Search Results - "Barter, J"

Regulation of High-Density Lipoprotein Metabolism by Rye, Kerry-Anne, Barter, Philip J

“…There is compelling evidence from human population studies that plasma levels of high-density lipoprotein (HDL) cholesterol correlate inversely with…”
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Effect of Two Intensive Statin Regimens on Progression of Coronary Disease by Nicholls, Stephen J, Ballantyne, Christie M, Barter, Philip J, Chapman, M. John, Erbel, Raimund M, Libby, Peter, Raichlen, Joel S, Uno, Kiyoko, Borgman, Marilyn, Wolski, Kathy, Nissen, Steven E

“…In this trial, intravascular ultrasonography was used to compare the effects of atorvastatin versus rosuvastatin on regression of coronary atherosclerosis…”
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The function of microRNAs in cartilage and osteoarthritis by Swingler, Tracey E, Niu, Lingzi, Smith, Perry, Paddy, Paige, Le, Linh, Barter, Matthew J, Young, David A, Clark, Ian M

“…MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression and have been shown to have key roles in both chondrocyte development and…”
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Cholesteryl ester transfer protein and its inhibitors by Shrestha, Sudichhya, Wu, Ben J., Guiney, Liam, Barter, Philip J., Rye, Kerry-Anne

“…Most of the cholesterol in plasma is in an esterified form that is generated in potentially cardioprotective HDLs. Cholesteryl ester transfer protein (CETP)…”
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Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis by Rushton, Michael D., Reynard, Louise N., Barter, Matt J., Refaie, Ramsay, Rankin, Kenneth S., Young, David A., Loughlin, John

“…Objective The aim of this study was to characterize the genome‐wide DNA methylation profile of chondrocytes from knee and hip cartilage obtained from patients…”
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A VOYAGER Meta-Analysis of the Impact of Statin Therapy on Low-Density Lipoprotein Cholesterol and Triglyceride Levels in Patients With Hypertriglyceridemia by Karlson, Björn W., MD, PhD, Palmer, Michael K., PhD, Nicholls, Stephen J., MBBS, PhD, Lundman, Pia, MD, PhD, Barter, Philip J., MBBS, PhD

“…Elevated triglyceride (TG) levels are associated with increased cardiovascular disease risk. In patients with mild-to-moderate hypertriglyceridemia, defined by…”
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Effects of Torcetrapib in Patients at High Risk for Coronary Events by Barter, Philip J, Caulfield, Mark, Eriksson, Mats, Grundy, Scott M, Kastelein, John J.P, Komajda, Michel, Lopez-Sendon, Jose, Mosca, Lori, Tardif, Jean-Claude, Waters, David D, Shear, Charles L, Revkin, James H, Buhr, Kevin A, Fisher, Marian R, Tall, Alan R, Brewer, Bryan

“…Torcetrapib, a cholesteryl ester transfer protein inhibitor, markedly raises levels of high-density lipoprotein cholesterol. Unexpectedly, in the ILLUMINATE…”
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Effect of long-term dietary sphingomyelin supplementation on atherosclerosis in mice by Chung, Rosanna W S, Wang, Zeneng, Bursill, Christina A, Wu, Ben J, Barter, Philip J, Rye, Kerry-Anne

“…Sphingomyelin (SM) levels in the circulation correlate positively with atherosclerosis burden. SM is a ubiquitous component of human diets, but it is unclear…”
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Effect of statins on HDL-C: a complex process unrelated to changes in LDL-C: analysis of the VOYAGER Database by Barter, Philip J., Brandrup-Wognsen, Gunnar, Palmer, Mike K., Nicholls, Stephen J.

“…The relationship between statin-induced increases in HDL cholesterol (HDL-C) concentration and statin-induced decreases in LDL cholesterol (LDL-C) is unknown…”
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Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society Severe Familial Hypercholesterolemia Panel by Santos, Raul D, Dr, Gidding, Samuel S, Prof, Hegele, Robert A, Prof, Cuchel, Marina A, Prof, Barter, Philip J, Prof, Watts, Gerald F, Prof, Baum, Seth J, MD, Catapano, Alberico L, Prof, Chapman, M John, Prof, Defesche, Joep C, Prof, Folco, Emanuela, PhD, Freiberger, Tomas, PhD, Genest, Jacques, Prof, Hovingh, G Kees, PhD, Harada-Shiba, Mariko, PhD, Humphries, Steve E, Prof, Jackson, Ann S, MBA, Mata, Pedro, MD, Moriarty, Patrick M, Prof, Raal, Frederick J, Prof, Al-Rasadi, Khalid, MD, Ray, Kausik K, Prof, Reiner, Zelijko, Prof, Sijbrands, Eric J G, Prof, Yamashita, Shizuya, Prof

“…Summary Familial hypercholesterolaemia is common in individuals who had a myocardial infarction at a young age. As many as one in 200 people could have…”
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Effects of age, gender and statin dose on lipid levels: Results from the VOYAGER meta-analysis database by Karlson, Björn W., Palmer, Michael K., Nicholls, Stephen J., Barter, Philip J., Lundman, Pia

“…The effectiveness of statins in the treatment of dyslipidaemia and reduction of cardiovascular risk is well established. However, the association of…”
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The metabolism and anti-atherogenic properties of HDL by Rye, Kerry-Anne, Bursill, Christina A., Lambert, Gilles, Tabet, Fatiha, Barter, Philip J.

“…Population studies have shown that plasma HDL levels correlate inversely with cardiovascular disease risk. In recent years there has been intense interest in…”
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Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial by Hovingh, G Kees, Dr, Kastelein, John J P, Prof, van Deventer, Sander J H, Prof, Round, Patrick, Ford, John, Saleheen, Danish, Rader, Daniel J, Prof, Brewer, H Bryan, Prof, Barter, Philip J, Prof

“…Summary Background Dyslipidaemia remains a significant risk factor for cardiovascular disease and additional lipid-modifying treatments are warranted to…”
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Antiinflammatory Properties of HDL by Barter, Philip J, Nicholls, Stephen, Rye, Kerry-Anne, Anantharamaiah, G M, Navab, Mohamad, Fogelman, Alan M

“…There are several well-documented functions of high-density lipoprotein (HDL) that may explain the ability of these lipoproteins to protect against…”
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High-density lipoproteins: A consensus statement from the National Lipid Association by Toth, Peter P., MD, PhD, FNLA, Chair, Barter, Philip J., MD, PhD, Co-Chair, Rosenson, Robert S., MD, FNLA, Co-Chair, Boden, William E., MD, Chapman, M. John, PhD, DSc, Cuchel, Marina, MD, PhD, D'Agostino, Ralph B., PhD, Davidson, Michael H., MD, FNLA, Davidson, W. Sean, PhD, Heinecke, Jay W., MD, Karas, Richard H., MD, PhD, Kontush, Anatol, PhD, Krauss, Ronald M., MD, Miller, Michael, MD, Rader, Daniel J., MD, FNLA

“…Abstract For >4 decades it has been recognized that elevated serum levels of high-density lipoprotein cholesterol (HDL-C) are associated with reduced risk of…”
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Genome‐Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR‐140‐5p by Barter, Matt J., Tselepi, Maria, Gómez, Rodolfo, Woods, Steven, Hui, Wang, Smith, Graham R., Shanley, Daryl P., Clark, Ian M., Young, David A.

“…microRNAs (miRNAs) are abundantly expressed in development where they are critical determinants of cell differentiation and phenotype. Accordingly miRNAs are…”
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Coronary atheroma volume and cardiovascular events during maximally intensive statin therapy by Puri, Rishi, Nissen, Steven E, Shao, Mingyuan, Ballantyne, Christie M, Barter, Phillip J, Chapman, M John, Erbel, Raimund, Libby, Peter, Raichlen, Joel S, Uno, Kiyoko, Kataoka, Yu, Nicholls, Stephen J

“…The impact of baseline coronary plaque burden on the clinical outcome in patients receiving aggressive low-density lipoprotein cholesterol (LDL-C) lowering…”
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The expression and function of microRNAs in chondrogenesis and osteoarthritis by Swingler, Tracey E., Wheeler, Guy, Carmont, Virginia, Elliott, Hannah R., Barter, Matthew J., Abu-Elmagd, Muhammad, Donell, Simon T., Boot-Handford, Raymond P., Hajihosseini, Mohammad K., Münsterberg, Andrea, Dalmay, Tamas, Young, David A., Clark, Ian M.

“…Objective To use an in vitro model of chondrogenesis to identify microRNAs (miRNAs) with a functional role in cartilage homeostasis. Methods The expression of…”
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Assessment of omega‐3 carboxylic acids in statin‐treated patients with high levels of triglycerides and low levels of high‐density lipoprotein cholesterol: Rationale and design of the STRENGTH trial by Nicholls, Stephen J., Lincoff, A. Michael, Bash, Dianna, Ballantyne, Christie M., Barter, Philip J., Davidson, Michael H., Kastelein, John J. P., Koenig, Wolfgang, McGuire, Darren K., Mozaffarian, Dariush, Pedersen, Terje R., Ridker, Paul M., Ray, Kausik, Karlson, Björn W., Lundström, Torbjörn, Wolski, Kathy, Nissen, Steven E.

“…It is uncertain whether omega‐3 fatty acids are beneficial in statin‐treated patients. Epanova is a mix of omega‐3 free fatty acids, not requiring co‐ingestion…”
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Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I by Rye, Kerry-Anne, Barter, Philip J

“…ABSTRACT—The preferred extracellular acceptor of cell phospholipids and unesterified cholesterol in the process mediated by the ATP-binding cassette A1 (ABCA1)…”
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