Search Results - "Bartz, Jason C."

Cellular and Molecular Mechanisms of Prion Disease by Sigurdson, Christina J, Bartz, Jason C, Glatzel, Markus

“…Prion diseases are rapidly progressive, incurable neurodegenerative disorders caused by misfolded, aggregated proteins known as prions, which are uniquely…”
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Investigation of Bovine Serum Albumin (BSA) Attachment onto Self-Assembled Monolayers (SAMs) Using Combinatorial Quartz Crystal Microbalance with Dissipation (QCM-D) and Spectroscopic Ellipsometry (SE) by Phan, Hanh T M, Bartelt-Hunt, Shannon, Rodenhausen, Keith B, Schubert, Mathias, Bartz, Jason C

“…Understanding protein adsorption kinetics to surfaces is of importance for various environmental and biomedical applications. Adsorption of bovine serum…”
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Occurrence, transmission, and zoonotic potential of chronic wasting disease by Saunders, Samuel E, Bartelt-Hunt, Shannon L, Bartz, Jason C

“…Chronic wasting disease (CWD) is a fatal, transmissible prion disease that affects captive and free-ranging deer, elk, and moose. Although the zoonotic…”
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Minor prion substrains overcome transmission barriers by Steadman, Benjamin S, Bian, Jifeng, Shikiya, Ronald A, Bartz, Jason C

“…Mammalian prion diseases are infectious neurodegenerative diseases caused by the self-templating form of the prion protein PrP . Much evidence supports the…”
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Sensitive detection of chronic wasting disease prions recovered from environmentally relevant surfaces by Yuan, Qi, Rowden, Gage, Wolf, Tiffany M., Schwabenlander, Marc D., Larsen, Peter A., Bartelt-Hunt, Shannon L., Bartz, Jason C.

“…[Display omitted] •An innovative method for prion recovery from swabs was developed.•Recovery of prions decreased as swab-drying time was increased.•Recovery…”
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Prion protein amino acid sequence influences formation of authentic synthetic PrPSc by Block, Alyssa J., York, Taylor C., Benedict, Romilly, Ma, Jiyan, Bartz, Jason C.

“…Synthetic prions, generated de novo from minimal, non-infectious components, cause bona fide prion disease in animals. Transmission of synthetic prions to…”
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Strain-Specific Targeting and Destruction of Cells by Prions by Simmons, Sara M, Bartz, Jason C

“…Prion diseases are caused by the disease-specific self-templating infectious conformation of the host-encoded prion protein, PrP . Prion strains are…”
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Evidence for preexisting prion substrain diversity in a biologically cloned prion strain by Gunnels, Tess, Shikiya, Ronald A, York, Taylor C, Block, Alyssa J, Bartz, Jason C

“…Prion diseases are a group of inevitably fatal neurodegenerative disorders affecting numerous mammalian species, including Sapiens. Prions are composed of…”
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Independent amplification of co-infected long incubation period low conversion efficiency prion strains by Eckland, Thomas E, Shikiya, Ronald A, Bartz, Jason C

“…Prion diseases are caused by a misfolded isoform of the prion protein, PrPSc. Prion strains are hypothesized to be encoded by strain-specific conformations of…”
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Expression of the cellular prion protein by mast cells in the human carotid body by Sweetland, Gregory D., Eggleston, Connor, Bartz, Jason C., Mathiason, Candace K., Kincaid, Anthony E.

“…Prion diseases are fatal neurologic disorders that can be transmitted by blood transfusion. The route for neuroinvasion following exposure to infected blood is…”
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In vitro detection of prionemia in TSE-infected cervids and hamsters by Elder, Alan M, Henderson, Davin M, Nalls, Amy V, Wilham, Jason M, Caughey, Byron W, Hoover, Edward A, Kincaid, Anthony E, Bartz, Jason C, Mathiason, Candace K

“…Blood-borne transmission of infectious prions during the symptomatic and asymptomatic stages of disease occurs for both human and animal transmissible…”
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Transport of Prions in the Peripheral Nervous System: Pathways, Cell Types, and Mechanisms by Koshy, Sam M, Kincaid, Anthony E, Bartz, Jason C

“…Prion diseases are transmissible protein misfolding disorders that occur in animals and humans where the endogenous prion protein, PrP , undergoes a…”
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Prion replication without host adaptation during interspecies transmissions by Bian, Jifeng, Khaychuk, Vadim, Angers, Rachel C., Fernández-Borges, Natalia, Vidal, Enric, Meyerett-Reid, Crystal, Kim, Sehun, Calvi, Carla L., Bartz, Jason C., Hoover, Edward A., Agrimi, Umberto, Richt, Jürgen A., Castilla, Joaquín, Telling, Glenn C.

“…Adaptation of prions to new species is thought to reflect the capacity of the host-encoded cellular form of the prion protein (PrPC) to selectively propagate…”
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From Slow Viruses to Prions by Bartz, Jason C

“…What we found was that when a single prion strain was inoculated into a new host species, more than one strain would emerge. [...]changes in the conformation…”
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Expression of the cellular prion protein by mast cells in white-tailed deer carotid body, cervical lymph nodes and ganglia by Kincaid, Anthony E, Denkers, Nathaniel D, McNulty, Erin E, Kraft, Caitlyn N, Bartz, Jason C, Mathiason, Candace K

“…Chronic wasting disease (CWD) is a transmissible and fatal prion disease that affects cervids. While both oral and nasal routes of exposure to prions cause…”
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The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease by Ayers, Jacob I, Schutt, Charles R, Shikiya, Ronald A, Aguzzi, Adriano, Kincaid, Anthony E, Bartz, Jason C

“…Prion strains are characterized by differences in the outcome of disease, most notably incubation period and neuropathological features. While it is…”
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Efficient interspecies transmission of synthetic prions by Block, Alyssa J, Shikiya, Ronald A, Eckland, Thomas E, Kincaid, Anthony E, Walters, Ryan W, Ma, Jiyan, Bartz, Jason C

“…Prions are comprised solely of PrP Sc , the misfolded self-propagating conformation of the cellular protein, PrP C . Synthetic prions are generated in vitro…”
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The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease by Ayers, Jacob I, Schutt, Charles R, Shikiya, Ronald A, Aguzzi, Adriano, Kincaid, Anthony E, Bartz, Jason C

“…Prion strains are characterized by differences in the outcome of disease, most notably incubation period and neuropathological features. While it is…”
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PrPSc formation and clearance as determinants of prion tropism by Shikiya, Ronald A, Langenfeld, Katie A, Eckland, Thomas E, Trinh, Jonathan, Holec, Sara A M, Mathiason, Candace K, Kincaid, Anthony E, Bartz, Jason C

“…Prion strains are characterized by strain-specific differences in neuropathology but can also differ in incubation period, clinical disease, host-range and…”
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In Vitro Generation of High-Titer Prions by Shikiya, Ronald A, Bartz, Jason C

“…Prions are composed mainly, if not entirely, of PrPSc, an infectious misfolded isoform of PrPC, the normal isoform of the prion protein. Here we show that…”
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