Search Results - "Barros, Mário Henrique M."
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Macrophage polarisation: an immunohistochemical approach for identifying M1 and M2 macrophages
Published in PloS one (15-11-2013)“…Macrophage polarization is increasingly recognised as an important pathogenetic factor in inflammatory and neoplastic diseases. Proinflammatory M1 macrophages…”
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Tumor-associated macrophages in classical Hodgkin lymphoma: hormetic relationship to outcome
Published in Scientific reports (10-06-2020)“…Commonly attributed to the prevalence of M2 macrophages, tumor-associated macrophages (TAM) are linked to poor outcome in Hodgkin lymphoma (HL). MYC is…”
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Revisiting the Tissue Microenvironment of Infectious Mononucleosis: Identification of EBV Infection in T Cells and Deep Characterization of Immune Profiles
Published in Frontiers in immunology (20-02-2019)“…To aid understanding of primary EBV infection, we have performed an in depth analysis of EBV-infected cells and of local immune cells in tonsils from…”
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4
Tumor microenvironment composition in pediatric classical Hodgkin lymphoma is modulated by age and Epstein-Barr virus infection
Published in International journal of cancer (01-09-2012)“…Classical Hodgkin lymphoma (cHL) is characterized by a small number of neoplastic cells in a background of reactive cells. Children and adults differ in…”
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Interleukin 10 (IL10) proximal promoter polymorphisms beyond clinical response in classical Hodgkin lymphoma: Exploring the basis for the genetic control of the tumor microenvironment
Published in Oncoimmunology (04-05-2018)“…Interleukin-10 (IL10) is an immune regulatory cytokine. Single nucleotide polymorphisms (SNPs) in IL10 promoter have been associated with prognosis in adult…”
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Tumor-Associated Macrophages in Pediatric Classical Hodgkin Lymphoma: Association with Epstein-Barr Virus, Lymphocyte Subsets, and Prognostic Impact
Published in Clinical cancer research (15-07-2012)“…Tumor-infiltrating macrophages are associated with adverse outcome in adult classical Hodgkin lymphoma (cHL). We have previously shown age-related changes in…”
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Syncytial neoplastic cells in paediatric Hodgkin lymphoma
Published in European journal of haematology (01-01-2009)Get full text
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Pathway‐focused gene expression profiles and immunohistochemistry detection identify contrasting association of caspase 3 (CASP3) expression with prognosis in pediatric classical Hodgkin lymphoma
Published in Hematological oncology (01-10-2018)“…The search for clinically relevant molecular markers in classical Hodgkin lymphoma (cHL) is hampered by the histopathological complexity of the disease,…”
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Human Natural Killer Cells Prevent Infectious Mononucleosis Features by Targeting Lytic Epstein-Barr Virus Infection
Published in Cell reports (Cambridge) (01-12-2013)“…Primary infection with the human oncogenic Epstein-Barr virus (EBV) can result in infectious mononucleosis (IM), a self-limiting disease caused by massive…”
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Disease patterns in pediatric classical Hodgkin lymphoma: a report from a developing area in Brazil
Published in Hematological oncology (01-12-2011)“…Epidemiological patterns established about 20 years ago, divided classical Hodgkin lymphoma (cHL) in three entities with regard to Epstein–Barr virus (EBV)…”
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Analysis of biological and technical variability in gene expression assays from formalin-fixed paraffin-embedded classical Hodgkin lymphomas
Published in Experimental and molecular pathology (01-12-2014)“…Formalin-fixed paraffin-embedded (FFPE) tissues are invaluable sources of biological material for research and diagnostic purposes. In this study, we aimed to…”
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Prevalence of HPV infection in head and neck carcinomas shows geographical variability: a comparative study from Brazil and Germany
Published in Virchows Archiv : an international journal of pathology (01-06-2015)“…Rising prevalence rates of high-risk human papillomaviruses (hrHPV) infection in oropharyngeal carcinoma (up to 80 %) have been reported in North America and…”
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Detection of HPV infection in head and neck squamous cell carcinoma: a practical proposal
Published in Virchows Archiv : an international journal of pathology (01-04-2013)“…Detecting human papillomavirus (HPV) infection in head and neck squamous cell carcinoma (HNSCC) is clinically relevant, but there is no agreement about the…”
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Cell cycle characteristics and Epstein-Barr virus are differentially associated with aggressive and non-aggressive subsets of Hodgkin lymphoma in pediatric patients
Published in Leukemia & lymphoma (01-08-2010)“…We investigated the correlation of tumor characteristics with clinico-biological markers of aggressive disease, evaluated by Ann Arbor stage, risk group,…”
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15
Editorial: Epstein-Barr virus and its contribution to pediatric tumors
Published in Frontiers in oncology (08-09-2022)Get full text
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Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression
Published in Cell host & microbe (12-07-2017)“…The human tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) establish persistent infections in B cells. KSHV is linked to…”
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Contribution of the Epstein-Barr virus to the oncogenesis of mature T-cell lymphoproliferative neoplasms
Published in Frontiers in oncology (14-09-2023)“…EBV is a lymphotropic virus, member of the family that asymptomatically infects more than 90% of the human population, establishing a latent infection in…”
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Clinical and laboratorial prediction of bone marrow involvement in children and adolescents with Hodgkin Lymphoma
Published in Pediatric Blood & Cancer (01-04-2008)“…Background A risk group (RG) system to predict bone marrow involvement (BMI) based on clinical and laboratory parameters was previously shown to have…”
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Prognostic impact of CD15 expression and proliferative index in the outcome of children with classical Hodgkin lymphoma
Published in Pediatric Blood & Cancer (01-02-2008)Get full text
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Number of involved anatomic areas as a risk predictor in pediatric Hodgkin's lymphoma: a retrospective study
Published in Jornal de pediatria (01-05-2009)“…To determine if the number of involved anatomic areas can modify the standard risk groups in pediatric Hodgkin's lymphoma, identifying children who would…”
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