Search Results - "Bartunková, Jirina"

Induction of Tolerance and Immunity by Dendritic Cells: Mechanisms and Clinical Applications by Fucikova, Jitka, Palova-Jelinkova, Lenka, Bartunkova, Jirina, Spisek, Radek

“…Dendritic cells (DCs) are key regulators of immune responses that operate at the interface between innate and adaptive immunity, and defects in DC functions…”
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Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response by FUCIKOVA, Jitka, KRALIKOVA, Petra, FIALOVA, Anna, BRTNICKY, Tomas, ROB, Lukas, BARTUNKOVA, Jirina, SPISEK, Radek

“…Immunogenic cell death is characterized by the early surface exposure of chaperones including calreticulin and HSPs, which affect dendritic cell (DC)…”
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The WNT/β-catenin signaling inhibitor XAV939 enhances the elimination of LNCaP and PC-3 prostate cancer cells by prostate cancer patient lymphocytes in vitro by Stakheev, Dmitry, Taborska, Pavla, Strizova, Zuzana, Podrazil, Michal, Bartunkova, Jirina, Smrz, Daniel

“…Upregulated Wnt/β-catenin signaling is associated with increased cancer cell resistance and cancer cell-elicited immunosuppression. In non-neoplastic immune…”
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Thapsigargin-Stimulated LAD2 Human Mast Cell Line Is a Potent Cellular Adjuvant for the Maturation of Monocyte-Derived Dendritic Cells for Adoptive Cellular Immunotherapy by Taborska, Pavla, Stakheev, Dmitry, Bartunkova, Jirina, Smrz, Daniel

“…The preparation of dendritic cells (DCs) for adoptive cellular immunotherapy (ACI) requires the maturation of ex vivo-produced immature(i) DCs. This maturation…”
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The TRAIL in the Treatment of Human Cancer: An Update on Clinical Trials by Snajdauf, Martin, Havlova, Klara, Vachtenheim, Jr, Jiri, Ozaniak, Andrej, Lischke, Robert, Bartunkova, Jirina, Smrz, Daniel, Strizova, Zuzana

“…TRAIL (tumor-necrosis factor related apoptosis-inducing ligand, CD253) and its death receptors TRAIL-R1 and TRAIL-R2 selectively trigger the apoptotic cell…”
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High hydrostatic pressure induces immunogenic cell death in human tumor cells by Fucikova, Jitka, Moserova, Irena, Truxova, Iva, Hermanova, Ivana, Vancurova, Irena, Partlova, Simona, Fialova, Anna, Sojka, Ludek, Cartron, Pierre‐Francois, Houska, Milan, Rob, Lukas, Bartunkova, Jirina, Spisek, Radek

“…Recent studies have identified molecular events characteristic of immunogenic cell death (ICD), including surface exposure of calreticulin (CRT), the heat…”
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Tumoral and paratumoral NK cells and CD8+ T cells of esophageal carcinoma patients express high levels of CD47 by Strizova, Zuzana, Vachtenheim, Jiri, Snajdauf, Martin, Lischke, Robert, Bartunkova, Jirina, Smrz, Daniel

“…In a limited number of human malignancies, anti-CD47 therapy leads to the rapid clearance of tumor cells by macrophages. In esophageal squamous cell carcinoma,…”
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Mast Cells and Dendritic Cells as Cellular Immune Checkpoints in Immunotherapy of Solid Tumors by Kalkusova, Katerina, Smite, Sindija, Darras, Elea, Taborska, Pavla, Stakheev, Dmitry, Vannucci, Luca, Bartunkova, Jirina, Smrz, Daniel

“…The immune checkpoint inhibitors have revolutionized cancer immunotherapy. These inhibitors are game changers in many cancers and for many patients, sometimes…”
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Impaired Proliferation of CD8 + T Cells Stimulated with Monocyte-Derived Dendritic Cells Previously Matured with Thapsigargin-Stimulated LAD2 Human Mast Cells by Kalkusova, Katerina, Taborska, Pavla, Stakheev, Dmitry, Rataj, Michal, Smite, Sindija, Darras, Elea, Albo, Julia, Bartunkova, Jirina, Vannucci, Luca, Smrz, Daniel

“…CD8 T cells are essential for adaptive immunity against infection and tumors. Their ability to proliferate after stimulation is crucial to their functionality…”
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Clinical Outcome of Coronavirus Disease 2019 in Patients with Primary Antibody Deficiencies by Milota, Tomas, Smetanova, Jitka, Bartunkova, Jirina

“…In 2019, the novel coronavirus, SARS-CoV-2, caused a worldwide pandemic, affecting more than 630 million individuals and causing 6.5 million deaths. In the…”
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LL-37 as a Powerful Molecular Tool for Boosting the Performance of Ex Vivo-Produced Human Dendritic Cells for Cancer Immunotherapy by Stakheev, Dmitry, Taborska, Pavla, Kalkusova, Katerina, Bartunkova, Jirina, Smrz, Daniel

“…Ex vivo-produced dendritic cells (DCs) constitute the core of active cellular immunotherapy (ACI) for cancer treatment. After many disappointments in clinical…”
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Effectiveness and Durability of mRNA Vaccine-Induced SARS-CoV-2-Specific Humoral and Cellular Immunity in Severe Asthma Patients on Biological Therapy by Podrazil, Michal, Taborska, Pavla, Stakheev, Dmitry, Rataj, Michal, Lastovicka, Jan, Vlachova, Alena, Pohunek, Petr, Bartunkova, Jirina, Smrz, Daniel

“…Coronavirus disease 2019 (COVID-19) vaccines effectively elicit humoral and cellular immunity against severe acute respiratory syndrome coronavirus 2…”
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CD4 + T Cells of Prostate Cancer Patients Have Decreased Immune Responses to Antigens Derived From SARS-CoV-2 Spike Glycoprotein by Taborska, Pavla, Strizova, Zuzana, Stakheev, Dmitry, Sojka, Ludek, Bartunkova, Jirina, Smrz, Daniel

“…The adaptive immune response to severe acute respiratory coronavirus 2 (SARS-CoV-2) is important for vaccine development and in the recovery from coronavirus…”
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The paratumoral immune cell signature reveals the potential for the implementation of immunotherapy in esophageal carcinoma patients by Strizova, Zuzana, Snajdauf, Martin, Stakheev, Dmitry, Taborska, Pavla, Vachtenheim, Jiri, Biskup, Jan, Lischke, Robert, Bartunkova, Jirina, Smrz, Daniel

“…Purpose Esophageal cancer (EC) is one of the most lethal gastrointestinal malignancies. Immunotherapy is a promising treatment modality for this disease…”
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The expression profiles of CD47 in the tumor microenvironment of salivary gland cancers: a next step in histology-driven immunotherapy by Votava, Michal, Bartolini, Robin, Capkova, Linda, Smetanova, Jitka, Jiri, Vachtenheim, Kuchar, Martin, Kalfert, David, Plzak, Jan, Bartunkova, Jirina, Strizova, Zuzana

“…Abstract Background Salivary gland carcinomas (SGC) are extremely rare malignancies with only limited treatment options for the metastatic phase of the…”
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Immunogenic properties of nickel-doped maghemite nanoparticles and the implication for cancer immunotherapy by Rajsiglova, Lenka, Babic, Michal, Krausova, Katerina, Lukac, Pavol, Kalkusova, Katerina, Taborska, Pavla, Sojka, Ludek, Bartunkova, Jirina, Stakheev, Dmitry, Vannucci, Luca, Smrz, Daniel

“…Nanoparticles are commonly used in diagnostics and therapy. They are also increasingly being implemented in cancer immunotherapy because of their ability to…”
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SARS‐CoV‐2 spike glycoprotein‐reactive T cells can be readily expanded from COVID‐19 vaccinated donors by Taborska, Pavla, Lastovicka, Jan, Stakheev, Dmitry, Strizova, Zuzana, Bartunkova, Jirina, Smrz, Daniel

“…Introduction The COVID‐19 vaccine was designed to provide protection against infection by the severe respiratory coronavirus 2 (SARS‐CoV‐2) and coronavirus…”
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Distinct leukocyte populations and cytokine secretion profiles define tumoral and peritumoral areas in renal cell carcinoma by Borcinova, Martina, Bartolini, Robin, Foley, Lily Koumbas, Novak, Vojtech, Taborska, Pavla, Stakheev, Dmitry, Rataj, Michal, Smrz, Daniel, Fialova, Martina, Hacek, Jaromir, Komarc, Martin, Vesely, Stepan, Babjuk, Marek, Striz, Ilja, Bartunkova, Jirina, Buchler, Tomas, Ozaniak Strizova, Zuzana

“…•Tumor-infiltrating lymphocytes (TILs) exhibit higher cytokine production compared to peripheral TILs (pTILs) in patients with RCC.•CD8+ T cells predominantly…”
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Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors by Rozkova, Daniela, Horvath, Rudolf, Bartunkova, Jirina, Spisek, Radek

“…Glucocorticoids (GCs) are widely used as anti-inflammatory and immunosuppressive agents. Effects of GC have mainly been attributed to the suppression of T…”
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Peripheral gene signatures reveal distinct cancer patient immunotypes with therapeutic implications for autologous DC-based vaccines by Hensler, Michal, Rakova, Jana, Kasikova, Lenka, Lanickova, Tereza, Pasulka, Josef, Holicek, Peter, Hraska, Marek, Hrnciarova, Tereza, Kadlecova, Pavla, Schoenenberger, Andreu, Sochorova, Klara, Rozkova, Daniela, Sojka, Ludek, Drozenova, Jana, Laco, Jan, Horvath, Rudolf, Podrazil, Michal, Hongyan, Guo, Brtnicky, Tomas, Halaska, Michal J., Rob, Lukas, Ryska, Ales, Coosemans, An, Vergote, Ignace, Garg, Abhishek D., Cibula, David, Bartunkova, Jirina, Spisek, Radek, Fucikova, Jitka

“…Dendritic cells (DCs) have received considerable attention as potential targets for the development of novel cancer immunotherapies. However, the clinical…”
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