Search Results - "Bartalesi, Barbara"

Smoking Cessation in Mice Does Not Switch off Persistent Lung Inflammation and Does Not Restore the Expression of HDAC2 and SIRT1 by De Cunto, Giovanna, De Meo, Simone, Bartalesi, Barbara, Cavarra, Eleonora, Lungarella, Giuseppe, Lucattelli, Monica

“…Once COPD is established, pulmonary lesions can only progress and smoking cessation by itself is not sufficient to switch off persistent lung inflammation…”
Get full text

Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung by Lucattelli, Monica, Fineschi, Silvia, Selvi, Enrico, Garcia Gonzalez, Estrella, Bartalesi, Barbara, De Cunto, Giovanna, Lorenzini, Sauro, Galeazzi, Mauro, Lungarella, Giuseppe

“…Ajulemic acid (AjA) is a synthetic analogue of tetrahydrocannabinol that can prevent and limit progression of skin fibrosis in experimental systemic sclerosis…”
Get full text

Smoking p66Shc knocked out mice develop respiratory bronchiolitis with fibrosis but not emphysema by Lunghi, Benedetta, De Cunto, Giovanna, Cavarra, Eleonora, Fineschi, Silvia, Bartalesi, Barbara, Lungarella, Giuseppe, Lucattelli, Monica

“…The adaptor protein p66Shc regulates intracellular oxidant levels through the modulation of a forkhead-related transcription factor (FOXO3a). The genetic…”
Get full text

Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia by Atzori, Luigi, Lucattelli, Monica, Scotton, Chris J, Laurent, Geoffrey J, Bartalesi, Barbara, De Cunto, Giovanna, Lunghi, Benedetta, Chambers, Rachel C, Lungarella, Giuseppe

“…The morphological features of chronic obstructive pulmonary disease in man include emphysema and chronic bronchitis associated with mucus hypersecretion. These…”
Get full text

Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models by Lucattelli, Monica, Bartalesi, Barbara, Cavarra, Eleonora, Fineschi, Silvia, Lunghi, Benedetta, Martorana, Piero A, Lungarella, Giuseppe

“…The separation of emphysema from fibrosis is not as clear-cut as it was thought in early studies. These two pathologies may be present at the same time in…”
Get full text

Histopathological data of iron and calcium in the mouse lung after asbestos exposure by Trevisan, Elisa, Zabucchi, Giuliano, Pascolo, Lorella, Pascotto, Ernesto, Casarsa, Claudia, Lucattelli, Monica, Lungarella, Giuseppe, Cavarra, Eleonora, Bartalesi, Barbara, Zweyer, Marina, Borelli, Violetta

“…This data article contains data related to the research article entitled, “Synchrotron X-ray microscopy reveals early calcium and iron interaction with…”
Get full text

Early response to bleomycin is characterized by different cytokine and cytokine receptor profiles in lungs by Cavarra, Eleonora, Carraro, Fabio, Fineschi, Silvia, Naldini, Antonella, Bartalesi, Barbara, Pucci, Annalisa, Lungarella, Giuseppe

“…The sensitivity to the fibrosis-inducing effect of bleomycin varies considerably from species to species, the reasons for which are unknown. The variability of…”
Get more information

Immunohistochemical Study of Airways Fibrous Remodeling in Smoking Mice by Balzano, Emilia, De Cunto, Giovanna, Goracci, Chiara, Bartalesi, Barbara, Cavarra, Eleonora, Lungarella, Giuseppe, Lucattelli, Monica

“…The fibrotic remodeling in chronic obstructive pulmonary disease (COPD) is held responsible for narrowing of small airways and thus for disease progression…”
Get full text

Lung ultrasound features and relationships with respiratory mechanics of evolving BPD in preterm rabbits and human neonates by Loi, Barbara, Casiraghi, Costanza, Catozzi, Chiara, Storti, Matteo, Lucattelli, Monica, Bartalesi, Barbara, Yousef, Nadya, Salomone, Fabrizio, De Luca, Daniele

“…We have reported that hyperoxia-exposed preterm rabbits and human preterm neonates with evolving BPD have the same lung ultrasound appearance, and that lung…”
Get full text

Ongoing Lung Inflammation and Disease Progression in Mice after Smoking Cessation: Beneficial Effects of Formyl-Peptide Receptor Blockade by De Cunto, Giovanna, Bartalesi, Barbara, Cavarra, Eleonora, Balzano, Emilia, Lungarella, Giuseppe, Lucattelli, Monica

“…The most important risk factor for chronic obstructive pulmonary disease (COPD) is cigarette smoking. Until now, smoking cessation (SC) is the only treatment…”
Get full text

Cellular Senescence as Fibrogenic Mechanism in Smoking Lung by Goracci, Chiara, Balzano, Emilia, De Cunto, Giovanna, Bartalesi, Barbara, Cavarra, Eleonora, Lungarella, Giuseppe, Lucattelli, Monica

“…Age is a risk factor for many diseases including idiopathic pulmonary fibrosis (IPF) by affecting wound healing through abnormal fibrogenesis. Common cellular…”
Get full text

Functional contribution of sphingosine‐1‐phosphate to airway pathology in cigarette smoke‐exposed mice by De Cunto, Giovanna, Brancaleone, Vincenzo, Riemma, Maria Antonietta, Cerqua, Ida, Vellecco, Valentina, Spaziano, Giuseppe, Cavarra, Eleonora, Bartalesi, Barbara, D'Agostino, Bruno, Lungarella, Giuseppe, Cirino, Giuseppe, Lucattelli, Monica, Roviezzo, Fiorentina

“…Background and Purpose A critical role for sphingosine kinase/sphingosine‐1‐phosphate (S1P) pathway in the control of airway function has been demonstrated in…”
Get full text

Ongoing Lung Inflammation and Disease Progression in Mice after Smoking Cessation by De Cunto, Giovanna, Bartalesi, Barbara, Cavarra, Eleonora, Balzano, Emilia, Lungarella, Giuseppe, Lucattelli, Monica

“…The most important risk factor for chronic obstructive pulmonary disease (COPD) is cigarette smoking. Until now, smoking cessation (SC) is the only treatment…”
Get full text

Severe Reduction in Number and Function of Peripheral T Cells Does Not Afford Protection toward Emphysema and Bronchial Remodeling Induced in Mice by Cigarette Smoke by De Cunto, Giovanna, Lunghi, Benedetta, Bartalesi, Barbara, Cavarra, Eleonora, Fineschi, Silvia, Ulivieri, Cristina, Lungarella, Giuseppe, Lucattelli, Monica

“…The protein Lck (p56 Lck ) is a Src family tyrosine kinase expressed at all stages of thymocyte development and is required for maturation of T cells. The…”
Get full text

Innate Immunity and Cell Surface Receptors in the Pathogenesis of COPD: Insights from Mouse Smoking Models by De Cunto, Giovanna, Cavarra, Eleonora, Bartalesi, Barbara, Lucattelli, Monica, Lungarella, Giuseppe

“…Chronic obstructive pulmonary disease (COPD) is mainly associated with smoking habit. Inflammation is the major initiating process whereby neutrophils and…”
Get full text

Synchrotron X-ray microscopy reveals early calcium and iron interaction with crocidolite fibers in the lung of exposed mice by Pascolo, Lorella, Zabucchi, Giuliano, Gianoncelli, Alessandra, Kourousias, George, Trevisan, Elisa, Pascotto, Ernesto, Casarsa, Claudia, Ryan, Chris, Lucattelli, Monica, Lungarella, Giuseppe, Cavarra, Eleonora, Bartalesi, Barbara, Zweyer, Marina, Cammisuli, Francesca, Melato, Mauro, Borelli, Violetta

“…[Display omitted] •In a murine model of asbestos exposure a relevant inflammatory and atypical hyperplastic reaction was induced.•Inflamed lung tissue regions…”
Get full text

Effects of cigarette smoke in mice with different levels of α1-Proteinase inhibitor and sensitivity to oxidants by CAVARRA, Eleonora, BARTALESI, Barbara, LUCATTELLI, Monica, FINESCHI, Silvia, LUNGHI, Benedetta, GAMBELLI, Federica, ORTIZ, Luis A, MARTORANA, Piero A, LUNGARELLA, Giuseppe

Get full text

Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress by Cavarra, E, Lucattelli, M, Gambelli, F, Bartalesi, B, Fineschi, S, Szarka, A, Giannerini, F, Martorana, P A, Lungarella, G

“…The role of oxidative stress in inactivating antiproteases is the object of debate. To address this question, we developed an in vivo model of pulmonary…”
Get more information

Effects of Cigarette Smoke in Mice with Different Levels of alpha 1-Proteinase Inhibitor and Sensitivity to Oxidants by CAVARRA, ELEONORA, BARTALESI, BARBARA, LUCATTELLI, MONICA, FINESCHI, SILVIA, LUNGHI, BENEDETTA, GAMBELLI, FEDERICA, ORTIZ, LUIS A, MARTORANA, PIERO A, LUNGARELLA, GIUSEPPE

Get full text

Neutrophil Influx into the Lungs of Beige Mice Is Followed by Elastolytic Damage and Emphysema by Cavarra, Eleonora, Martorana, Piero A, de Santi, Margherita, Bartalesi, Barbara, Cortese, Simone, Gambelli, Federica, Lungarella, Giuseppe

“…The beige mouse is currently used as a model of elastase and cathepsin G deficiency to demonstrate or exclude the role of these proteases in a variety of…”
Get full text