - "Bashan, N."

Peripheral blood leucocyte subclasses as potential biomarkers of adipose tissue inflammation and obesity subphenotypes in humans by Pecht, T, Gutman‐Tirosh, A, Bashan, N, Rudich, A

“…While obesity is clearly accepted as a major risk factor for cardio‐metabolic morbidity, it is also apparent that some obese patients largely escape this…”
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Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity by Slutsky, N, Vatarescu, M, Haim, Y, Goldstein, N, Kirshtein, B, Harman-Boehm, I, Gepner, Y, Shai, I, Bashan, N, Blüher, M, Rudich, A

“…Background/Objectives: Adipose tissue (AT) autophagy gene expression is elevated in human obesity, correlating with increased metabolic risk, but mechanistic…”
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Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress by Bloch-Damti, A, Potashnik, R, Gual, P, Le Marchand-Brustel, Y, Tanti, J. F, Rudich, A, Bashan, N

“…Aims/hypothesis Induction of stress kinases leading to serine hyperphosphorylation of IRS1 may link oxidative stress to insulin resistance. The aim of this…”
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IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress by POTASHNIK, R, BLOCH-DAMTI, A, BASHAN, N, RUDICH, A

“…Oxidative stress was shown to selectively induce impaired metabolic response to insulin, raising the possible involvement of alterations in…”
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Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes by RUDICH, A, TIROSH, A, POTASHNIK, R, HEMI, R, KANETY, H, BASHAN, N

“…Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes. A Rudich , A Tirosh , R Potashnik , R Hemi , H Kanety and N Bashan…”
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Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes by RUDICH, A, TIROSH, A, POTASHNIK, R, KHAMAISI, M, BASHAN, N

“…Oxidative stress has been shown to impair insulin-stimulated glucose transporter 4 translocation in 3T3-L1 adipocytes. This study explores the potential of the…”
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Oxidative stress impairs nuclear proteins binding to the insulin responsive element in the GLUT4 promoter by PESSLER, D, RUDICH, A, BASHAN, N

“…Substantial evidence suggests an important role for the expression of GLUT4 in adipocytes, in the pathogenesis of insulin resistance and Type II…”
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Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes by Rudich, A, Kozlovsky, N, Potashnik, R, Bashan, N

“…Increased oxidant stress has been suggested to occur in diabetes and to contribute to the development of late diabetic complications. Whether oxidant stress…”
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Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC-ζ by BEN-ROMANO, R, RUDICH, A, TIROSH, A, POTASHNIK, R, SASAOKA, T, RIESENBERG, K, SCHLAEFFER, F, BASHAN, N

“…Chronic exposure of 3T3-L1 adipocytes to the HIV protease inhibitor nelfinavir induces insulin resistance, recapitulating key metabolic alterations of adipose…”
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Dynamic, open inquiry in biology learning by Zion, M, Slezak, M, Shapira, D, Link, E, Bashan, N, Brumer, M, Orian, T, Nussinowitz, R, Court, D, Agrest, B, Mendelovici, R, Valanides, N

“…In the new biology-learning curriculum for Israeli high schools, known as Biomind, students experience open-inquiry.'' This paper describes a qualitative…”
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Cellular mechanisms of insulin resistance, lipodystrophy and atherosclerosis induced by HIV protease inhibitors by Rudich, A., Ben-Romano, R., Etzion, S., Bashan, N.

“…Accumulating clinical evidence now links HIV protease inhibitors (HPIs) to the pathogenesis of insulin resistance, dyslipidaemia, lipodystrophy and…”
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Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats by Khamaisi, Mogher, Potashnik, Ruth, Tirosh, Amir, Demshchak, Eran, Rudich, Assaf, Trischler, Hans, Wessel, Klus, Bashan, Nava

“…Alpha lipoic acid (lipoate [LA]), a cofactor of α-ketodehydrogenase, exhibits unique antioxidant properties. Recent studies suggest a direct effect of LA on…”
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Regulation of glucose transport and GLUT1 glucose transporter expression by O2 in muscle cells in culture by Bashan, N, Burdett, E, Hundal, H S, Klip, A

“…The effect of varying cellular oxygenation on L6 muscle cell 2-deoxy-D-glucose transport, glucose utilization, lactate production, and expression of GLUT1 and…”
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Mechanisms of adaptation of glucose transporters to changes in the oxidative chain of muscle and fat cells by Bashan, N, Burdett, E, Gumà, A, Sargeant, R, Tumiati, L, Liu, Z, Klip, A

“…Cells in which glucose uptake is rate limiting respond to hypoxic insults with an increase in glucose transport activity. To understand the underlying cellular…”
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Lipoic acid prevention of neural tube defects in offspring of rats with streptozocin-induced diabetes by Wiznitzer, Arnon, Ayalon, Nir, Hershkovitz, Reli, Khamaisi, Mogher, Reece, E. Albert, Trischler, Hans, Bashan, Nava

“…Objective: Increased oxidant stress has been suggested to play a role in the pathogenesis of disturbed embryogenesis in diabetic pregnancies. The present study…”
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Association of a nonsense mutation (W1282X), the most common mutation in the Ashkenazi Jewish cystic fibrosis patients in Israel, with presentation of severe disease by Shoshani, T, Augarten, A, Gazit, E, Bashan, N, Yahav, Y, Rivlin, Y, Tal, A, Seret, H, Yaar, L, Kerem, E

“…Only about 30% of the cystic fibrosis chromosomes in the Israeli cystic fibrosis patient populations carry the major CF mutation (delta F508). Since different…”
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Proposed mechanisms for the induction of insulin resistance by oxidative stress by Bloch-Damti, Asnat, Bashan, Nava

“…In diabetes (type 1 and type 2), increased flux of free fatty acids and glucose is associated with increased mitochondrial reactive oxygen species (ROS)…”
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Regulation of glucose transporters--implications for insulin resistance states by Tirosh, A, Rudich, A, Bashan, N

“…Altered glucose homeostasis in the different diabetic states often results from a combination of insulin deficiency (absolute or relative), and impaired…”
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Expression and biochemical characterization of human immunodeficiency virus type 1 nef gene product by KAMINCHIK, J, BASHAN, N, PINCHASI, D, AMIT, B, SARVER, N, JOHNSTON, M. I, FISCHER, M, YAVIN, Z, GORECKI, M, PANET, A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Characterization of the mutations in the glucose‐6‐phosphatase gene in Israeli patients with glycogen storage disease type 1a: R83C in six Jews and a novel V166G mutation in a Muslim Arab by Parvari, R., Moses, S., Hershkovitz, E., Carmi, R., Bashan, N.

“…Summary Glycogen storage disease type 1a (GSD 1a), an autosomal recessive disease, is caused by the inactivity of glucose‐6‐phosphatase, the gene of which has…”
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