Search Results - "Barthel, R."

HESS Opinions "Integration of groundwater and surface water research: an interdisciplinary problem?" by Barthel, R

“…Today there is a great consensus that water resource research needs to become more holistic, integrating perspectives of a large variety of disciplines…”
Get full text

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth by Kleffel, Sonja, Posch, Christian, Barthel, Steven R., Mueller, Hansgeorg, Schlapbach, Christoph, Guenova, Emmanuella, Elco, Christopher P., Lee, Nayoung, Juneja, Vikram R., Zhan, Qian, Lian, Christine G., Thomi, Rahel, Hoetzenecker, Wolfram, Cozzio, Antonio, Dummer, Reinhard, Mihm, Martin C., Flaherty, Keith T., Frank, Markus H., Murphy, George F., Sharpe, Arlene H., Kupper, Thomas S., Schatton, Tobias

“…Therapeutic antibodies targeting programmed cell death 1 (PD-1) activate tumor-specific immunity and have shown remarkable efficacy in the treatment of…”
Get full text

Increasing rates of obesity among HIV-infected persons during the HIV epidemic by Crum-Cianflone, Nancy, Roediger, Mollie Poehlman, Eberly, Lynn, Headd, Maryam, Marconi, Vincent, Ganesan, Anuradha, Weintrob, Amy, Barthel, R Vincent, Fraser, Susan, Agan, Brian K

“…The prevalence and factors associated with overweight/obesity among human immunodeficiency virus (HIV)-infected persons are unknown. We evaluated prospective…”
Get full text

Data‐Driven Estimation of Groundwater Level Time‐Series at Unmonitored Sites Using Comparative Regional Analysis by Haaf, E., Giese, M., Reimann, T., Barthel, R.

“…A new method is presented to efficiently estimate daily groundwater level time series at unmonitored sites by linking groundwater dynamics to local…”
Get full text

Index‐Based Characterization and Quantification of Groundwater Dynamics by Heudorfer, B., Haaf, E., Stahl, K., Barthel, R.

“…Time series of groundwater head measurements serve as a primary source of information on groundwater systems. In different groundwater systems, and across…”
Get full text

Trends in the incidence of cancers among HIV-infected persons and the impact of antiretroviral therapy : a 20-year cohort study by CRUM-CIANFLONE, Nancy, HUPPLER HULLSIEK, Katherine, MARCONI, Vincent, WEINTROB, Amy, GANESAN, Anuradha, BARTHEL, R. Vincent, FRASER, Susan, AGAN, Brian K, WEGNER, Scott

“…To describe trends in incidence rates of AIDS-defining cancers (ADCs) and non-AIDS-defining cancers (NADCs) during the HIV epidemic and to evaluate predictors,…”
Get full text

Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma by Barthel, Steven R., Johansson, Mats W., McNamee, Dawn M., Mosher, Deane F.

“…Eosinophilic inflammation is a characteristic feature of asthma. Integrins are highly versatile cellular receptors that regulate extravasation of eosinophils…”
Get full text

Type I interferon signaling induces melanoma cell-intrinsic PD-1 and its inhibition antagonizes immune checkpoint blockade by Holzgruber, Julia, Martins, Christina, Kulcsar, Zsofi, Duplaine, Alexandra, Rasbach, Erik, Migayron, Laure, Singh, Praveen, Statham, Edith, Landsberg, Jennifer, Boniface, Katia, Seneschal, Julien, Hoetzenecker, Wolfram, Berdan, Emma L., Ho Sui, Shannan, Ramsey, Matthew R., Barthel, Steven R., Schatton, Tobias

“…Programmed cell death 1 (PD-1) is a premier cancer drug target for immune checkpoint blockade (ICB). Because PD-1 receptor inhibition activates tumor-specific…”
Get full text

Targeting selectins and selectin ligands in inflammation and cancer by Barthel, Steven R, Gavino, Jacyln D, Descheny, Leyla, Dimitroff, Charles J

“…Inflammation and cancer metastasis are associated with extravasation of leukocytes or tumor cells from blood into tissue. Such movement is believed to follow a…”
Get more information

Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function by Grant, Christa N, Mojica, Salvador Garcia, Sala, Frederic G, Hill, J Ryan, Levin, Daniel E, Speer, Allison L, Barthel, Erik R, Shimada, Hiroyuki, Zachos, Nicholas C, Grikscheit, Tracy C

“…Short bowel syndrome (SBS) is a devastating condition in which insufficient small intestinal surface area results in malnutrition and dependence on intravenous…”
Get more information

Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells by Martins, Christina, Silva, Mariana, Rasbach, Erik, Singh, Praveen, Itoh, Yuta, Williams, Jason B., Statham, Edith, Meurer, Anna, Martinez, Daniela V., Brandenburg, Anne, Heppt, Markus V., Barthel, Steven R., Schatton, Tobias

“…Monoclonal antibodies (abs) targeting the programmed cell death 1 (PD-1) immune checkpoint pathway have revolutionized tumor therapy. Because T-cell-directed…”
Get full text

Anal cancers among HIV-infected persons: HAART is not slowing rising incidence by CRUM-CIANFLONE, Nancy F, HUPPLER HULLSIEK, Katherine, MARCONI, Vincent C, GANESAN, Anuradha, WEINTROB, Amy, BARTHEL, Robert V, AGAN, Brian K

“…To evaluate the incidence rates of anal cancer over the HIV epidemic and assess the impact of HAART use on anal cancer events. We evaluated the incidence of…”
Get full text

Homing in on the Sweet Side of Immune Checkpoint Biology by Barthel, Steven R., Schatton, Tobias

“…P-selectin glycoprotein ligand-1 (PSGL-1) and its glycostructural determinants facilitate responses to infection and cancer by promoting immune effector-cell…”
Get full text

Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking by Barthel, Steven R, Wiese, Georg K, Cho, Jaehyung, Opperman, Matthew J, Hays, Danielle L, Siddiqui, Javed, Pienta, Kenneth J, Furie, Bruce, Dimitroff, Charles J

“…How cancer cells bind to vascular surfaces and extravasate into target organs is an underappreciated, yet essential step in metastasis. We postulate that the…”
Get full text

A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse by Sala, Frédéric G, Matthews, Jamil A, Speer, Allison L, Torashima, Yasuhiro, Barthel, Erik R, Grikscheit, Tracy C

“…Tissue-engineered small intestine (TESI) has successfully been used to rescue Lewis rats after massive small bowel resection. In this study, we transitioned…”
Get more information

Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans by Giovannone, Nicholas, Antonopoulos, Aristotelis, Liang, Jennifer, Geddes Sweeney, Jenna, Kudelka, Matthew R, King, Sandra L, Lee, Gi Soo, Cummings, Richard D, Dell, Anne, Barthel, Steven R, Widlund, Hans R, Haslam, Stuart M, Dimitroff, Charles J

“…Germinal centers (GC) are microanatomical niches where B cells proliferate, undergo antibody affinity maturation, and differentiate to long-lived memory B…”
Get full text

Hepatitis B vaccination and risk of hepatitis B infection in HIV-infected individuals by LANDRUM, Michael L, HUPPLER HULLSIEK, Katherine, DOLAN, Matthew J, AGAN, Brian K, GANESAN, Anuradha, WEINTROB, Amy C, CRUM-CIANFLONE, Nancy F, VINCENT BARTHEL, R, O'CONNELL, Robert J, FIEBERG, Ann, CHUN, Helen M, MARCONI, Vincent C

“…To assess the association of hepatitis B virus (HBV) vaccination with risk of HBV infection among HIV-infected patients and HBV infection risk factors among…”
Get full text

Human fucosyltransferase 6 enables prostate cancer metastasis to bone by Li, J, Guillebon, A D, Hsu, J-w, Barthel, S R, Dimitroff, C J, Lee, Y-F, King, M R

“…Background: The interaction between human prostate cancer (PCa) cells and bone marrow (BM) endothelium follows a rolling-and-adhesion cascade mediated by…”
Get full text

Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism by Cambien, B, Karimdjee, B F, Richard-Fiardo, P, Bziouech, H, Barthel, R, Millet, M A, Martini, V, Birnbaum, D, Scoazec, J Y, Abello, J, Saati, T Al, Johnson, M G, Sullivan, T J, Medina, J C, Collins, T L, Schmid-Alliana, A, Schmid-Antomarchi, H

“…Liver and lung metastases are the predominant cause of colorectal cancer (CRC)-related mortality. Recent research has indicated that CXCR3/chemokines…”
Get full text

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy by Sackstein, Robert, Schatton, Tobias, Barthel, Steven R

“…Advances in cancer immunotherapy have offered new hope for patients with metastatic disease. This unfolding success story has been exemplified by a growing…”
Get full text