Search Results - "Barsotti, Giulia"
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The role of nanoliposomal irinotecan plus fluorouracil/leucovorin in the continuum of care of patients with metastatic pancreatic ductal adenocarcinoma
Published in Cancer medicine (Malden, MA) (01-07-2023)“…Background The NAPOLI‐I trial showed better outcome of nanoliposomal irinotecan (nal‐IRI) plus 5‐fluorouracil/leucovorin (5‐FU/LV) compared to 5‐FU/LV in…”
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Real-world impact of olaparib use in patients (pts) with advanced pancreatic cancer (PC) harboring germline BRCA 1/2 (g BRCA ) mutations
Published in Journal of clinical oncology (01-06-2023)“…e16278 Background: g BRCA mutations are found in approximately 8% of Italian PC pts screened within 3 months from diagnosis. g BRCA PC pts display enhanced…”
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Real-world performance and clinical outcome of comprehensive genomic profiling of gastrointestinal tumors: High-volume, single-center experience
Published in Journal of clinical oncology (20-01-2024)“…727 Background: In order to identify targetable mutations, the Comprehensive Genomic Profiling (CGP) is an important tool. Technologies like extensive genomic…”
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Negative hyperselection of elderly patients with RAS and BRAF wild-type metastatic colorectal cancer receiving initial panitumumab plus FOLFOX or 5-FU/LV
Published in European journal of cancer (1990) (01-12-2023)“…BACKGROUNDUpfront anti-EGFR therapy represents the standard of care for patients with left-sided, MSS/pMMR, RAS and BRAF wild-type mCRC. Molecular…”
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The oncological multidimensional prognostic index is a promising decision-making tool: A real-world analysis in older patients with metastatic colorectal cancer
Published in European journal of cancer (1990) (01-12-2022)“…Approximately 50% of colorectal cancers occur in older patients. International societies recommend geriatric tools to optimise treatment of older patients…”
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Pattern of recurrence and overall survival in esophagogastric cancer after perioperative FLOT and clinical outcomes in MSI-H population: the PROSECCO Study
Published in Journal of cancer research and clinical oncology (01-08-2023)“…Background FLOT regimen is the standard perioperative treatment in Western countries for patients with locally advanced gastric (GC) or gastroesophageal…”
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Understanding resistance in V600E BRAF advanced colon cancer treated with BRAF inhibitors plus anti-EGFR antibodies +/- MEK inhibitors: The URBAN study
Published in Journal of clinical oncology (01-06-2023)“…3587 Background: The combination of BRAF inhibitors (BRAFi) plus anti-EGFR antibodies is a new standard of care in V600E BRAF mutated (mut) metastatic…”
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Immunotherapy in RAS mutant mCRC: Could CTLA-4 blockade increase the efficacy of anti PD-1 agents? Preliminary clinical results of the NERDY study
Published in Journal of clinical oncology (01-02-2023)“…218 Background: Immune checkpoint inhibitors (ICI) showed high efficacy in both first and subsequent lines in metastatic colorectal cancer with mismatch repair…”
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HER2 expression and extensive molecular characterization of resected brain metastases from colorectal cancer: The HEROES study
Published in Journal of clinical oncology (01-06-2022)“…2025 Background: Brain metastases (BM) from primary colorectal cancer (prCRC) are rare (1-3%); few is known about CRC BM predictive factors, prognosticators…”
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A Real-World Application of Liquid Biopsy in Metastatic Colorectal Cancer: The Poseidon Study
Published in Cancers (13-10-2021)“…Background: First-line decision making is the key to the successful care of mCRC patients and RAS/BRAF status is crucial to select the best targeted agent. In…”
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