Search Results - "Basavan, Duraiswamy"
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Implications of fractalkine on glial function, ablation and glial proteins/receptors/markers—understanding its therapeutic usefulness in neurological settings: a narrative review
Published in Future journal of pharmaceutical sciences (01-12-2022)“…Background Fractalkine (CX3CL1) is a chemokine predominantly released by neurons. As a signaling molecule, CX3CL1 facilitates talk between neurons and glia…”
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Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease
Published in Journal of pharmacy and pharmacology (01-12-2013)“…Objectives Adults who develop type 2 diabetes (T2D) at later stages are at a higher risk of developing Alzheimer's disease (AD). Pharmacological agents such as…”
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A Review on Plant-Derived Immunomodulatory Agents: Hopes as an Alternative Medicine in the Management of Immune-Related Disorders
Published in Traditional and integrative medicine (27-06-2023)“…In humans, the immune system serves as a protective barrier against infection; however, when the immune system is out of balance, it can harm the host…”
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Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection
Published in Current drug targets (01-01-2022)“…Angiotensin-converting enzyme 2 (ACE2) has been reported as a portal for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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Dipeptidyl peptidase-IV inhibitory action of Calebin A: An in silico and in vitro analysis
Published in Journal of ayurveda and integrative medicine (01-10-2021)“…Dipeptidyl peptidase-IV (DPP-IV) inhibitors, the enhancers of incretin are used for the treatment of diabetes. The non-glycaemic actions of these drugs (under…”
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Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2022)“…Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay…”
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Phytoconstituents and their Possible Mechanistic Profile for Alzheimer's Disease - A Literature Review
Published in Current drug targets (01-01-2019)“…Memory is an associated part of life without which livelihood of a human being becomes miserable. As the global aged population is increasing tremendously,…”
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Assessment of inhibitory potential of Pothos scandens L. on ovalbumin-induced airway hyperresponsiveness in balb/c mice
Published in International immunopharmacology (01-01-2014)“…Pothos scandens L. was used in Indian traditional medicine as an antiasthmatic drug. The ethanolic and aqueous extracts were prepared with aerial parts of P…”
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Reversal mechanism of multidrug-resistant cancer cells by lectin as chemo-adjuvant and targeted therapy- a systematic review
Published in Phytomedicine (Stuttgart) (01-01-2024)“…Cancer is characterized as the leading cause of death, and the susceptibility of cancer cells to develop resistance due to long-term exposure to complementary…”
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Jackfruit waste: an invented anticancer therapy using Jacalin lectin from jackfruit seed
Published in Anti-cancer drugs (01-11-2023)“…Every food source contains both edible and inedible waste components. Millions of tonnes of trash from the food business are made from fruits, and these wastes…”
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Ethnopharmacological validation of Karkataka Taila-An edible crab Rasayana in rotenone-induced in vitro and in vivo models of Parkinson's disease
Published in Journal of ethnopharmacology (05-12-2024)“…‘Karkataka Taila (KT), an ancient Ayurvedic Rasayana comprising the edible freshwater crab Scylla serrata Forskal flesh, is still used by local traditional…”
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NOVEL DUAL GLP-1 AND GIP RECEPTOR ANALOG ATTENUATES HIGH-FAT-DIET-INDUCED DISEASE PROGRESSION IN 3XTG-AD MICE
Published in Alzheimer's & dementia (01-07-2017)Get full text
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A combination of resveratrol and 3,3'-diindolylmethane, a potent radioprotector
Published in International journal of radiation biology (01-06-2018)“…Exposure to ionizing radiation causes damage to the genomic integrity and stability of the cell. Though a large number of molecules have been studied for their…”
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Saxagliptin: A dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease
Published in Neuropharmacology (01-09-2013)“…Type 2 diabetes (T2D) is one of the major risk factors associated with Alzheimer's disease (AD). Recent studies have found similarities in molecular mechanisms…”
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DPP4 Inhibitors Can Be a Drug of Choice for Type 3 Diabetes: A Mini Review
Published in American Journal of Alzheimer's Disease & Other Dementias (01-11-2017)“…As well known to the scientific community, Alzheimer’s disease (AD) is an irreversible neurodegenerative disease that ends up with impairment of memory and…”
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Pterocarpus marsupium, a dipepidyl peptidase-4 inhibitor, mitigates pathological features of Alzheimer's disease
Published in Alzheimer's & dementia (01-07-2015)Get full text
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P4‐157: Pterocarpus marsupium, a dipepidyl peptidase‐4 inhibitor, mitigates pathological features of Alzheimer's disease
Published in Alzheimer's & dementia (01-07-2015)Get full text
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Possible role of DPP4 inhibitors to promote hippocampal neurogenesis in Alzheimer's disease
Published in Journal of drug targeting (14-09-2018)“…As well-known to the scientific community, Alzheimer's disease (AD) is an irreversible neurodegenerative disease that ends up with impairment of memory and…”
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Dipeptidyl peptidase-4 inhibition by Pterocarpus marsupium and Eugenia jambolana ameliorates streptozotocin induced Alzheimer's disease
Published in Behavioural brain research (01-07-2014)“…•Examined the neuroprotective effect of Pterocarpus marsupium and Eugenia jambolana.•Streptozotocin intracerebrally causes cognitive deficits in Alzheimer's…”
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Development and biological evaluation of Gymnema sylvestre extract-loaded nonionic surfactant-based niosomes
Published in Nanomedicine (London, England) (01-08-2013)“…To develop and characterize Gymnema sylvestre extract-loaded niosomes using nonionic surfactants, and to evaluate their antihyperglycemic efficacy in…”
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