Data of Nebivolol on oxidative stress parameters in hypertensive patients

Oxidative stress is a key feature in hypertension, since reactive oxygen species are involved in all stages of cardiovascular diseases. Saliva is a body fluid that can be used to investigate alterations in the oxidative system with several specific advantages over blood. Nebivolol is a third-generat...

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Bibliographic Details
Published in:Data in brief Vol. 41; p. 107913
Main Authors: Barroso, Helena C., Graton, Murilo E., Potje, Simone R., Troiano, Jéssica A., Silva, Lilian X., Nakamune, Ana Cláudia M.S., Antoniali, Cristina
Format: Journal Article
Language:English
Published: Netherlands Elsevier Inc 01-04-2022
Elsevier
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Summary:Oxidative stress is a key feature in hypertension, since reactive oxygen species are involved in all stages of cardiovascular diseases. Saliva is a body fluid that can be used to investigate alterations in the oxidative system with several specific advantages over blood. Nebivolol is a third-generation selective β1-adrenergic receptor antagonist that promotes vasodilation and has been shown to reduce oxidative stress in pre-clinical and clinical studies. The use of Nebivolol in different periods of treatment demonstrated that it is an efficient anti-hypertensive drug. We evaluated the oxidative stress biomarkers and the enzymatic and non-enzymatic antioxidant systems in saliva of hypertensive patients before and after the use of anti-hypertensive therapeutic doses of Nebivolol, since saliva can be used as an auxiliary tool to analyze parameters of oxidative stress.
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ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2022.107913