Search Results - "Barry, Aïssata"
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PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study
Published in The Lancet infectious diseases (01-05-2020)“…PRIMVAC is a VAR2CSA-derived placental malaria vaccine candidate aiming to prevent serious clinical outcomes of Plasmodium falciparum infection during…”
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Defining the next generation of severe malaria treatment: a target product profile
Published in Malaria journal (05-06-2024)“…Severe malaria is a life-threatening infection, particularly affecting children under the age of 5 years in Africa. Current treatment with parenteral…”
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First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children
Published in PloS one (12-12-2018)“…Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified Vaccinia Virus Ankara (MVA) vectored vaccines is a strategy…”
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Integrative genomic analysis reveals mechanisms of immune evasion in P. falciparum malaria
Published in Nature communications (09-10-2020)“…The mechanisms behind the ability of Plasmodium falciparum to evade host immune system are poorly understood and are a major roadblock in achieving malaria…”
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Understanding and maximising the community impact of seasonal malaria chemoprevention in Burkina Faso (INDIE-SMC): study protocol for a cluster randomised evaluation trial
Published in BMJ open (12-03-2024)“…IntroductionSeasonal malaria chemoprevention (SMC) involves repeated administrations of sulfadoxine-pyrimethamine plus amodiaquine to children below the age of…”
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PA-658 Shigella incidence and resistance to commonly used antibiotics in children under five years of age living in a community setting in Ouagadougou, Burkina Faso
Published in BMJ global health (17-12-2023)“…BackgroundShigellosis is a major public health problem worldwide. There is no vaccine to control shigellosis, which is the best way to control infectious…”
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Lessons learned from the use of HRP-2 based rapid diagnostic test in community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso
Published in Malaria journal (27-01-2014)“…Rapid diagnostic tests (RDTs) are immune chromatographic tests targeting antigens of one or more Plasmodium species and offer the potential to extend accurate…”
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OC 8552 EFFICACY OF THE CHAD63-MVC ME-TRAP VECTORED MALARIA VACCINE CANDIDATE IN 5–17 MONTHS OLD INFANTS AND CHILDREN IN BURKINA FASO
Published in BMJ global health (01-04-2019)“…Background Heterologous prime-boost immunisation with chimpanzee adenovirus 63 (ChAd63) and Modified Vaccinia Virus Ankara (MVA)-vectored vaccines is a…”
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Higher gametocyte production and mosquito infectivity in chronic compared to incident Plasmodium falciparum infections
Published in Nature communications (26-04-2021)“…Plasmodium falciparum gametocyte kinetics and infectivity may differ between chronic and incident infections. In the current study, we assess parasite kinetics…”
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Plasmodium falciparum Gametocyte Density and Infectivity in Peripheral Blood and Skin Tissue of Naturally Infected Parasite Carriers in Burkina Faso
Published in The Journal of infectious diseases (28-05-2021)“…Abstract Background Plasmodium falciparum transmission depends on mature gametocytes that can be ingested by mosquitoes taking a blood meal on human skin…”
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Efficacy and Safety of the Mosquitocidal Drug Ivermectin to Prevent Malaria Transmission After Treatment: A Double-Blind, Randomized, Clinical Trial
Published in Clinical infectious diseases (01-02-2015)“…Background. Artemisinin combination therapy effectively clears asexual malaria parasites and immature gametocytes but does not prevent posttreatment malaria…”
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African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker
Published in Malaria journal (10-04-2019)“…Today, the development of new and well-tolerated anti-malarial drugs is strongly justified by the emergence of Plasmodium falciparum resistance. In 2014-2015,…”
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Impact of Plasmodium falciparum infection on DNA methylation of circulating immune cells
Published in Frontiers in genetics (04-07-2023)“…The regulation of immune cell responses to infection is a complex process that involves various molecular mechanisms, including epigenetic regulation. DNA…”
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Haemolysis and haem oxygenase-1 induction during persistent "asymptomatic" malaria infection in Burkinabé children
Published in Malaria journal (06-07-2018)“…The haemolysis associated with clinical episodes of malaria results in the liberation of haem, which activates the enzyme haem oxygenase-1 (HO-1). HO-1 has…”
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Contribution of the Rapid LAMP-Based Diagnostic Test (RLDT) to the Evaluation of Enterotoxigenic Escherichia coli (ETEC) and Shigella in Childhood Diarrhea in the Peri-Urban Area of Ouagadougou, Burkina Faso
Published in Microorganisms (Basel) (01-11-2023)“…The estimates of enterotoxigenic Escherichia coli (ETEC) and Shigella burden in developing countries are limited by the lack of rapid, accessible, and…”
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ASSESSING THE COMMITMENT, MATURATION AND INFECTIVITY OF SEXUAL STAGES OF MALARIA PARASITES IN SCHOOLCHILDREN LIVING IN A HIGH MALARIA TRANSMISSION AREA OF BURKINA FASO
Published in BMJ global health (01-02-2017)“…BackgroundWith the move towards malaria elimination, it becomes essential to understand the contribution of asymptomatic parasite carriers to disease…”
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Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso
Published in Wellcome open research (01-05-2019)“…Background: Individuals living in malaria-endemic regions develop immunity against severe malaria, but it is unclear whether immunity against pre-erythrocytic…”
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Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso
Published in Wellcome open research (2018)“…Individuals living in malaria-endemic regions develop immunity against severe malaria, but it is unclear whether immunity against pre-erythrocytic stages that…”
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Profil épidémiologique et clinique des enfants atteints de la maladie à coronavirus (COVID-19) au Centre de Traitement des Epidémies et Prévention des Infections (CTEPI) du CHU de Donka à Conakry
Published in The Pan African medical journal (2020)“…La COVID-19 est due au virus SARS-CoV-2 génétiquement semblable au virus du syndrome respiratoire aigu sévère (SARS). En pédiatrie, les formes cliniques ont un…”
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Profil épidémiologique et clinique des enfants atteints de la maladie à Corona Virus (COVID-19) au Centre de Traitement des Epidémies et Prévention des Infections (CTEPI) du CHU de Donka à Conakry
Published in The Pan African medical journal (01-12-2020)“…La COVID-19 est due au virus SRAS-CoV-2 génétiquement semblable au virus du syndrome respiratoire aigu sévère (SRAS). En pédiatrie, les formes cliniques ont un…”
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