Search Results - "Bas, Yuliia"

3,3-Difluorooxetane - A Versatile Functional Group for Bioisosteric Replacements in Drug Discovery by Liashuk, Oleksandr S, Fedinchyk, Anastasiya, Melnykov, Kostiantyn P, Herasymchuk, Maksym, Alieksieieva, Diana, Lesyk, Dmytro, Bas, Yuliia P, Keda, Tetiana Ye, Yatsymyrskiy, Andriy V, Holota, Yuliia, Borysko, Petro, Yarmolchuk, Volodymyr S, Grygorenko, Oleksandr O

“…Functional group (FG) is one of the cornerstone concepts in organic chemistry and related areas. The wide spread of bioisosterism ideas in medicinal chemistry…”
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2-Oxabicyclo[2.2.2]octane as a new bioisostere of the phenyl ring by Levterov, Vadym V., Panasiuk, Yaroslav, Sahun, Kateryna, Stashkevych, Oleksandr, Badlo, Valentyn, Shablykin, Oleh, Sadkova, Iryna, Bortnichuk, Lina, Klymenko-Ulianov, Oleksii, Holota, Yuliia, Lachmann, Leonid, Borysko, Petro, Horbatok, Kateryna, Bodenchuk, Iryna, Bas, Yuliia, Dudenko, Dmytro, Mykhailiuk, Pavel K.

“…The phenyl ring is a basic structural element in chemistry. Here, we show the design, synthesis, and validation of its new saturated bioisostere with improved…”
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