Search Results - "Bartik, Mary M"

l-Canavanine modulates cellular growth, chemosensitivity and P-glycoprotein substrate accumulation in cultured human tumor cell lines by Worthen, David R, Chien, Lynn, Tsuboi, Clifford P, Mu, Xi Y, Bartik, Mary M, Crooks, Peter A

“…l-Canavanine (L-CAV) is a naturally occurring l-arginine analog that induces the formation of non-functional proteins in a variety of organisms. Previous…”
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Activation of human peripheral blood T cells does not lead to increased P-glycoprotein expression by MU, X. Y, GOSLAND, M. P, BARTIK, M. M, SCHIMMELPFENNIG, J, KAY, N. E

“…The expression of P-glycoprotein (Pgp) on normal human lymphocytes, and its drug exclusion capacity, implies that Pgp might be involved in cytokine secretion…”
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Interleukin 2 requirement for the in vitro generation of antitumor cytotoxicity by thymocytes from melphalan-cured MOPC-315 tumor bearers by Mokyr, M B, Bartik, M M, Ahn, M C

“…We have previously shown that enhanced antitumor cytotoxicity is generated when thymocytes from melphalan (L-phenylalanine mustard; L-PAM)-treated MOPC-315…”
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Melphalan-induced enhancement of antitumor immune reactivity in thymocytes of adult BALB/c mice bearing a large MOPC-315 tumor by BARTIK, M. M, TAKESUE, B. Y, MOKYR, M. B

“…At no stage of tumor growth are thymocytes from MOPC-315 tumor bearers capable of bringing about the generation of enhanced antitumor cytotoxicity when added…”
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Modulation of T cell proliferation by stimulation of the beta-adrenergic receptor: lack of correlation between inhibition of T cell proliferation and cAMP accumulation by Bartik, M M, Brooks, W H, Roszman, T L

“…The presence of beta-adrenergic receptors on T cells suggests the potential for modulating T cell function upon binding of an appropriate agonist. Utilizing…”
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Induction of cAMP-dependent protein kinase (PKA) activity in T cells after stimulation of the prostaglandin E2 or the beta-adrenergic receptors: relationship between PKA activity and inhibition of anti-CD3 monoclonal antibody-induced T cell proliferation by Bauman, G P, Bartik, M M, Brooks, W H, Roszman, T L

“…Recently, we have shown that T cells exposed to concentrations of prostaglandin E2 (PGE2) or the beta-adrenergic receptor agonist isoproterenol (ISO) that…”
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Costimulatory signals modulate the antiproliferative effects of agents that elevate cAMP in T cells by Bartik, M M, Bauman, G P, Brooks, W H, Roszman, T L

“…Stimulation of highly purified human T cells with immobilized anti-CD3 monoclonal antibody (mAb) in the presence of cAMP-inducing agents results in inhibition…”
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cAMP accumulation in T-cells inhibits anti-CD3 monoclonal antibody-induced actin polymerization by Selliah, Nithianandan, Bartik, Mary M., Carlson, Sonia L., Brooks, William H., Roszman, Thomas L.

“…The results presented in this report offer a novel explanation for how stimulation of the beta-adrenergic receptor (βAR) inhibits the ability of T cells to…”
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Enhanced expansion of the thymic CD8+ cell subset as a potential mechanism for the generation of enhanced antitumor cytotoxicity by thymocytes from low-dose melphalan-treated MOPC-315 tumor bearers by Bartik, M M, Baumgartel-Scofield, B A, Mokyr, M B

“…We have previously shown that thymocytes from low-dose melphalan (L-phenylalanine mustard)-treated MOPC-315-tumor-bearing mice (melphalan TuB) are able to…”
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Presence of an enlarged pool of MOPC-315-specific cytotoxic T lymphocyte precursors in the thymuses of mice that eradicated a large MOPC-315 tumor as a consequence of low-dose melphalan therapy by Bartik, M M, Ahn, M C, Baumgartel, B A, Hendricks, R L, Mokyr, M B

“…We have previously shown that, as a consequence of low-dose melphalan (L-phenylalanine mustard) treatment, thymocytes from mice bearing a large, day-10…”
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Melphalan-induced appearance of potent antitumor immune reactivity in tumor bearer lymphocytes co-expressing the Lyt 2 and the L3T4 antigens by Takesue, B Y, Bartik, M M, Mokyr, M B

“…We have previously shown that Sephadex G-10-adherent spleen cells from mice bearing a large MOPC-315 tumor can suppress the in vitro generation of a primary…”
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