Search Results - "Basavappa, Ravi"
-
1
Direct Determination of Thiol pKa by Isothermal Titration Microcalorimetry
Published in Journal of the American Chemical Society (01-09-2004)“…Knowledge of the acid dissociation constant (pKa) of a molecule is a critical step toward understanding its structure and reactivity. Current methods for pKa…”
Get full text
Journal Article -
2
The Crystal Structure of Human Cyclin B
Published in Cell cycle (Georgetown, Tex.) (01-06-2007)“…Cyclin B is the key regulatory protein controlling mitosis in all eukaryotes, where it binds cyclin-dependent kinase, cdk1, forming a complex which initiates…”
Get full text
Journal Article -
3
Structural and Functional Analysis of the Human Mitotic-specific Ubiquitin-conjugating Enzyme, UbcH10
Published in The Journal of biological chemistry (14-06-2002)“…Cell cycle progression is controlled at several different junctures by the targeted destruction of cell cycle regulatory proteins. These carefully orchestrated…”
Get full text
Journal Article -
4
The regions of securin and cyclin B proteins recognized by the ubiquitination machinery are natively unfolded
Published in FEBS letters (11-09-2002)“…The proteins securin and cyclin B are destroyed in mitosis by the ubiquitin/proteasome system. This destruction is important to mitotic progression. The…”
Get full text
Journal Article -
5
Poliovirus Mutants at Histidine 195 of VP2 Do Not Cleave VP0 into VP2 and VP4
Published in Journal of Virology (01-11-1999)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
6
Structural Features of Transcription Factor IIIA Bound to a Nucleosome in Solution
Published in Molecular and Cellular Biology (01-01-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
7
The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain
Published in Nature (London) (11-08-1988)“…The glucocorticoid receptor enhances or represses transcription by binding to specific DNA sequences termed glucocorticoid response elements, or GREs. Studies…”
Get full text
Journal Article -
8
The Poliovirus Empty Capsid Specifically Recognizes the Poliovirus Receptor and Undergoes Some, but Not All, of the Transitions Associated with Cell Entry
Published in Journal of Virology (01-09-1998)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
9
Direct Determination of Thiol pK a by Isothermal Titration Microcalorimetry
Published in Journal of the American Chemical Society (01-09-2004)“…Knowledge of the acid dissociation constant (pK a) of a molecule is a critical step toward understanding its structure and reactivity. Current methods for pK a…”
Get full text
Journal Article -
10
The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox
Published in Nature methods (01-10-2016)“…In 2010, the National Institutes of Health launched a pilot program to generate and distribute high-quality affinity reagents against human transcription…”
Get full text
Journal Article -
11
NIGMS PSI:Biology Initiative – Enabling High‐Throughput Structural Biology and Structural Genomics
Published in The FASEB journal (01-04-2011)“…The National Institute of General Medical Sciences has announced PSI:Biology to continue the development of high‐throughput structural biology methods and…”
Get full text
Journal Article -
12
15 N Relaxation Studies of Apo-Mts1: A Dynamic S100 Protein
Published in Biochemistry (Easton) (01-07-2008)Get full text
Journal Article -
13
NIGMS PSI:Biology Initiative -- High-Throughput-Enabled Structural Biology
Published in Biophysical journal (01-01-2010)Get full text
Journal Article -
14
super(15)N Relaxation Studies of Apo-Mts1: A Dynamic S100 Protein
Published in Biochemistry (Easton) (01-01-2008)“…Mts1 is a member of the S100 family of EF-hand calcium-binding proteins. Like most S100 proteins, Mts1 exists as a dimer in solution and contains one canonical…”
Get full text
Journal Article -
15
NIGMS PSI:Biology Initiative ‐ Enabling High‐Throughput Structural Biology and Structural Genomics
Published in The FASEB journal (01-04-2010)“…The new Protein Structure Initiative (PSI:Biology) to be funded by NIGMS beginning July, 2010 will apply high‐throughput structural methods to important…”
Get full text
Journal Article -
16
Defining and solving the essential protein–protein interactions in HIV infection
Published in Journal of structural biology (01-05-2007)“…The structure determination of macromolecular complexes is entering a new era. The methods of optical microscopy, electron microscopy, X-ray crystallography,…”
Get full text
Journal Article -
17
15N Relaxation Studies of Apo-Mts1: A Dynamic S100 Protein
Published in Biochemistry (Easton) (22-07-2008)“…Mts1 is a member of the S100 family of EF-hand calcium-binding proteins. Like most S100 proteins, Mts1 exists as a dimer in solution and contains one canonical…”
Get full text
Journal Article -
18
The Active Site Cysteine of Ubiquitin-Conjugating Enzymes Has a Significantly Elevated pK a: Functional Implications
Published in Biochemistry (Easton) (20-12-2005)“…Ubiquitin-conjugating enzymes (E2s or Ubcs) are essential components in the ubiquitination apparatus. These enzymes accept ubiquitin from an E1 enzyme and…”
Get full text
Journal Article -
19
The Active Site Cysteine of Ubiquitin-Conjugating Enzymes Has a Significantly Elevated pKa: Functional Implications
Published in Biochemistry (Easton) (20-12-2005)“…Ubiquitin-conjugating enzymes (E2s or Ubcs) are essential components in the ubiquitination apparatus. These enzymes accept ubiquitin from an E1 enzyme and…”
Get full text
Journal Article -
20
The Active Site Cysteine of Ubiquitin-Conjugating Enzymes Has a Significantly Elevated p K a : Functional Implications
Published in Biochemistry (Easton) (01-12-2005)Get full text
Journal Article