Search Results - "Basel, Alison"
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Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
Published in Scientific reports (25-05-2022)“…Using a mouse model, studies by our group reveal that paternal preconception alcohol intake affects offspring fetal-placental growth, with long-lasting…”
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Preconception paternal ethanol exposures induce alcohol-related craniofacial growth deficiencies in fetal offspring
Published in The Journal of clinical investigation (01-06-2023)Get full text
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Paternal alcohol exposures program intergenerational hormetic effects on offspring fetoplacental growth
Published in Frontiers in cell and developmental biology (11-08-2022)“…Hormesis refers to graded adaptive responses to harmful environmental stimuli where low-level toxicant exposures stimulate tissue growth and responsiveness…”
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Preconception paternal ethanol exposures induce alcohol-related craniofacial growth deficiencies in fetal offspring
Published in The Journal of clinical investigation (01-06-2023)Get full text
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Maternal background alters the penetrance of growth phenotypes and sex‐specific placental adaptation of offspring sired by alcohol‐exposed males
Published in The FASEB journal (01-12-2021)“…Epigenetic mechanisms of paternal inheritance are an emerging area of interest in our efforts to understand fetal alcohol spectrum disorders. In rodent models…”
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Preconception paternal alcohol exposure decreases IVF embryo survival and pregnancy success rates in a mouse model
Published in Molecular human reproduction (31-01-2023)“…Increasingly, couples struggling with fertility turn to assisted reproductive techniques, including IVF, to have children. Despite the demonstrated influence…”
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Over a decade of field physiology reveals life-history specific strategies to drought in garter snakes ( Thamnophis legans )
Published in Proceedings of the Royal Society. B, Biological sciences (26-01-2022)“…Changing climates and severe weather events can affect population viability. Individuals need to buffer such negative fitness consequences through…”
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Alterations in sperm RNAs persist after alcohol cessation and correlate with epididymal mitochondrial dysfunction
Published in Andrology (Oxford) (01-07-2024)“…Background Chronic preconception paternal alcohol use adversely modifies the sperm epigenome, inducing fetoplacental and craniofacial growth defects in the…”
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Parental Alcohol Exposures Associate with Lasting Mitochondrial Dysfunction and Accelerated Aging in a Mouse Model
Published in Aging and disease (27-07-2024)“…Although detrimental changes in mitochondrial morphology and function are widely described symptoms of fetal alcohol exposure, no studies have followed these…”
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Abstract 6458: Maternal and paternal alcohol exposures program higher incidence of hepatocellular carcinoma in offspring
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Environmental exposures during development are known to influence adult health and disease. Specifically, early developmental exposures have been shown to…”
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Preconception paternal alcohol exposure decreases IVF embryo survival and pregnancy success rates in a mouse model
Published in Molecular human reproduction (01-02-2023)Get full text
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