Search Results - "Bartram, James"

Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition by Hinge, Ashwini, He, Jingyi, Bartram, James, Javier, Jose, Xu, Juying, Fjellman, Ellen, Sesaki, Hiromi, Li, Tingyu, Yu, Jie, Wunderlich, Mark, Mulloy, James, Kofron, Matthew, Salomonis, Nathan, Grimes, H. Leighton, Filippi, Marie-Dominique

“…The metabolic requirements of hematopoietic stem cells (HSCs) change with their cell cycle activity. However, the underlying role of mitochondria remains…”
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Transforming growth factor-β signaling modifies the hematopoietic acute inflammatory response to drive bone marrow failure by Javier, Jose, Hinge, Ashwini, Bartram, James, Xu, Juying, Filippi, Marie-Dominique

“…Bone marrow failure syndromes are characterized by ineffective hematopoiesis due to impaired fitness of hematopoietic stem cells. They can be acquired during…”
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The challenge of supporting and monitoring safe wastewater use in agriculture in LMIC by Drechsel, Pay, Bartram, James, Qadir, Manzoor, Medlicott, Kate O.

“…Unsafe water reuse in the informal irrigation sector dominates in the Global South and requires more attention to protect food safety and public health…”
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‘WaSH Futurism’: exploring post-SDG6 targets using the Nominal Group Technique for more equitable global agenda setting by Hales, Georgia, Hasan, Bushra S. F., Balongo, Oscar, Meshvania, Jay, Sanchez-Martinez, Reychel, Shachinda, Charles, Hutchings, Paul, Bartram, James

“…Abstract Sustainable Development Goal 6 (SDG6) is grounded in human rights and derives from international policies refined over decades. We argue that much of…”
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Management of a rapidly expanding neck mass with a rare diagnosis by Bartram, James, Green, Rebecca, Paterson, Anna, Jani, Piyush

“…Malignant peripheral nerve sheath tumours are uncommon, aggressive tumours that are very rarely found in the head and neck. Whilst commonly associated with NF1…”
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The effect of fluoride on the structure, function, and proteome of a renal epithelial cell monolayer by Antonio, Ligia S., Jeggle, Pia, MacVinish, Lesley J., Bartram, James C., Miller, Henry, Jarvis, Gavin E., Levy, Flávia M., Santesso, Mariana R., Leite, Aline L., Oliveira, Rodrigo C., Buzalaf, Marília A. R., Edwardson, J. Michael

“…ABSTRACT High concentrations of fluoride in the body may cause toxic effects. Here, we investigated the effects of fluoride on the structure, function, and…”
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Spinal intradural arachnoid cysts - A multicentre case series assessing management and outcomes by Bartram, James, Mirza, Asfand Baig, Sinha, Siddharth, Boardman, Timothy, Gebreyohanes, Axumawi, Vastani, Amisha, Dyson, Edward, Russo, Vittorio, Choi, David, Kailaya-Vasan, Ahilan, Grahovac, Gordan

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3055 – MITOCHONDRIAL METABOLISM LINKS HSC DIVISIONAL HISTORY AND CELL FATE by Bartram, James, Filippi, Marie-Dominique, Xu, Juying

“…Hematopoietic stem cells are endowed with high regenerative potential but their actual self-renewal capacity is limited. Studies using the H2B-retention…”
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3024 – BRANCHED CHAIN AMINO ACID TRANSAMINASE 2 ACTIVITY CONTROLS HSC GENERATION-AGING by Bartram, James, Treichel, sydney, Xu, Juying, Filippi, Marie-Dominique

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The new metabolic needs of hematopoietic stem cells by Bartram, James, Filippi, Marie-Dominique

“…Hematopoietic stem cells (HSCs) are endowed with high regenerative potential to supply mature blood cells throughout life, under steady state or stress…”
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The Effect of SCD-1 Inhibition on Human Hematopoietic Stem Cell Mitochondrial Metabolism, Cell Proliferation, and Differentiation Potential by Perrone, Olivia, Coppola, Tiziana, Bartram, James, Nasr, Waseem, Xu, Juying, Filippi, Marie-Dominique

“…Hematopoietic stem cells (HSC) give rise to all blood lineages and sustain the production of blood cells throughout life. Due to their inherently high…”
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Divisional Memory Drives Hematopoietic Stem Cell Functional Diversity by Bartram, James, Song, Baobao (Annie), Xu, Juying, Salomonis, Nathan, Grimes, H. Leighton, Filippi, Marie-Dominique

“…Hematopoietic stem cells are endowed with high regenerative potential but their actual self-renewal capacity is limited. Studies using the H2B-retention…”
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Sinonasal carcinosarcoma with cartilaginous and rhabdomyoblastic components: A previously undescribed entity by Bartram, James, Scholfield, Daniel W, Adams, Ashok, Alusi, Ghassan, Cottom, Hannah

“…Carcinosarcomas are rare, aggressive tumors seldom found in the sinonasal region. They classically consist of sarcomatous spindle cell and carcinomatous…”
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Hematopoietic Flt3+ Multipotent Progenitors Are Organized in Discrete Functionally and Hierarchically Distinct Populations by Solomon, Michael, Song, Baobao (Annie), Govindarajah, Vinothini, Good, Samantha, Bartram, James, Cancelas, Jose, Filippi, Marie-Dominique, Salomonis, Nathan, Grimes, H. Leighton, Reynaud, Damien

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3015 – INCREASED TGFΒ SIGNALING DRIVES CHRONIC BONE MARROW FAILURE AFTER ACUTE INFLAMMATORY STRESS by Javier, Jose, Bartram, James, David, Dylan, Filippi, Marie-Dominique, Javier, Ellen, Hinge, Ashwini, Xu, Juying

“…Bone marrow failure (BMF), characterized by either an accelerated decline of hematopoietic stem cell number or chronic inability to sufficiently produce mature…”
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Surgical management and long‐term follow‐up of aberrant right coronary arteries in adults by Bartram, James, Hussain, Azhar, Chaubey, Sanjay, Mittal, Aaina, Khan, Habib, Wendler, Olaf

“…Objectives Anomalous origins of the right coronary artery (RCA) can cause ischaemia and sudden cardiac death, particularly if the RCA runs between the aorta…”
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Prognostic factors for surgically managed intramedullary spinal cord tumours: a single-centre case series by Baig Mirza, Asfand, Gebreyohanes, Axumawi, Knight, James, Bartram, James, Vastani, Amisha, Kalaitzoglou, Dimitrios, Lavrador, Jose Pedro, Kailaya-Vasan, Ahilan, Maratos, Eleni, Bell, David, Thomas, Nick, Gullan, Richard, Malik, Irfan, Grahovac, Gordan

“…Purpose Intramedullary spinal cord tumours (IMSCTs) are comparatively rare neoplasms. We present a single-centre clinical case series of adult patients with…”
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Surgical Management of Spinal Chordoma: A Systematic Review and Single-Center Experience by Baig Mirza, Asfand, Bartram, James, Okasha, Mohamed, Al Banna, Qusai, Vastani, Amisha, Maratos, Eleni, Gullan, Richard, Thomas, Nick

“…Chordoma is a rare neoplasm of the neuraxis derived from remnants of the primitive notochord. The importance of wide margins and use of adjuvant therapy in…”
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Systematic Review of Surgical Management of Spinal Intradural Arachnoid Cysts by Baig Mirza, Asfand, Bartram, James, Vastani, Amisha, Gebreyohanes, Axumawi, Al Banna, Qusai, Lavrador, Jose Pedro, Vasan, Ahilan Kailaya, Grahovac, Gordan

“…Spinal intradural arachnoid cysts (SIACs) are rare pathological lesions that can arise via outpouchings of the arachnoid layer in the spinal canal that can…”
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Slow cycling and durable Flt3+ progenitors contribute to hematopoiesis under native conditions by Solomon, Michael, Song, Baobao, Govindarajah, Vinothini, Good, Samantha, Arasu, Ashok, Hinton, E Broderick, Thakkar, Kairavee, Bartram, James, Filippi, Marie-Dominique, Cancelas, Jose A, Salomonis, Nathan, Grimes, H Leighton, Reynaud, Damien

“…The dynamics of the hematopoietic flux responsible for blood cell production in native conditions remains a matter of debate. Using CITE-seq analyses, we…”
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