Search Results - "Bartlett, Daniel"
-
1
Replication timing maintains the global epigenetic state in human cells
Published in Science (American Association for the Advancement of Science) (23-04-2021)“…The temporal order of DNA replication [replication timing (RT)] is correlated with chromatin modifications and three-dimensional genome architecture; however,…”
Get full text
Journal Article -
2
High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq)
Published in The Journal of cell biology (06-12-2021)“…Chromatin profiling in single cells has been extremely challenging and almost exclusively limited to histone proteins. In cases where single-cell methods have…”
Get full text
Journal Article -
3
The Tiger Rattlesnake genome reveals a complex genotype underlying a simple venom phenotype
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2021)“…Variation in gene regulation is ubiquitous, yet identifying the mechanisms producing such variation, especially for complex traits, is challenging. Snake…”
Get full text
Journal Article -
4
Sensitive electrochemiluminescence (ECL) immunoassays for detecting lipoarabinomannan (LAM) and ESAT-6 in urine and serum from tuberculosis patients
Published in PloS one (18-04-2019)“…Tuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to determine…”
Get full text
Journal Article -
5
The genetic regulatory architecture and epigenomic basis for age-related changes in rattlesnake venom
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-2024)“…Developmental phenotypic changes can evolve under selection imposed by age- and size-related ecological differences. Many of these changes occur through…”
Get full text
Journal Article -
6
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD
Published in Nature communications (19-05-2022)“…GGGGCC repeat expansion in C9ORF72 , which can be translated in both sense and antisense directions into five dipeptide repeat (DPR) proteins, including…”
Get full text
Journal Article -
7
Bacterial artificial chromosomes establish replication timing and sub-nuclear compartment de novo as extra-chromosomal vectors
Published in Nucleic acids research (28-02-2018)“…Abstract The role of DNA sequence in determining replication timing (RT) and chromatin higher order organization remains elusive. To address this question, we…”
Get full text
Journal Article -
8
Mapping Replication Timing in Single Mammalian Cells
Published in Current protocols (01-01-2022)“…Replication timing (RT) is the temporal order in which genomic DNA is replicated during S phase. Early and late replication correlate with transcriptionally…”
Get more information
Journal Article -
9
The time to perform spinal or general anaesthesia in COVID-19 positive parturients requiring emergency caesarean delivery: a prospective crossover simulation study
Published in Clinical and experimental obstetrics & gynecology (15-10-2021)“…Background: Spinal anaesthesia is the commonest performed technique for caesarean deliveries except in the emergency setting where general anaesthesia is…”
Get full text
Journal Article -
10
Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication
Published in Cell (07-02-2019)“…The temporal order of DNA replication (replication timing [RT]) is highly coupled with genome architecture, but cis-elements regulating either remain elusive…”
Get full text
Journal Article -
11
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment
Published in Stem cell reports (09-07-2019)“…The temporal order of DNA replication is regulated during development and is highly correlated with gene expression, histone modifications and 3D genome…”
Get full text
Journal Article -
12
The 4D nucleome project
Published in Nature (London) (14-09-2017)“…The 4D Nucleome Network aims to develop and apply approaches to map the structure and dynamics of the human and mouse genomes in space and time with the goal…”
Get full text
Journal Article -
13
Primary care management of postoperative shoulder, hip, and knee arthroplasty
Published in BMJ (Online) (18-10-2017)Get full text
Journal Article -
14
QUOKKA, the pinhole small‐angle neutron scattering instrument at the OPAL Research Reactor, Australia: design, performance, operation and scientific highlights
Published in Journal of applied crystallography (01-04-2018)“…QUOKKA is a 40 m pinhole small‐angle neutron scattering instrument in routine user operation at the OPAL research reactor at the Australian Nuclear Science and…”
Get full text
Journal Article -
15
Reducing ethnic disparity in access to high‐quality HLA‐matched cord blood units for transplantation: analysis of the Canadian Blood Services' Cord Blood Bank inventory
Published in Transfusion (Philadelphia, Pa.) (01-07-2019)“…BACKGROUND Launched in 2013, Canadian Blood Services' Cord Blood Bank (CBS' CBB) has built a high‐quality, ethnically diverse cord blood repository that aims…”
Get full text
Journal Article -
16
Profiling the Mammalian Epigenome at Single-Cell Resolution
Published 01-01-2022“…Chromatin profiling in single cells has been extremely challenging and almost exclusively limited to histone protein modifications. In cases where single cell…”
Get full text
Dissertation -
17
THE SEAL HAS BEEN LIFTED: NCAA AND PREDOMINANTLY WHITE COLLEGES MUST SOON STOP EXPLOITING THEIR BLACK ATHLETES
Published in American University business law review (01-01-2022)“…Introduced in the 117th Congress's second session, the Amateur Athletes Protection and Compensation Rights Act of 2021 ("AAPCA"), and similar legislation, aim…”
Get full text
Journal Article -
18
Sensitive electrochemiluminescence and ESAT-6 in urine and serum from tuberculosis patients
Published in PloS one (18-04-2019)“…Background Tuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to…”
Get full text
Journal Article -
19
Sensitive electrochemiluminescence
Published in PloS one (18-04-2019)“…Background Tuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to…”
Get full text
Journal Article -
20
Comparison of Ex Utero and In Utero Cord Blood Collection Methods: Canadian Blood Services’ Cord Blood Bank
Published in Stem cells translational medicine (01-09-2018)Get full text
Journal Article