Search Results - "Bartel, Paul L."

Chromosome 10q26–driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium by Williams, Brandi L., Seager, Nathan A., Gardiner, Jamie D., Pappas, Chris M., Cronin, Monica C., di San Filippo, Cristina Amat, Anstadt, Robert A., Liu, Jin, Toso, Marc A., Nichols, Lisa, Parnell, Timothy J., Eve, Jacqueline R., Bartel, Paul L., Zouache, Moussa A., Richards, Burt T., Hageman, Gregory S.

“…Genome-wide association studies have identified the chromosome 10q26 (Chr10) locus, which contains the age-related maculopathy susceptibility 2 (ARMS2) and…”
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Construction and characterization of a normalized yeast two-hybrid library derived from a human protein-coding clone collection by DeGrado-Warren, Jorja, Dufford, Max, Chen, Jian, Bartel, Paul L, Shattuck, Donna, Frech, Georges C

“…The nuclear yeast two-hybrid (Y2H) system is the most widely used technology for detecting interactions between proteins. A common approach is to screen…”
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Characterization of a carboxy-terminal BRCA1 interacting protein by WONG, A. K. C, ORMONDE, P. A, TAVTIGIAN, S. V, TENG, D. H.-F, BARTEL, P. L, PERO, R, YUAN CHEN, LUBING LIAN, SALADA, G, BERRY, S, LAWRENCE, Q, DAYANANTH, P, PHUONG HA

“…There are several lines of evidence indicating that the carboxy-terminal region of the tumor suppressor protein BRCA1 is a functionally significant domain…”
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A protein linkage map of Escherichia coli bacteriophage T7 by Bartel, Paul L, Roecklein, Jennifer A, SenGupta, Dhruba, Fields, Stanley

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RAD51 Interacts with the Evolutionarily Conserved BRC Motifs in the Human Breast Cancer Susceptibility Gene brca2 by Wong, Alexander K.C., Pero, Ralph, Ormonde, Patricia A., Tavtigian, Sean V., Bartel, Paul L.

“…Recent work has shown that the murine BRCA2 tumor suppressor protein interacts with the murine RAD51 protein. This interaction suggests that BRCA2 participates…”
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Two Cellular Proteins that Bind to Wild-Type but not Mutant p53 by Iwabuchi, Kuniyoshi, Bartel, Paul L., Li, Bin, Marraccino, Robert, Fields, Stanley

“…p53 is a tumor-suppressor protein that can activate and repress transcription. Using the yeast two-hybrid system, we identified two previously uncharacterized…”
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Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding by ADEY, N. B, LIWEN HUANG, ORMONDE, P. A, BAUMGARD, M. L, PERO, R, BYREDDY, D. V, TAVTIGIAN, S. V, BARREL, P. L

“…Two-hybrid searches with the tumor suppressor MMAC1/PTEN isolated the proteins hDLG and hMAST205. Further two-hybrid analysis and microtiter plate binding…”
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Analyzing protein-protein interactions using two-hybrid system by Bartel, P L, Fields, S

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The Two-Hybrid System: A Method to Identify and Clone Genes for Proteins that Interact with a Protein of Interest by Chien, Cheng-ting, Bartel, Paul L., Sternglanz, Rolf, Fields, Stanley

“…We describe a method that detects proteins capable of interacting with a known protein and that results in the immediate availability of the cloned genes for…”
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Current Protocols in Molecular Biology . Frederick M. Ausubel , Roger Brent , Robert E. Kingston , David D. Moore , J. G. Seidman , John A. Smith , Kevin Struhl Short Protocols in Molecular Biology. A Compendium of Methods from Current Protocols in Molecular Biology . Frederick M. Ausubel , Roger Brent , Robert E. Kingston , David D. Moore , J. G. Seidman , John A. Smith , Kevin Struhl by Bartel, Paul L.

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Current Protocols in Molecular Biology by Bartel, Paul L.

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Expression of polyketide biosynthesis and regulatory genes in heterologous streptomycetes by Strohl, W R, Bartel, P L, Li, Y, Connors, N C, Woodman, R H

“…There are now several examples showing that hybrid secondary metabolites can be produced as a result of interspecies cloning of antibiotic biosynthesis genes…”
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Biosynthesis of anthracydines: enzymic conversion of aklanonic acid to aklavinone and {varepsilon}-rhodomycinone by anthracycline-producing streptomycetes by Connors, Neal C, Bartel, Paul L, Strohl, William R

“…Department of Microbiology, The Ohio State University, 484 West 12th Avenue, Columbus, Ohio 43210, USA ABSTRACT Summary: Aklanonic acid, a substituted…”
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Biosynthesis of anthracyclines: carminomycin 4-O-methyltransferase, the terminal enzymic step in the formation of daunomycin by Connors, Neal C, Bartel, Paul L, Strohl, William R

“…Department of Microbiology, The Ohio State University, 484 West 12th Avenue, Columbus, Ohio 43210, USA ABSTRACT Summary: In the presence of S-adenosyl- L…”
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