Search Results - "Bartlomiej, Przychodzen"

Genetic alterations of the cohesin complex genes in myeloid malignancies by Thota, Swapna, Viny, Aaron D., Makishima, Hideki, Spitzer, Barbara, Radivoyevitch, Tomas, Przychodzen, Bartlomiej, Sekeres, Mikkael A., Levine, Ross L., Maciejewski, Jaroslaw P.

“…Somatic cohesin mutations have been reported in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). To account for the morphologic and cytogenetic…”
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Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms by Przychodzen, Bartlomiej, Jerez, Andres, Guinta, Kathryn, Sekeres, Mikkael A., Padgett, Richard, Maciejewski, Jaroslaw P., Makishima, Hideki

“…Recently, recurrent mutations of spliceosomal genes were frequently identified in myeloid malignancies, as well as other types of cancers. One of these…”
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Rational management approach to pure red cell aplasia by Balasubramanian, Suresh Kumar, Sadaps, Meena, Thota, Swapna, Aly, Mai, Przychodzen, Bartlomiej P, Hirsch, Cassandra M, Visconte, Valeria, Radivoyevitch, Tomas, Maciejewski, Jaroslaw P

“…Pure red cell aplasia is an orphan disease, and as such lacks rationally established standard therapies. Most cases are idiopathic; a subset is…”
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Identification of potential COVID-19 treatment compounds which inhibit SARS Cov2 prototypic, Delta and Omicron variant infection by Kumar, Prabhakaran, Mathayan, Manikannan, Smieszek, Sandra P., Przychodzen, Bartlomiej P., Koprivica, Vuk, Birznieks, Gunther, Polymeropoulos, Mihael H., Prabhakar, Bellur S.

“…Recurrent waves of COVID19 remain a major global health concern. Repurposing either FDA-approved or clinically advanced drug candidates can save time and…”
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Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis by Makishima, Hideki, Visconte, Valeria, Sakaguchi, Hirotoshi, Jankowska, Anna M., Abu Kar, Sarah, Jerez, Andres, Przychodzen, Bartlomiej, Bupathi, Manoj, Guinta, Kathryn, Afable, Manuel G., Sekeres, Mikkael A., Padgett, Richard A., Tiu, Ramon V., Maciejewski, Jaroslaw P.

“…Myelodysplastic syndromes (MDSs) are chronic and often progressive myeloid neoplasms associated with remarkable heterogeneity in the histomorphology and…”
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Assessing the potential correlation of polymorphisms in the IL6R with relative IL6 elevation in severely ill COVID-19 patients by Smieszek, Sandra P., Przychodzen, Bartlomiej P., Polymeropoulos, Vasilios M., Polymeropoulos, Christos M., Polymeropoulos, Mihael H.

“…•Elevated IL-6 may play an important role in the pathophysiology of COVID-19 yet attenuated response is not seen across all severe patients.•This study reports…”
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Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting by Kubota, Yasuo, Gu, Xiaorong, Terkawi, Laila, Bodo, Juraj, Przychodzen, Bartlomiej P., Awada, Hussein, Williams, Nakisha, Gurnari, Carmelo, Kawashima, Naomi, Aly, Mai, Durmaz, Arda, Mori, Minako, Ponvilawan, Ben, Kewan, Tariq, Bahaj, Waled, Meggendorfer, Manja, Jha, Babal K., Visconte, Valeria, Rogers, Heesun J., Haferlach, Torsten, Maciejewski, Jaroslaw P.

“…PHF6 mutations ( PHF6 MT ) are identified in various myeloid neoplasms (MN). However, little is known about the precise function and consequences of PHF6 in…”
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Consequences of mutant TET2 on clonality and subclonal hierarchy by Hirsch, Cassandra M., Nazha, Aziz, Kneen, Kassy, Abazeed, Mohamed E., Meggendorfer, Manja, Przychodzen, Bartlomiej P., Nadarajah, Niroshan, Adema, Vera, Nagata, Yasunobu, Goyal, Abhinav, Awada, Hassan, Asad, Mohammad Fahad, Visconte, Valeria, Guan, Yihong, Sekeres, Mikkael A., Olinski, Ryszard, Jha, Babal Kant, LaFramboise, Thomas, Radivoyevitch, Tomas, Haferlach, Torsten, Maciejewski, Jaroslaw P.

“…Somatic mutations in TET2 are common in myelodysplastic syndromes (MDS), myeloproliferative, and overlap syndromes. TET2 mutant ( TET2 MT ) clones are also…”
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Rare germline variant contributions to myeloid malignancy susceptibility by Li, Samuel T., Wang, Janet, Wei, Ruipeng, Shi, Ruqi, Adema, Vera, Nagata, Yasunobu, Kerr, Cassandra M., Kuzmanovic, Teodora, Przychodzen, Bartlomiej, Sole, Francesc, Maciejewski, Jaroslaw P., LaFramboise, Thomas

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Elevated plasma levels of CXCL16 in severe COVID-19 patients by Smieszek, Sandra P., Polymeropoulos, Vasilios M., Polymeropoulos, Christos M., Przychodzen, Bartlomiej P., Birznieks, Gunther, Polymeropoulos, Mihael H.

“…Genome-wide association studies have recently identified 3p21.31, with lead variant pointing to the CXCR6 gene, as the strongest thus far reported…”
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Somatic SETBP1 mutations in myeloid malignancies by Makishima, Hideki, Yoshida, Kenichi, Nguyen, Nhu, Przychodzen, Bartlomiej, Sanada, Masashi, Okuno, Yusuke, Ng, Kwok Peng, Gudmundsson, Kristbjorn O, Vishwakarma, Bandana A, Jerez, Andres, Gomez-Segui, Ines, Takahashi, Mariko, Shiraishi, Yuichi, Nagata, Yasunobu, Guinta, Kathryn, Mori, Hiraku, Sekeres, Mikkael A, Chiba, Kenichi, Tanaka, Hiroko, Muramatsu, Hideki, Sakaguchi, Hirotoshi, Paquette, Ronald L, McDevitt, Michael A, Kojima, Seiji, Saunthararajah, Yogen, Miyano, Satoru, Shih, Lee-Yung, Du, Yang, Ogawa, Seishi, Maciejewski, Jaroslaw P

“…Jaroslaw Maciejewski and colleagues report whole-exome sequencing of 20 cases of myeloid malignancies, with follow up of SETBP1 in 727 further cases of myeloid…”
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Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes by Nagata, Yasunobu, Makishima, Hideki, Kerr, Cassandra M., Przychodzen, Bartlomiej P., Aly, Mai, Goyal, Abhinav, Awada, Hassan, Asad, Mohammad Fahad, Kuzmanovic, Teodora, Suzuki, Hiromichi, Yoshizato, Tetsuichi, Yoshida, Kenichi, Chiba, Kenichi, Tanaka, Hiroko, Shiraishi, Yuichi, Miyano, Satoru, Mukherjee, Sudipto, LaFramboise, Thomas, Nazha, Aziz, Sekeres, Mikkael A., Radivoyevitch, Tomas, Haferlach, Torsten, Ogawa, Seishi, Maciejewski, Jaroslaw P.

“…Myelodysplastic syndromes (MDS) arise in older adults through stepwise acquisitions of multiple somatic mutations. Here, analyzing 1809 MDS patients, we infer…”
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Genomics of therapy-related myeloid neoplasms by Kuzmanovic, Teodora, Patel, Bhumika J, Sanikommu, Srinivasa R, Nagata, Yasunobu, Awada, Hassan, Kerr, Cassandra M, Przychodzen, Bartlomiej P, Jha, Babal K, Hiwase, Devendra, Singhal, Deepak, Advani, Anjali S, Nazha, Aziz, Gerds, Aaron T, Carraway, Hetty E, Sekeres, Mikkael A, Mukherjee, Sudipto, Maciejewski, Jaroslaw P, Radivoyevitch, Tomas

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Mutation clonal burden and allogeneic hematopoietic cell transplantation outcomes in acute myeloid leukemia and myelodysplastic syndromes by Hamilton, Betty K., Rybicki, Lisa, Hirsch, Casandra, Przychodzen, Bartlomiej, Nazha, Aziz, Gerds, Aaron T., Hanna, Rabi, Kalaycio, Matt, Sekeres, Mikkael A., Sobecks, Ronald, de Lima, Marcos, Majhail, Navneet S., Maciejewski, Jaroslaw

“…Next generation sequencing (NGS) has become an important tool to inform disease risk for myeloid malignancies, however data remains conflicting regarding the…”
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Corrigendum to “Assessing the potential correlation of polymorphisms in the IL6R with relative IL6 elevation in severely ill COVID-19 patients” [Cytokine 148 (2021) 155662] by Smieszek, Sandra P., Przychodzen, Bartlomiej P., Polymeropoulos, Vasilios M., Mina, Bushra A., Polymeropoulos, Christos M., Polymeropoulos, Mihael H.

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Distinctive and common features of moderate aplastic anaemia by Patel, Bhumika J., Barot, Shimoli V., Kuzmanovic, Teodora, Kerr, Cassandra, Przychodzen, Bartlomiej P., Thota, Swapna, Lee, Sarah, Patel, Saurabh, Radivoyevitch, Tomas, Lichtin, Alan, Advani, Anjali, Kalaycio, Matt, Sekeres, Mikkael A., Carraway, Hetty E., Maciejewski, Jaroslaw P.

“…Summary The therapy algorithm for severe aplastic anaemia (sAA) is established but moderate AA (mAA), which likely reflects a more diverse pathogenic…”
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CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia by Makishima, Hideki, Jankowska, Anna M., McDevitt, Michael A., O'Keefe, Christine, Dujardin, Simon, Cazzolli, Heather, Przychodzen, Bartlomiej, Prince, Courtney, Nicoll, John, Siddaiah, Harish, Shaik, Mohammed, Szpurka, Hadrian, Hsi, Eric, Advani, Anjali, Paquette, Ronald, Maciejewski, Jaroslaw P.

“…Progression of chronic myelogenous leukemia (CML) to accelerated (AP) and blast phase (BP) is because of secondary molecular events, as well as additional…”
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PBRM1 loss in kidney cancer unbalances the proximal tubule master transcription factor hub to repress proximal tubule differentiation by Gu, Xiaorong, Enane, Francis, Tohme, Rita, Schuerger, Caroline, Radivoyevitch, Tomas, Parker, Yvonne, Zuberi, Eric, Przychodzen, Bartlomiej, Jha, Babal Kant, Lindner, Daniel, Rini, Brian, Saunthararajah, Yogen

“…PBRM1, a subunit of the PBAF coactivator complex that transcription factors use to activate target genes, is genetically inactivated in almost all clear cell…”
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Germline loss-of-function SAMD9 and SAMD9L alterations in adult myelodysplastic syndromes by Nagata, Yasunobu, Narumi, Satoshi, Guan, Yihong, Przychodzen, Bartlomiej P., Hirsch, Cassandra M., Makishima, Hideki, Shima, Hirohito, Aly, Mai, Pastor, Victor, Kuzmanovic, Teodora, Radivoyevitch, Tomas, Adema, Vera, Awada, Hassan, Yoshida, Kenichi, Li, Samuel, Sole, Francesc, Hanna, Rabi, Jha, Babal K., LaFramboise, Thomas, Ogawa, Seishi, Sekeres, Mikkael A., Wlodarski, Marcin W., Cammenga, Jörg, Maciejewski, Jaroslaw P.

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Genomic and phenotypic characterization of Investigator Global Assessment (IGA) scale-based endotypes in atopic dermatitis by Smieszek, Sandra P., Przychodzen, Bartlomiej, Welsh, Sarah E., Brzezynski, Jennifer L., Kaden, Alyssa R., Mohrman, Michael, Wang, Jingyuan, Xiao, Changfu, Ständer, Sonja, Birznieks, Gunther, Polymeropoulos, Christos, Polymeropoulos, Mihael H.

“…[Display omitted]…”
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