Search Results - "Bartunik, H. D."

The structures of HsIU and the ATP-dependent protease HsIU-HsIV by BOCHTIER, M, HARTMANN, C, HYUN KYU SONG, BOURENKOV, G. P, BARTUNIK, H. D, HUBER, R

“…The degradation of cytoplasmic proteins is an ATP-dependent process. Substrates are targeted to a single soluble protease, the 26S proteasome, in eukaryotes…”
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A Steric Mechanism for Inhibition of CO Binding to Heme Proteins by Kachalova, Galina S., Popov, Alexander N., Bartunik, Hans D.

“…The crystal structures of myoglobin in the deoxy- and carbon monoxide-ligated states at a resolution of 1.15 angstroms show that carbon monoxide binding at…”
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Structure of cytochrome c nitrite reductase by Einsle, Oliver, Kroneck, Peter M. H, Messerschmidt, Albrecht, Stach, Petra, Bourenkov, Gleb P, Bartunik, Hans D, Huber, Robert

“…The enzyme cytochrome c nitrite reductase catalyses the six-electron reduction of nitrite to ammonia as one of the key stepsin the biological nitrogen cycle,…”
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Crystal structures of the membrane-binding C2 domain of human coagulation factor V by Bode, Wolfram, Macedo-Ribeiro, Sandra, Huber, Robert, Quinn-Allen, Mary Ann, Kim, Suhng Wook, Ortel, Thomas L, Bourenkov, Gleb P, Bartunik, Hans D, Stubbs, Milton T, Kane, William H, Fuentes-Prior, Pablo

“…Rapid and controlled clot formation is achieved through sequential activation of circulating serine proteinase precursors on phosphatidylserine-rich…”
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Accuracy and precision in protein structure analysis: restrained least-squares refinement of the structure of poplar plastocyanin at 1.33 A resolution by Guss, J M, Bartunik, H D, Freeman, H C

“…The structure of the electron-transfer protein, plastocyanin (99 amino acids, one Cu atom, 10,500 Da) from poplar leaves, has been refined at 1.33 A resolution…”
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Structure of 20S proteasome from yeast at 2.4 Å resolution by GROLL, M, DITZEL, L, LÖWE, J, STOCK, D, BOCHTLER, M, BARTUNIK, H. D, HUBER, R

“…The crystal structure of the 20S proteasome from the yeast Saccharomyces cerevisiae shows that its 28 protein subunits are arranged as an (alpha1...alpha7,…”
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Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus by Soulimane, T, Buse, G, Bourenkov, G P, Bartunik, H D, Huber, R, Than, M E

“…Cytochrome c oxidase is a respiratory enzyme catalysing the energy-conserving reduction of molecular oxygen to water. The crystal structure of the…”
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Crystal structure of bovine beta-trypsin at 1.5 A resolution in a crystal form with low molecular packing density. Active site geometry, ion pairs and solvent structure by Bartunik, H D, Summers, L J, Bartsch, H H

“…The crystal structure of bovine pancreatic beta-trypsin (BPT) has been determined from a novel orthorhombic crystal form which contains substantially more…”
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Automated mounting, centering and screening of crystals for high-throughput protein crystallography by Karain, W. I., Bourenkov, G. P., Blume, H., Bartunik, H. D.

“…A fully automated system for screening protein crystals for X‐ray diffraction analysis has been designed and is being installed on the beamline BW6 at DORIS in…”
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Reversible Inhibition of Escherichia coli Inorganic Pyrophosphatase by Fluoride: Trapped Catalytic Intermediates in Cryo-crystallographic Studies by Samygina, V.R., Moiseev, V.M., Rodina, E.V., Vorobyeva, N.N., Popov, A.N., Kurilova, S.A., Nazarova, T.I., Avaeva, S.M., Bartunik, H.D.

“…Here, we describe high-resolution X-ray structures of Escherichia coli inorganic pyrophosphatase (E-PPase) complexed with the substrate, magnesium, or…”
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Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly by Kaiser, Jens T, Clausen, Tim, Bourenkow, Gleb P, Bartunik, Hans-D, Steinbacher, Stefan, Huber, Robert

“…NifS-like proteins are ubiquitous, homodimeric, proteins which belong to the α-family of pyridoxal-5′-phoshate dependent enzymes. They are proposed to donate…”
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An Extended RNA Binding Surface through Arrayed S1 and KH Domains in Transcription Factor NusA by Worbs, Michael, Bourenkov, Gleb P., Bartunik, Hans D., Huber, Robert, Wahl, Markus C.

“…The crystal structure of Thermotoga maritima NusA, a transcription factor involved in pausing, termination, and antitermination processes, reveals a…”
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Interaction between the main components of the vertebrate retinal rod phototransduction system in solutions of detergent n-nonyl-β-D-glucoside by Orlov, N. Ya, Orlova, T. G., Nezvetsky, A. R., Burstein, E. A., Bartunik, H. D.

“…cGMP-Specific phosphodiesterase (PDE6) is the key enzyme of the phototransduction system of vertebrate retinal rod outer segments (ROS). The properties of PDE…”
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Purification and crystallization of yeast hexokinase isoenzymes. Characterization of different forms by chromatofocusing by Jacob, L, Beecken, V, Bartunik, L J, Rose, M, Bartunik, H D

“…The yeast hexokinase isoenzymes PI and PII have been purified in large amounts (20 mg) from overproducing yeast strains. The purification procedures of…”
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Fast high-performance liquid chromatographic purification of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase by Jacob, L R, Vollert, H, Rose, M, Entian, K D, Bartunik, L J, Bartunik, H D

“…A procedure was established for the rapid isolation of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase (PEPCK) from an overproducing strain…”
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Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation by Aleshin, A E, Kirby, C, Liu, X, Bourenkov, G P, Bartunik, H D, Fromm, H J, Honzatko, R B

“…Hexokinase I, the pacemaker of glycolysis in brain tissue, is composed of two structurally similar halves connected by an alpha-helix. The enzyme dimerizes at…”
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Heavy riboflavin synthase from Bacillus subtilis. Particle dimensions, crystal packing and molecular symmetry by Ladenstein, R, Meyer, B, Huber, R, Labischinski, H, Bartels, K, Bartunik, H D, Bachmann, L, Ludwig, H C, Bacher, A

“…Heavy riboflavin synthase from Bacillus subtilis is an enzyme complex consisting of approximately three alpha-subunits (Mr 23.5 X 10(3)) and 60 beta-subunits…”
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Flexibility, conformational diversity and two dimerization modes in complexes of ribosomal protein L12 by Wahl, Markus C., Bourenkov, Gleb P., Bartunik, Hans D., Huber, Robert

“…Protein L12, the only multicopy component of the ribosome, is presumed to be involved in the binding of translation factors, stimulating factor‐dependent GTP…”
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The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate by Aleshin, Alexander E, Zeng, Chenbo, Bourenkov, Gleb P, Bartunik, Hans D, Fromm, Herbert J, Honzatko, Richard B

“…Background: Hexokinase l is the pacemaker of glycolysis in brain tissue. The type l isozyme exhibits unique regulatory properties in that physiological levels…”
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Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate by Aleshin, A E, Zeng, C, Bartunik, H D, Fromm, H J, Honzatko, R B

“…Hexokinase I, the pacemaker of glycolysis in brain tissue and red blood cells, is comprised of two similar domains fused into a single polypeptide chain. The…”
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