Search Results - "Barton, Randall W"

Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide 1 by Yanay, Ofer, Moralejo, Daniel, Kernan, Kelly, Brzezinski, Margaret, Fuller, Jessica M., Barton, Randall W., Lernmark, Ake, Osborne, William R.

“…Background Type 1 diabetes (T1D) in both humans and BioBreeding (BB) rats is an autoimmune disease that results in complete destruction of islets and insulin…”
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Sensitivity and clinical utility of the anti-cytosolic 5′-nucleotidase 1A (cN1A) antibody test in sporadic inclusion body myositis: Report of 40 patients from a single neuromuscular center by Felice, Kevin J., Whitaker, Charles H., Wu, Qian, Larose, Daniel T., Shen, Guo, Metzger, Allan L., Barton, Randall W.

“…•We report the sensitivity and clinical utility of the anti-cN1A antibody test in sporadic inclusion body myositis (IBM).•This is a retrospective review of 40…”
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Long-term erythropoietin gene expression from transduced cells in bioisolator devices by Yanay, Ofer, Barry, Simon C, Flint, Lisa Y, Brzezinski, Margaret, Barton, Randall W, Osborne, William R A

“…Recombinant erythropoietin (EPO) is widely administered for long-term treatment of anemia associated with renal failure and other chronic diseases. The ability…”
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Nanomedicine Drug Development: A Scientific Symposium Entitled “Charting a Roadmap to Commercialization” by Finch, Gregory, Havel, Henry, Analoui, Mostafa, Barton, Randall W., Diwan, Anil R., Hennessy, Meliessa, Reddy, Vijayapal, Sadrieh, Nakissa, Tamarkin, Lawrence, Wolfgang, Marc, Yerxa, Benjamin, Zolnik, Banu, Liu, Man

“…The use of nanotechnology in medicine holds great promise for revolutionizing a variety of therapies. The past decade witnessed dramatic advancements in…”
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Studies on Proline Boronic Acid Dipeptide Inhibitors of Dipeptidyl Peptidase IV: Identification of a Cyclic Species Containing a B-N Bond by Snow, Roger J, Bachovchin, William W, Barton, Randall W, Campbell, Scot J, Coutts, Simon J, Freeman, Dorothy M, Gutheil, William G, Kelly, Terence A, Kennedy, Charles A

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Low rate of bacteremia with a subcutaneously implanted central venous access device by Nurse, Brenda A, Bonczek, Rita, Barton, Randall W, LaRose, Daniel T

“…Patients at long-term acute care hospitals (LTACs) are medically complex with multiple comorbidities and high rates of antibiotic and device use. The objective…”
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An analysis of clinical outcomes and costs of a long term acute care hospital by Votto, John J, Scalise, Paul J, Barton, Randall W, Vogel, Cristine A

“…Compare clinical outcomes and costs in a study group of long-term acute care hospital (LTCH) patients with a control group of LTCH-eligible patients in an…”
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Inhaled sodium pyruvate improved FEV1 and decreased expired breath levels of nitric oxide in patients with chronic obstructive pulmonary disease by Votto, John J, Bowen, Janet B, Barton, Randall W, Thrall, Roger S

“…Exogenously administered sodium pyruvate has a variety of biological effects including antioxidant/anti-inflammatory effects. Chronic obstructive pulmonary…”
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Glucose-regulated insulin production from genetically engineered human non-beta cells by Tatake, Revati J., O'Neill, Margaret M., Kennedy, Charles A., Reale, Virginia D., Runyan, Jacob D., Monaco, Kelli-Ann D., Yu, Kyung, Osborne, William R., Barton, Randall W., Schneiderman, Richard D.

“…In this report we describe development and characterization of four human cell lines that are able to secrete insulin and C-peptide in response to higher…”
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Structure−Activity Relationships of Boronic Acid Inhibitors of Dipeptidyl Peptidase IV. 1. Variation of the P2 Position of Xaa-boroPro Dipeptides by Coutts, Simon J, Kelly, Terence A, Snow, Roger J, Kennedy, Charles A, Barton, Randall W, Adams, Julian, Krolikowski, Dale A, Freeman, Dorothy M, Campbell, Scot J, Ksiazek, John F, Bachovchin, William W

“…A series of prolineboronic acid (boroPro) containing dipeptides were synthesized and assayed for their ability to inhibit the serine protease dipeptidyl…”
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Solution Structures of Active and Inactive Forms of the DP IV (CD26) Inhibitor Pro-boroPro Determined by NMR Spectroscopy by Sudmeier, James L, Gunther, Ulrich L, Gutheil, William G, Coutts, Simon J, Snow, Roger J, Barton, Randall W, Bachovchin, William W

“…Synthesis of the boronic acid analog of the dipeptide Pro-Pro yields a mixture of diastereomers Pro-L-boroPro and Pro-D-boroPro, one of which is a potent…”
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Binding of the T cell activation monoclonal antibody Ta1 to dipeptidyl peptidase IV by Barton, R W, Prendergast, J, Kennedy, C A

“…The monoclonal antibodies, Ta1 and IOT15, define T cell activation cell surface markers and have been assigned to the CD26 leukocyte differentiation antigen…”
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Novel NEMO/IκB Kinase and NF-κB Target Genes at the Pre-B to Immature B Cell Transition by Li, Jun, Peet, Gregory W., Balzarano, Darlene, Li, Xiang, Massa, Paul, Barton, Randall W., Marcu, Kenneth B.

“…The IκB kinase (IKK) signaling complex is responsible for activating NF-κB-dependent gene expression programs. Even though NF-κB-responsive genes are known to…”
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Immunosuppresive boronic acid dipeptides: correlation between conformation and activity by Kelly, Terence A, Adams, Julian, Bachovchin, William W, Barton, Randall W, Campbell, Scot J, Coutts, Simon J, Kennedy, Charles A, Snow, Roger J

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Beyond the medical home: Special Care Family Academy for children and youth by Thrall, Roger S, Blumberg, Jody H, Beck, Stephanie, Bourgoin, Magdalena D, Votto, John J, Barton, Randall W

“…Children and youth with special health care needs require more health care and related services and consequently incur more costs than other individuals…”
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Intracellular Distribution of Terminal Deoxynucleotidyl Transferase in Rat Bone Marrow and Thymus by Gregoire, Kathleen E., Goldschneider, Irving, Barton, Randall W., Bollum, F. J.

“…A subset of bone marrow cells that contains terminal deoxynucleotidyl transferase (DNA nucleotidylexotransferase; nucleosidetriphosphate:DNA…”
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5'-Nucleotidase Activity in Subpopulations of Rat Lymphocytes by Barton, Randall W, Goldschneider, Irving

“…Rat lymphocyte populations were assessed for 5'-nucleotidase activity by both biochemical and histochemical methods. Enzyme-specific activity was enriched in…”
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Ontogeny of Terminal Deoxynucleotidyl Transferase-Positive Cells in Lymphohemopoletic Tissues of Rat and Mouse by Gregoire, Kathleen E, Goldschneider, Irving, Barton, Randall W, Bollum, F. J

“…Abstract The ontogeny of hemopoietic cells which contain the enzyme terminal deoxynucleotidyl transferase (TdT) was studied in rats and mice. During fetal…”
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Interactions of leukocyte integrins with intercellular adhesion molecule 1 in the production of inflammatory vascular injury in vivo. The Shwartzman reaction revisited by Argenbright, L W, Barton, R W

“…We have investigated the role of leukocyte-endothelial cell interactions in a rabbit model of hemorrhagic vasculitis. Microvascular injury was produced in the…”
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Binding of human lymphocyte-specific monoclonal antibodies to common marmoset lymphoid cells by Barton, R W, Thrall, R S, Neubauer, R H

“…Commercially available monoclonal antibodies which bind to human lymphocyte subsets were screened for their ability to bind to lymphoid cells from the common…”
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