Search Results - "Barros, Luciana C"

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    A comparative analysis of noise properties of stochastic binary models for a self-repressing and for an externally regulating gene by Giovanini, Guilherme, Sabino, Alan U, Barros, Luciana R C, Ramos, Alexandre F

    “…This manuscript presents a comparison of noise properties exhibited by two stochastic binary models for: (i) a self-repressing gene; (ii) a repressed or…”
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    Journal Article
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    Modeling Patient-Specific CAR-T Cell Dynamics: Multiphasic Kinetics via Phenotypic Differentiation by Paixão, Emanuelle A, Barros, Luciana R C, Fassoni, Artur C, Almeida, Regina C

    Published in Cancers (14-11-2022)
    “…Chimeric Antigen Receptor (CAR)-T cell immunotherapy revolutionized cancer treatment and consists of the genetic modification of T lymphocytes with a CAR gene,…”
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    A Stochastic Binary Model for the Regulation of Gene Expression to Investigate Responses to Gene Therapy by Giovanini, Guilherme, Barros, Luciana R C, Gama, Leonardo R, Tortelli, Jr, Tharcisio C, Ramos, Alexandre F

    Published in Cancers (27-01-2022)
    “…In this manuscript, we use an exactly solvable stochastic binary model for the regulation of gene expression to analyze the dynamics of response to a treatment…”
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    CARTmath—A Mathematical Model of CAR-T Immunotherapy in Preclinical Studies of Hematological Cancers by Barros, Luciana R. C., Paixão, Emanuelle A., Valli, Andrea M. P., Naozuka, Gustavo T., Fassoni, Artur C., Almeida, Regina C.

    Published in Cancers (11-06-2021)
    “…Immunotherapy has gained great momentum with chimeric antigen receptor T cell (CAR-T) therapy, in which patient’s T lymphocytes are genetically manipulated to…”
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    Abnormal Long Non-Coding RNAs Expression Patterns Have the Potential Ability for Predicting Survival and Treatment Response in Breast Cancer by Pavanelli, Ana Carolina, Mangone, Flavia Rotea, Barros, Luciana R C, Machado-Rugolo, Juliana, Capelozzi, Vera L, Nagai, Maria A

    Published in Genes (29-06-2021)
    “…Abnormal long non-coding RNAs (lncRNAs) expression has been documented to have oncogene or tumor suppressor functions in the development and progression of…”
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    Mechanisms of resistance to CAR-T cell immunotherapy: Insights from a mathematical model by Santurio, Daniela Silva, Paixão, Emanuelle A., Barros, Luciana R.C., Almeida, Regina C., Fassoni, Artur C.

    Published in Applied mathematical modelling (01-01-2024)
    “…Chimeric Antigen Receptor (CAR)-T cell therapy long-term follow-up studies revealed non-durable remissions in a significant number of patients. Some of the…”
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    CART math -A Mathematical Model of CAR-T Immunotherapy in Preclinical Studies of Hematological Cancers by Barros, Luciana R C, Paixão, Emanuelle A, Valli, Andrea M P, Naozuka, Gustavo T, Fassoni, Artur C, Almeida, Regina C

    Published in Cancers (11-06-2021)
    “…Immunotherapy has gained great momentum with chimeric antigen receptor T cell (CAR-T) therapy, in which patient's T lymphocytes are genetically manipulated to…”
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    Journal Article
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    Abstract P4-12-14: Assessing patients perceptions on hormone therapy for breast cancer: Insights from a Brazilian patient group by Montemor, Marina S, Neumann, Lycia TV, Siqueira, Anna CA, Barros, Luciana HC, Sanches, Solange M

    Published in Cancer research (Chicago, Ill.) (15-02-2022)
    “…Introduction Breast cancer has a high incidence in the population, and it still is a major cause of mortality among women. About 2/3 of these tumors express…”
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    Journal Article