Search Results - "Bartley, F"
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Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome
Published in Journal of neurophysiology (01-11-2008)“…University of Texas Southwestern Medical Center, Department of Neuroscience, Dallas, Texas Submitted 8 July 2008; accepted in final form 4 September 2008…”
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2
Endogenously Released Neuropeptide Y Suppresses Hippocampal Short-Term Facilitation and Is Impaired by Stress-Induced Anxiety
Published in The Journal of neuroscience (04-01-2017)“…Neuropeptide Y (NPY) has robust anxiolytic properties and is reduced in patients with anxiety disorders. However, the mechanisms by which NPY modulates circuit…”
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3
Prefrontal cortex-dependent innate behaviors are altered by selective knockdown of Gad1 in neuropeptide Y interneurons
Published in PloS one (19-07-2018)“…GABAergic dysfunction has been implicated in a variety of neurological and psychiatric disorders, including anxiety disorders. Anxiety disorders are the most…”
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4
Feasibility of cerium-doped LSO particles as a scintillator for x-ray induced optogenetics
Published in Journal of neural engineering (27-04-2021)“…Non-invasive light delivery into the brain is needed for optogenetics to avoid physical damage. An innovative strategy could employ x-ray activation of…”
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5
Perceptions and the role of group exercise among New York City adults, 2010–2011: An examination of interpersonal factors and leisure-time physical activity
Published in Preventive medicine (01-03-2015)“…Abstract Objective To examine associations of descriptive norms (i.e., behaviors of social group members) and exercising ‘with a partner’ or ‘as a part of a…”
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Command, control and communication (C3) during the COVID-19 pandemic; adapting a military framework to crisis response in a tertiary UK critical care centre
Published in Journal of the Intensive Care Society (01-05-2022)“…The COVID-19 pandemic of 2020 imposed significant strain on critical care services worldwide. The South London region experienced the largest numbers of…”
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Transcriptional dysregulation causes altered modulation of inhibition by haloperidol
Published in Neuropharmacology (01-12-2016)“…Many neuropsychiatric and neurodevelopmental disorders such as schizophrenia and autism involve interneuron transcriptional dysregulation. The transcriptional…”
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8
Differential Activity-Dependent, Homeostatic Plasticity of Two Neocortical Inhibitory Circuits
Published in Journal of neurophysiology (01-10-2008)“…1 University of Texas, Southwestern Medical Center, Department of Neuroscience, Dallas, Texas; and 2 Cold Spring Harbor Laboratory, Cold Spring Harbor, New…”
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Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex
Published in Neuroscience (20-06-2014)“…Highlights • Mice lacking PGC-1α exhibit alterations in basal inhibition in the motor cortex. • Absence of PGC-1α causes attenuation of GABA release upon…”
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A Role for PGC-1α in Transcription and Excitability of Neocortical and Hippocampal Excitatory Neurons
Published in Neuroscience (21-05-2020)“…•Loss of PGC-1α in PNs enhances glutamatergic transmission in the neocortex and hippocampus.•Deletion of PGC-1α from pyramidal neurons (PNs) caused ambulatory…”
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Calcium-Permeable Presynaptic Kainate Receptors Involved in Excitatory Short-Term Facilitation Onto Somatostatin Interneurons During Natural Stimulus Patterns
Published in Journal of neurophysiology (01-02-2009)“…Department of Neurobiology, Civitan International Research Center, and Evelyn F. McKnight Brain Institute, University of Alabama, Birmingham, Alabama Submitted…”
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12
LSO:Ce Inorganic Scintillators Are Biocompatible With Neuronal and Circuit Function
Published in Frontiers in synaptic neuroscience (03-09-2019)“…Optogenetics is widely used in neuroscience to control neural circuits. However, non-invasive methods for light delivery in brain are needed to avoid physical…”
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13
Neuropsychiatric Phenotypes Produced by GABA Reduction in Mouse Cortex and Hippocampus
Published in Neuropsychopharmacology (New York, N.Y.) (06-12-2017)Get full text
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Bicuculline restores frequency-dependent hippocampal I/E ratio and circuit function in PGC-1ɑ null mice
Published in Neuroscience research (01-11-2022)“…Altered inhibition/excitation (I/E) balance contributes to various brain disorders. Dysfunctional GABAergic interneurons enhance or reduce inhibition,…”
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Short-term plasticity regulates the excitation/inhibition ratio and the temporal window for spike integration in CA1 pyramidal cells
Published in The European journal of neuroscience (01-06-2015)“…Many neurodevelopmental and neuropsychiatric disorders involve an imbalance between excitation and inhibition caused by synaptic alterations. The proper…”
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16
Career Exploration: A Multivariate Analysis of Predictors
Published in Journal of vocational behavior (01-02-2000)“…This study examined the multivariate relations between career exploration and its predictors in a sample of 156 female and 162 male college students. Combining…”
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Target-cell-specific Short-term Plasticity Reduces the Excitatory Drive onto CA1 Interneurons Relative to Pyramidal Cells During Physiologically-derived Spike Trains
Published in Neuroscience (15-09-2018)“…•Short-term plasticity is target-cell specific during physiologically derived spike trains.•Target-cell-specific short-term plasticity expresses different…”
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Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control
Published in Journal of controlled release (10-08-2020)“…There is an ongoing need for noninvasive tools to manipulate brain activity with molecular, spatial and temporal specificity. Here we have investigated the use…”
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Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus
Published in The Journal of neuroscience (18-11-2015)“…Circuit dysfunction in complex brain disorders such as schizophrenia and autism is caused by imbalances between inhibitory and excitatory synaptic transmission…”
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Neuropsychiatric Phenotypes Produced by GABA Reduction in Mouse Cortex and Hippocampus
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2018)“…Whereas cortical GAD67 reduction and subsequent GABA level decrease are consistently observed in schizophrenia and depression, it remains unclear how these…”
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