Search Results - "Barth, Thomas FE"

Establishing and evaluation of a polymerase chain reaction for the detection of Echinococcus multilocularis in human tissue by Grimm, Johannes, Krickl, Julian, Beck, Annika, Nell, Juliane, Bergmann, Monika, Tappe, Dennis, Grüner, Beate, Barth, Thomas Fe, Brehm, Klaus

“…Alveolar echinococcosis (AE) is caused by metacestode larva of the tapeworm Echinococcus multilocularis. AE diagnostics currently rely on imaging techniques…”
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Proposal of an ultrasonographic classification for hepatic alveolar echinococcosis: Echinococcosis multilocularis Ulm classification-ultrasound by Kratzer, Wolfgang, Gruener, Beate, Kaltenbach, Tanja E M, Ansari-Bitzenberger, Sarina, Kern, Peter, Fuchs, Michael, Mason, Richard A, Barth, Thomas F E, Haenle, Mark M, Hillenbrand, Andreas, Oeztuerk, Suemeyra, Graeter, Tilmann

“…AIM: To establish an ultrasonographic classification based on a large sample of patients with confirmed hepatic alveolar echinococcosis(AE).METHODS: Clinical…”
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Pancreatic cancer-derived organoids – a disease modeling tool to predict drug response by Frappart, Pierre-Olivier, Walter, Karolin, Gout, Johann, Beutel, Alica K, Morawe, Mareen, Arnold, Frank, Breunig, Markus, Barth, Thomas FE, Marienfeld, Ralf, Schulte, Lucas, Ettrich, Thomas, Hackert, Thilo, Svinarenko, Michael, Rösler, Reinhild, Wiese, Sebastian, Wiese, Heike, Perkhofer, Lukas, Müller, Martin, Lechel, André, Sainz, Bruno, Hermann, Patrick C, Seufferlein, Thomas, Kleger, Alexander

“…Background Organotypic cultures derived from pancreatic ductal adenocarcinoma (PDAC) termed pancreatic ductal cancer organoids (PDOs) recapitulate the primary…”
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Cyclin H expression is increased in GIST with very-high risk of malignancy by Dorn, Julian, Spatz, Hanno, Schmieder, Michael, Barth, Thomas Fe, Blatz, Annette, Henne-Bruns, Doris, Knippschild, Uwe, Kramer, Klaus

“…Risk estimation of gastrointestinal stromal tumours (GIST) is based on tumour size and mitotic rate according to the National Institutes of Health consensus…”
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Combining Computed Tomography and Histology Leads to an Evolutionary Concept of Hepatic Alveolar Echinococcosis by Grimm, Johannes, Beck, Annika, Nell, Juliane, Schmidberger, Julian, Hillenbrand, Andreas, Beer, Ambros J., Dezsényi, Balázs, Shi, Rong, Beer, Meinrad, Kern, Peter, Henne-Bruns, Doris, Kratzer, Wolfgang, Moller, Peter, Barth, Thomas FE, Gruener, Beate, Graeter, Tilmann

“…Alveolar echinococcosis (AE) is caused by the intermediate stage of Echinococcus multilocularis. We aimed to correlate computed tomography (CT) data with…”
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Mediastinal (thymic) large B-cell lymphoma: where do we stand? by Barth, Thomas F E, Leithäuser, Frank, Joos, Stefan, Bentz, Martin, Möller, Peter

“…Mediastinal (thymic) B-cell lymphoma (MBL) is a locally highly aggressive tumour that was first definitively described in the early 1980s. The incidence of MBL…”
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Epigenetic lockdown of CDKN1A (p21) and CDKN2A (p16) characterises the neoplastic spindle cell component of giant cell tumours of bone by Giesche, Julian, Mellert, Kevin, Geißler, Sven, Arndt, Sophia, Seeling, Carolin, Baer, Alexandra, Schultheiss, Markus, Marienfeld, Ralf, Möller, Peter, Barth, Thomas FE

“…Giant cell tumour of bone (GCTB) comprises the eponymous osteoclastic multinucleated giant cells eliciting bone lysis, an H3F3A‐mutated neoplastic…”
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Preclinical Characterization of Novel Chordoma Cell Systems and Their Targeting by Pharmocological Inhibitors of the CDK4/6 Cell-Cycle Pathway by von Witzleben, Adrian, Goerttler, Lukas T, Marienfeld, Ralf, Barth, Holger, Lechel, André, Mellert, Kevin, Böhm, Michael, Kornmann, Marko, Mayer-Steinacker, Regine, von Baer, Alexandra, Schultheiss, Markus, Flanagan, Adrienne M, Möller, Peter, Brüderlein, Silke, Barth, Thomas F E

“…Chordomas are tumors that arise at vertebral bodies and the base of the skull. Although rare in incidence, they are deadly owing to slow growth and a lack of…”
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European Haplotype of Echinococcus multilocularis in the United States by Polish, Louis B., O’Connell, Elise M., Barth, Thomas F.E., Gottstein, Bruno, Zajac, Anne, Gibson, Pamela C., Bah, Aissatou, Kirchgessner, Megan, Estrada, Marko, Seguin, M. Alexis, Ramirez-Barrios, Roger

“…This report describes the identification of a more virulent European haplotype of Echinococcus multilocularis in both humans and animals (foxes) in the United…”
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DNA methylation‐associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis by Krüger, Jana, Fischer, Anja, Breunig, Markus, Allgöwer, Chantal, Schulte, Lucas, Merkle, Jessica, Mulaw, Medhanie A, Okeke, Nnamdi, Melzer, Michael K, Morgenstern, Clara, Azoitei, Ninel, Seufferlein, Thomas, Barth, Thomas FE, Siebert, Reiner, Hohwieler, Meike, Kleger, Alexander

“…Within the pancreas, Keratin 19 (KRT19) labels the ductal lineage and is a determinant of pancreatic ductal adenocarcinoma (PDAC). To investigate KRT19…”
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A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling by Hummel, Michael, Bentink, Stefan, Berger, Hilmar, Klapper, Wolfram, Wessendorf, Swen, Barth, Thomas F.E, Bernd, Heinz-Wolfram, Cogliatti, Sergio B, Dierlamm, Judith, Feller, Alfred C, Hansmann, Martin-Leo, Haralambieva, Eugenia, Harder, Lana, Hasenclever, Dirk, Kühn, Michael, Lenze, Dido, Lichter, Peter, Martin-Subero, Jose Ignacio, Möller, Peter, Müller-Hermelink, Hans-Konrad, Ott, German, Parwaresch, Reza M, Pott, Christiane, Rosenwald, Andreas, Rosolowski, Maciej, Schwaenen, Carsten, Stürzenhofecker, Benjamin, Szczepanowski, Monika, Trautmann, Heiko, Wacker, Hans-Heinrich, Spang, Rainer, Loeffler, Markus, Trümper, Lorenz, Stein, Harald, Siebert, Reiner

“…Analysis of gene-expression patterns led to the development of a molecular definition of Burkitt's lymphoma that distinguishes it from other types of mature…”
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Prevalence and Prognostic Implications of PD-L1 Expression in Soft Tissue Sarcomas by Kelany, Mohamed, Barth, Thomas Fe, Salem, Dina, Shakweer, Marwa M

“…PD-L1 expression differs from 19 to 92% in various cancer subtypes. Its expression carries a worse prognostic value in various malignancies and could also be…”
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Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL by Ott, German, Ziepert, Marita, Klapper, Wolfram, Horn, Heike, Szczepanowski, Monika, Bernd, Heinz-Wolfram, Thorns, Christoph, Feller, Alfred C., Lenze, Dido, Hummel, Michael, Stein, Harald, Müller-Hermelink, Hans-Konrad, Frank, Matthias, Hansmann, Martin-Leo, Barth, Thomas F.E., Möller, Peter, Cogliatti, Sergio, Pfreundschuh, Michael, Schmitz, Norbert, Trümper, Lorenz, Loeffler, Markus, Rosenwald, Andreas

“…The survival of diffuse large B-cell lymphoma patients varies considerably, reflecting the molecular diversity of tumors. In view of the controversy whether…”
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Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure by Armacki, Milena, Trugenberger, Anna Katharina, Ellwanger, Ann K, Eiseler, Tim, Schwerdt, Christiane, Bettac, Lucas, Langgartner, Dominik, Azoitei, Ninel, Halbgebauer, Rebecca, Groß, Rüdiger, Barth, Tabea, Lechel, André, Walter, Benjamin M, Kraus, Johann M, Wiegreffe, Christoph, Grimm, Johannes, Scheffold, Annika, Schneider, Marlon R, Peuker, Kenneth, Zeißig, Sebastian, Britsch, Stefan, Rose-John, Stefan, Vettorazzi, Sabine, Wolf, Eckhart, Tannapfel, Andrea, Steinestel, Konrad, Reber, Stefan O, Walther, Paul, Kestler, Hans A, Radermacher, Peter, Barth, Thomas Fe, Huber-Lang, Markus, Kleger, Alexander, Seufferlein, Thomas

“…Dysregulated intestinal epithelial apoptosis initiates gut injury, alters the intestinal barrier, and can facilitate bacterial translocation leading to a…”
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Comparison of superb microvascular imaging (SMI) quantified with ImageJ to quantified contrast-enhanced ultrasound (qCEUS) in liver metastases-a pilot study by Kratzer, Wolfgang, Güthle, Melanie, Dobler, Felix, Seufferlein, Thomas, Graeter, Tilmann, Schmidberger, Julian, Barth, Thomas Fe, Klaus, Jochen

“…The aim of the study was to compare methods for the assessment of vascularisation of liver metastases (LM) between superb microvascular imaging (SMI),…”
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In chordoma, metastasis, recurrences, Ki-67 index, and a matrix-poor phenotype are associated with patients’ shorter overall survival by von Witzleben, Adrian, Goerttler, Lukas T., Lennerz, Jochen, Weissinger, Stephanie, Kornmann, Marko, Mayer-Steinacker, Regine, von Baer, Alexandra, Schultheiss, Markus, Möller, Peter, Barth, Thomas F. E.

“…Purpose To establish a chordoma tissue cohort ( n  = 43) and to correlate localization, size, metastasis, residual disease (R-status), recurrences,…”
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Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help by Hagn, Magdalena, Sontheimer, Kai, Dahlke, Karen, Brueggemann, Sabine, Kaltenmeier, Christof, Beyer, Thamara, Hofmann, Stefanie, Lunov, Oleg, Barth, Thomas FE, Fabricius, Dorit, Tron, Kyrylo, Nienhaus, Gerd Ulrich, Simmet, Thomas, Schrezenmeier, Hubert, Jahrsdörfer, Bernd

“…Recently, CD4+ T helper cells were shown to induce differentiation of human B cells into plasma cells by expressing interleukin (IL‐)21 and CD40 ligand…”
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YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Rbpj Deletion by Tharehalli, Umesh, Svinarenko, Michael, Kraus, Johann M, Kühlwein, Silke D, Szekely, Robin, Kiesle, Ute, Scheffold, Annika, Barth, Thomas F E, Kleger, Alexander, Schirmbeck, Reinhold, Kestler, Hans A, Seufferlein, Thomas, Oswald, Franz, Katz, Sarah-Fee, Lechel, André

“…Liver cholestasis is a chronic liver disease and a major health problem worldwide. Cholestasis is characterised by a decrease in bile flow due to impaired…”
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Phase II trial evaluating the efficacy and safety of the anti-CD20 monoclonal antibody obinutuzumab in patients with marginal zone lymphoma by Grunenberg, Alexander, Kaiser, Lisa M, Woelfle, Stephanie, Schmelzle, Birgit, Viardot, Andreas, Möller, Peter, Barth, Thomas Fe, Muche, Rainer, Dreyhaupt, Jens, Buske, Christian

“…Marginal zone lymphoma (MZL) belongs to the group of indolent B-cell non-Hodgkin’s lymphomas, which is characterized by an indolent course. In this mostly…”
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Drug-induced liver injury associated with the biosimilar glatiramer acetate (Clift®) by Michels, Sebastian, Zizer, Eugen, Barth, Thomas FE, Wassner, Anette, Fangerau, Tanja, Taranu, Daniela, Bachhuber, Franziska, Tumani, Hayrettin, Senel, Makbule

“…•Glatiramer acetate is a well-known drug in the long-term treatment of MS.•After the administration of Clift, an increase in liver enzymes was…”
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