Search Results - "Basant, Angika"
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1
The relative binding position of Nck and Grb2 adaptors impacts actin-based motility of Vaccinia virus
Published in eLife (07-07-2022)“…Phosphotyrosine (pTyr) motifs in unstructured polypeptides orchestrate important cellular processes by engaging SH2-containing adaptors to assemble complex…”
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Journal Article -
2
The amount of Nck rather than N-WASP correlates with the rate of actin-based motility of Vaccinia virus
Published in Microbiology spectrum (12-12-2023)“…Vaccinia virus is a large double-stranded DNA virus and a close relative of Mpox and Variola virus, the causative agent of smallpox. During infection, Vaccinia…”
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3
Kinesin-1 transports morphologically distinct intracellular virions during vaccinia infection
Published in Journal of cell science (01-03-2023)“…Intracellular mature viruses (IMVs) are the first and most abundant infectious form of vaccinia virus to assemble during its replication cycle. IMVs can…”
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4
A GAP that Divides [version 1; peer review: 3 approved]
Published in F1000 research (2017)“…Cytokinesis in metazoan cells is mediated by an actomyosin-based contractile ring that assembles in response to activation of the small GTPase RhoA. The…”
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5
Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression
Published in Malaria journal (23-04-2010)“…Metabolic changes in the host in response to Plasmodium infection play a crucial role in the pathogenesis of malaria. Alterations in metabolism of male and…”
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6
Spatiotemporal Regulation of RhoA during Cytokinesis
Published in Current biology (07-05-2018)“…The active form of the small GTPase RhoA is necessary and sufficient for formation of a cytokinetic furrow in animal cells. Despite the conceptual simplicity…”
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7
Global host metabolic response to Plasmodium vivax infection: a 1H NMR based urinary metabonomic study
Published in Malaria journal (23-12-2011)“…Plasmodium vivax is responsible for the majority of malarial infection in the Indian subcontinent. This species of the parasite is generally believed to cause…”
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Journal Article -
8
Liver Metabolic Alterations and Changes in Host Intercompartmental Metabolic Correlation during Progression of Malaria
Published in Journal of Parasitology Research (2011)“…1H NMR-based metabonomics was used to investigate the multimodal response of mice to malarial parasite infection by P. berghei ANKA. Liver metabolism was…”
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9
CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes
Published in EMBO reports (09-08-2024)“…The inhibitors, CK-666 and CK-869, are widely used to probe the function of Arp2/3 complex mediated actin nucleation in vitro and in cells. However, in…”
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10
Aurora B Kinase Promotes Cytokinesis by Inducing Centralspindlin Oligomers that Associate with the Plasma Membrane
Published in Developmental cell (20-04-2015)“…In metazoans, cytokinesis is triggered by activation of the GTPase RhoA at the equatorial plasma membrane. ECT-2, the guanine nucleotide exchange factor (GEF)…”
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11
PLK1 plays dual roles in centralspindlin regulation during cytokinesis
Published in The Journal of cell biology (01-04-2019)“…Cytokinesis begins upon anaphase onset. An early step involves local activation of the small GTPase RhoA, which triggers assembly of an actomyosin-based…”
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12
Positioning the plane of cell division: The role of cortical centralspindlin
Published 2016“…In metazoans, cytokinesis is triggered by activation of the GTPase RhoA at the equatorial plasma membrane. ECT-2, the guanine nucleotide exchange factor (GEF)…”
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Dissertation -
13
Global host metabolic response to Plasmodium vivax infection: a H NMR based urinary metabonomic study
Published in Malaria journal (23-12-2011)“…Background Plasmodium vivax is responsible for the majority of malarial infection in the Indian subcontinent. This species of the parasite is generally…”
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Journal Article