Search Results - "Barth, Afonso"
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Can clinical microbiology laboratories rely on disk diffusion for accurate susceptibility assessment of cefiderocol?
Published in International journal of antimicrobial agents (01-11-2024)Get full text
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Metabolic Reprogramming of Klebsiella pneumoniae Exposed to Serum and Its Potential Implications in Host Immune System Evasion and Resistance
Published in Journal of proteome research (01-11-2024)“…The aim of this study was to identify, using proteomics, the molecular alterations caused by human serum exposure to Klebsiella pneumoniae ACH2. The analysis…”
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Detection of Carbapenem Resistance in Enterobacterales Directly From Positive Blood Cultures Using Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry
Published in Archives of pathology & laboratory medicine (1976) (01-10-2024)“…Carbapenem-resistant Enterobacterales are disseminated worldwide and associated with infections with high rates of morbidity and mortality. Matrix-assisted…”
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First identification of SARS-CoV-2 lambda (C.37) variant in Southern Brazil
Published in Infection control and hospital epidemiology (01-12-2022)“…[...]the lambda variant displays a novel deletion and multiple nonsynonymous mutations in the spike gene (Δ246-252, G75V, T76I, L452Q, F490S, D614G, and…”
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Acquisition of the mcr-1 gene by a high-risk clone of KPC-2-producing Klebsiella pneumoniae ST437/CC258, Brazil
Published in Diagnostic microbiology and infectious disease (01-02-2018)“…We identified one clinical isolate of K. pneumoniae harboring the mcr 1 (plasmid of IncX4 family) and blaKPC-2 (plasmid of IncFIB family) genes in southern…”
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Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil
Published in Euro surveillance : bulletin européen sur les maladies transmissibles (25-03-2021)“…The emergence of SARS-CoV-2 P.1 lineage coincided with a surge in hospitalisations in the North region of Brazil. In the South region's Rio Grande do Sul…”
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Rapid colorimetric polymyxin B microelution directly from positive blood bottles: because patients with serious infections should not have to wait for results of culture-based methodologies
Published in European journal of clinical microbiology & infectious diseases (01-07-2024)“…Purpose To evaluate the performance of the rapid colorimetric polymyxin B microelution (RCPEm) in determining polymyxin B resistance directly from…”
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Determination of aztreonam/ceftazidime-avibactam synergism and proposal of a new methodology for the evaluation of susceptibility in vitro
Published in Diagnostic microbiology and infectious disease (01-06-2024)“…We proposed a new methodology, the microelution ATM/CZA (mATM/CZA), based on the antibiotic disc elution and the use of resazurin, for rapid (<4h)…”
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Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients
Published in Clinical infectious diseases (15-11-2008)“…Background. Although not much pharmacokinetic knowledge is available, polymyxin B is increasingly used for treatment of infections caused by gram-negative…”
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Evaluation of the ceftazidime/avibactam and meropenem susceptibility by MALDI-TOF MS directly from positive blood cultures
Published in European journal of clinical microbiology & infectious diseases (2024)“…The purpose of this study was to evaluate the MBT-ASTRA to determine susceptibility to ceftazidime/avibactam (CZA) and meropenem (MEM) of Enterobacterales…”
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Antimicrobial resistance of Salmonella from poultry meat in Brazil: results of a nationwide survey
Published in Epidemiology and infection (08-10-2021)“…The use of antimicrobials in food-producing animals can lead to increased bacterial resistance. Important information to address this problem can be provided…”
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Pooling of samples to optimize SARS-CoV-2 diagnosis by RT-qPCR: comparative analysis of two protocols
Published in European journal of clinical microbiology & infectious diseases (01-04-2021)“…This study has aimed to evaluate the use pool of samples as a strategy to optimize the diagnostic of SARS-CoV-2 by RT-qPCR. A total of 220 naso/orofaryngeal…”
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Detection of KPC enzyme by MALDI-TOF MS from bacteria impregnated in filter paper
Published in Journal of microbiological methods (01-08-2024)“…The main mechanism that causes resistance to carbapenem, one of the most potent antibiotic available, in Enterobacterales bacterial isolates, is due to…”
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Low prevalence of the mcr-1 gene among carbapenemase-producing clinical isolates of Enterobacterales
Published in Infection control and hospital epidemiology (01-02-2019)“…All 5 isolates were recovered from rectal swabs, with exception of E. coli 6699F, which was recovered from an ascites fluid. [...]4 isolates presented…”
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Detection of KPC directly from positive blood cultures by MALDI-TOF: From research to the clinical microbiology laboratory routine
Published in Journal of microbiological methods (01-06-2024)“…Bloodstream infections (BSI) caused by carbapenem-resistant Gram-negative bacilli (CR-GNB) are a subject of major clinical concern, mainly those associated…”
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Establishing a quantitative index of meropenem hydrolysis for the detection of KPC- and NDM-producing bacteria by MALDI-TOF MS
Published in Journal of microbiological methods (01-08-2021)“…Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS), commonly used for microorganism identification, can also be…”
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Comparative microbiome analysis in cystic fibrosis and non-cystic fibrosis bronchiectasis
Published in Respiratory research (18-05-2024)“…Bronchiectasis is a condition characterized by abnormal and irreversible bronchial dilation resulting from lung tissue damage and can be categorized into two…”
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Early detection of the SARS-CoV-2 P.1 variant in Rio Grande do Sul, Brazil: a case report
Published in Infection control and hospital epidemiology (01-12-2022)“…To the Editor—In December 2019, a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China and was associated with…”
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Invasive liver abscess syndrome with central nervous system involvement caused by hypermucoviscous Klebsiella pneumoniae: positive string test
Published in The Lancet (British edition) (18-05-2024)“…On examination, she was hypotensive with a blood pressure of 80/50 mm Hg; heart rate was 122 beats per min, respiratory rate was 22 breaths per min. The…”
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Increased frequency of bla NDM in a tertiary care hospital in southern Brazil
Published in Brazilian journal of microbiology (01-03-2021)“…Resistance to carbapenems due to metallo-beta-lactamase NDM-1 was first described in Brazil in 2013. To date, only a few scattered reports of the prevalence of…”
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