Search Results - "Basel, Alison"

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    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming by Bedi, Yudhishtar S., Wang, Haiqing, Thomas, Kara N., Basel, Alison, Prunier, Julien, Robert, Claude, Golding, Michael C.

    Published in Scientific reports (25-05-2022)
    “…Using a mouse model, studies by our group reveal that paternal preconception alcohol intake affects offspring fetal-placental growth, with long-lasting…”
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    Paternal alcohol exposures program intergenerational hormetic effects on offspring fetoplacental growth by Thomas, Kara N., Zimmel, Katherine N., Basel, Alison, Roach, Alexis N., Mehta, Nicole A., Thomas, Kelly R., Dotson, Luke J., Bedi, Yudhishtar S., Golding, Michael C.

    “…Hormesis refers to graded adaptive responses to harmful environmental stimuli where low-level toxicant exposures stimulate tissue growth and responsiveness…”
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    Maternal background alters the penetrance of growth phenotypes and sex‐specific placental adaptation of offspring sired by alcohol‐exposed males by Thomas, Kara N., Zimmel, Katherine N., Roach, Alexis N., Basel, Alison, Mehta, Nicole A., Bedi, Yudhishtar S., Golding, Michael C.

    Published in The FASEB journal (01-12-2021)
    “…Epigenetic mechanisms of paternal inheritance are an emerging area of interest in our efforts to understand fetal alcohol spectrum disorders. In rodent models…”
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    Preconception paternal alcohol exposure decreases IVF embryo survival and pregnancy success rates in a mouse model by Roach, Alexis N, Zimmel, Katherine N, Thomas, Kara N, Basel, Alison, Bhadsavle, Sanat S, Golding, Michael C

    Published in Molecular human reproduction (31-01-2023)
    “…Increasingly, couples struggling with fertility turn to assisted reproductive techniques, including IVF, to have children. Despite the demonstrated influence…”
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    Over a decade of field physiology reveals life-history specific strategies to drought in garter snakes ( Thamnophis legans ) by Holden, Kaitlyn G, Gangloff, Eric J, Miller, David A W, Hedrick, Ashley R, Dinsmore, Carli, Basel, Alison, Kutz, Greta, Bronikowski, Anne M

    “…Changing climates and severe weather events can affect population viability. Individuals need to buffer such negative fitness consequences through…”
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  8. 8

    Alterations in sperm RNAs persist after alcohol cessation and correlate with epididymal mitochondrial dysfunction by Roach, Alexis N., Bhadsavle, Sanat S., Higgins, Samantha L., Derrico, Destani D., Basel, Alison, Thomas, Kara N., Golding, Michael C.

    Published in Andrology (Oxford) (01-07-2024)
    “…Background Chronic preconception paternal alcohol use adversely modifies the sperm epigenome, inducing fetoplacental and craniofacial growth defects in the…”
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    Parental Alcohol Exposures Associate with Lasting Mitochondrial Dysfunction and Accelerated Aging in a Mouse Model by Basel, Alison, Bhadsavle, Sanat S, Scaturro, Katherine Z, Parkey, Grace K, Gaytan, Matthew N, Patel, Jai J, Thomas, Kara N, Golding, Michael C

    Published in Aging and disease (27-07-2024)
    “…Although detrimental changes in mitochondrial morphology and function are widely described symptoms of fetal alcohol exposure, no studies have followed these…”
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    Abstract 6458: Maternal and paternal alcohol exposures program higher incidence of hepatocellular carcinoma in offspring by Basel, Alison, Bhadsavle, Sanat S., Thomas, Kara N., Zimmel, Katherine N., Roach, Alexis N., Gaytan, Matthew, Parkey, Grace, Golding, Michael C.

    Published in Cancer research (Chicago, Ill.) (04-04-2023)
    “…Environmental exposures during development are known to influence adult health and disease. Specifically, early developmental exposures have been shown to…”
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