Search Results - "Basel, Matthew T."

System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance by Sebek, Jan, Shrestha, Tej B., Basel, Matthew T., Chamani, Faraz, Zeinali, Nooshin, Mali, Ivina, Payne, Macy, Timmerman, Sarah A., Faridi, Pegah, Pyle, Marla, O'Halloran, Martin, Dennedy, M. Conall, Bossmann, Stefan H., Prakash, Punit

“…Bio-effects following thermal treatments are a function of the achieved temperature profile in tissue, which can be estimated across tumor volumes with…”
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Using a flipped classroom in a veterinary systems physiology course increases student performance on basic knowledge and clinical applicability questions by Basel, Matthew T

“…Flipped classrooms are being utilized more frequently in biomedical education in order to provide more active learning opportunities to students although there…”
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Luminol-based bioluminescence imaging of mouse mammary tumors by Alshetaiwi, Hamad S., Balivada, Sivasai, Shrestha, Tej B., Pyle, Marla, Basel, Matthew T., Bossmann, Stefan H., Troyer, Deryl L.

“…[Display omitted] •Luminol can be used to track neutrophil invasion of tumors.•For the first time, we have shown Luminol can be used to image solid carcinomas…”
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Designing a Cleavable Cell Surface Protein for Cytotherapy and Drug Delivery Applications by Basel, Matthew T., Shrestha, Tej B., Pyle, Marla, Nguyen, Tuyen Duong Thanh, Aryal, Santosh, Troyer, Deryl L., Bossmann, Stefan H.

“…Many cytotherapy applications focus on delivering a therapeutic molecule or nanoparticle to a disease site. One challenging step in this delivery is releasing…”
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Lipophilic Near-Infrared Dyes for In Vivo Fluorescent Cell Tracking by Basel, Matthew T

“…Cells can be easily and noninvasively tracked in the body by labeling them with a lipophilic, near-infrared dye and using a live fluorescence imaging system to…”
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Magnetic-Fe/Fe3O4-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages by Wang, Hongwang, Shrestha, Tej B, Basel, Matthew T, Dani, Raj Kumar, Seo, Gwi-Moon, Balivada, Sivasai, Pyle, Marla M, Prock, Heidy, Koper, Olga B, Thapa, Prem S, Moore, David, Li, Ping, Chikan, Viktor, Troyer, Deryl L, Bossmann, Stefan H

“…The targeted delivery of therapeutics to the tumor site is highly desirable in cancer treatment, because it is capable of minimizing collateral damage. Herein,…”
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The Progress and Promise of RNA MedicineAn Arsenal of Targeted Treatments by Sasso, Janet M., Ambrose, Barbara J. B., Tenchov, Rumiana, Datta, Ruchira S., Basel, Matthew T., DeLong, Robert K., Zhou, Qiongqiong Angela

“…In the past decade, there has been a shift in research, clinical development, and commercial activity to exploit the many physiological roles of RNA for use in…”
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Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection by Udukala, Dinusha N, Wang, Hongwang, Wendel, Sebastian O, Malalasekera, Aruni P, Samarakoon, Thilani N, Yapa, Asanka S, Abayaweera, Gayani, Basel, Matthew T, Maynez, Pamela, Ortega, Raquel, Toledo, Yubisela, Bossmann, Leonie, Robinson, Colette, Janik, Katharine E, Koper, Olga B, Li, Ping, Motamedi, Massoud, Higgins, Daniel A, Gadbury, Gary, Zhu, Gaohong, Troyer, Deryl L, Bossmann, Stefan H

“…Proteases, including matrix metalloproteinases (MMPs), tissue serine proteases, and cathepsins (CTS) exhibit numerous functions in tumor biology. Solid tumors…”
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Direct treatment versus indirect: Thermo‐ablative and mild hyperthermia effects by Payne, Macy, Bossmann, Stefan H., Basel, Matthew T.

“…Hyperthermia is a rapidly growing field in cancer therapy and many advances have been made in understanding and applying the mechanisms of hyperthermia…”
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Preparing students to apply to and succeed in medical professional schools by Basel, Matthew T, Malreddy, Pradeep, Schultz, Bruce, Fong, Peying, Coetzee, Johann F, Rush, Bonnie R

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Protease-Sensitive, Polymer-Caged Liposomes: A Method for Making Highly Targeted Liposomes Using Triggered Release by Basel, Matthew T, Shrestha, Tej B, Troyer, Deryl L, Bossmann, Stefan H

“…Liposomes have become useful and well-known drug delivery vehicles because of their ability to entrap drugs without chemically modifying them and to deliver…”
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Using Naturally Occurring Bioluminescent Enzymes to Track Specific Cell Populations by Shrestha, Tej B, Basel, Matthew T

“…Luminol-based bioluminescence imaging allows noninvasive tracking of oxidatively active cells such as neutrophils. Luminol is given intravenously or…”
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Thermosensitive Liposomes for Gemcitabine Delivery to Pancreatic Ductal Adenocarcinoma by Aparicio-Lopez, Cesar B, Timmerman, Sarah, Lorino, Gabriella, Rogers, Tatiana, Pyle, Marla, Shrestha, Tej B, Basel, Matthew T

“…Treatment of pancreatic ductal adenocarcinoma with gemcitabine is limited by an increased desmoplasia, poor vascularization, and short plasma half-life…”
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Pulsed Magnetic Field Induced Fast Drug Release from Magneto Liposomes via Ultrasound Generation by Podaru, George, Ogden, Saralyn, Baxter, Amanda, Shrestha, Tej, Ren, Shenqiang, Thapa, Prem, Dani, Raj Kumar, Wang, Hongwang, Basel, Matthew T, Prakash, Punit, Bossmann, Stefan H, Chikan, Viktor

“…Fast drug delivery is very important to utilize drug molecules that are short-lived under physiological conditions. Techniques that can release model molecules…”
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Characterization of Nanostructured Surfaces Generated by Reconstitution of the Porin MspA from Mycobacterium smegmatis by Wörner, Michael, Lioubashevski, Oleg, Basel, Matthew T., Niebler, Sandra, Gogritchiani, Eliso, Egner, Nicole, Heinz, Christian, Hoferer, Jürgen, Cipolloni, Michela, Janik, Katharine, Katz, Evgeny, Braun, Andre M., Willner, Itamar, Niederweis, Michael, Bossmann, Stefan H.

“…Nanostructures with long‐term stability at the surface of gold electrodes are generated by reconstituting the porin MspA from Mycobacterium smegmatis into a…”
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In Vitro Measurement and Mathematical Modeling of Thermally-Induced Injury in Pancreatic Cancer Cells by Chamani, Faraz, Pyle, Marla M, Shrestha, Tej B, Sebek, Jan, Bossmann, Stefan H, Basel, Matthew T, Sheth, Rahul A, Prakash, Punit

“…Thermal therapies are under investigation as part of multi-modality strategies for the treatment of pancreatic cancer. In the present study, we determined the…”
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Developing a xenograft human tumor model in immunocompetent mice by Basel, Matthew T., Narayanan, Sanjeev, Ganta, Chanran, Shreshta, Tej B., Marquez, Alejandro, Pyle, Marla, Hill, Jennifer, Bossmann, Stefan H., Troyer, Deryl L.

“…Animal models are essential to cancer research, but current xenograft models are limited in their utility especially due to the lack of an immune system. Here…”
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Cell-delivered magnetic nanoparticles caused hyperthermia-mediated increased survival in a murine pancreatic cancer model by Basel, Matthew T, Balivada, Sivasai, Wang, Hongwang, Shrestha, Tej B, Seo, Gwi Moon, Pyle, Marla, Abayaweera, Gayani, Dani, Raj, Koper, Olga B, Tamura, Masaaki, Chikan, Viktor, Bossmann, Stefan H, Troyer, Deryl L

“…Using magnetic nanoparticles to absorb alternating magnetic field energy as a method of generating localized hyperthermia has been shown to be a potential…”
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T1-mapping characterization of two tumor types by Payne, Macy Marie, Mali, Ivina, Shrestha, Tej B., Basel, Matthew T., Timmerman, Sarah, Pyle, Marla, Sebek, Jan, Prakash, Punit, Bossmann, Stefan H.

“…T1 mapping is a quantitative method to characterize tissues with magnetic resonance imaging in a quick and efficient manner. It utilizes the relaxation rate of…”
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Rationally designed peptide nanosponges for cell-based cancer therapy by Wang, Hongwang, Yapa, Asanka S., Kariyawasam, Nilusha L., Shrestha, Tej B., Kalubowilage, Madumali, Wendel, Sebastian O., Yu, Jing, Pyle, Marla, Basel, Matthew T., Malalasekera, Aruni P., Toledo, Yubisela, Ortega, Raquel, Thapa, Prem S., Huang, Hongzhou, Sun, Susan X., Smith, Paul E., Troyer, Deryl L., Bossmann, Stefan H.

“…A novel type of supramolecular aggregate, named a “nanosponge” was synthesized through the interaction of novel supramolecular building blocks with trigonal…”
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